Physico-chemical aspects of calcium stone formation

1990 ◽  
Vol 18 (1) ◽  
pp. S25-S30 ◽  
Author(s):  
J. M. Baumann
1987 ◽  
Vol 33 (2) ◽  
pp. 243-247 ◽  
Author(s):  
D M Cowley ◽  
B C McWhinney ◽  
J M Brown ◽  
A H Chalmers

Abstract An investigation of variables important to calcium stone formation in urine indicated significantly increased daily excretion of calcium and oxalate and decreased excretion of ascorbate and citrate by recurrent calcium stone formers. In addition, urine volume, sodium, mucopolysaccharide, and protein were also significantly increased. We compared the uptake of citrate and ascorbate from the gut into the blood in normal controls and stone formers. These studies indicated significantly depressed absorption of both these hydroxycarboxylic acids in recurrent calcium stone formers. We also found that concurrent administration of citrate inhibited ascorbate absorption and increased urinary oxalate excretion after an ascorbate load in normal subjects and stone formers. These findings suggest a mechanism that explains hyperoxaluria in stone patients on the basis of a malabsorption of citrate, ascorbate, and possibly other hydroxycarboxylic acids.


1996 ◽  
Vol 24 (1) ◽  
pp. 39-43 ◽  
Author(s):  
P. Eriksson ◽  
T. Denneberg ◽  
H. -G. Tiselius

1980 ◽  
Vol 123 (1) ◽  
pp. 9-13 ◽  
Author(s):  
U. Backman ◽  
B.G. Danielson ◽  
G. Johansson ◽  
S. Ljunghall ◽  
B. Wikström

2001 ◽  
Vol 29 (6) ◽  
pp. 417-422 ◽  
Author(s):  
J. Baumann ◽  
B. Affolter ◽  
U. Caprez ◽  
U. Henze ◽  
D. Lauper ◽  
...  

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