The effect of diverting colostomy on anastomotic healing after resection of left colon obstruction

1990 ◽  
Vol 5 (3) ◽  
pp. 167-169 ◽  
Author(s):  
A. T�rnqvist ◽  
P. Blomquist ◽  
H. Jiborn ◽  
B. Zederfeldt
Keyword(s):  
Left Colon ◽  
Anastomotic Healing ◽  
Colon Obstruction ◽  
Diverting Colostomy

Effect of Ischemia/Reperfusion as a Systemic Phenomenon on Anastomotic Healing in the Left Colon

2000 ◽  
Vol 24 (8) ◽  
pp. 990-994 ◽  
Author(s):  
Mehmet Ayhan Kuzu ◽  
Adil Tanık ◽  
İIlhami Taner Kale ◽  
Ahmet Keşşaf Aşlar ◽  
Cüneyt Köksoy ◽  
...  
Keyword(s):  
Ischemia Reperfusion ◽  
Left Colon ◽  
Anastomotic Healing

Interposition of a Jejunal Segment as an Alternative One-Stage Operation for Acute Left Colon Obstruction

Surgery Today ◽  
2002 ◽  
Vol 32 (9) ◽  
pp. 804-808 ◽  
Author(s):  
Dan D. Hershko ◽  
Bishara Bishara ◽  
James H. Paxton ◽  
Bruce W. Robb ◽  
Curtis J. Wray ◽  
...  
Keyword(s):  
Left Colon ◽  
Jejunal Segment ◽  
Colon Obstruction ◽  
One Stage

scholarly journals Laparoscopic colostomy for acute left colon obstruction caused by diverticular disease in high risk patient: A case report

2015 ◽  
Vol 12 ◽  
pp. 78-80
Author(s):  
Elisa Palladino ◽  
Antonio Cappiello ◽  
Vincenzo Guarino ◽  
Nicola Perrotta ◽  
Domenico Loffredo
Keyword(s):  
Case Report ◽  
High Risk ◽  
Diverticular Disease ◽  
High Risk Patient ◽  
Left Colon ◽  
Risk Patient ◽  
Colon Obstruction

Surgical management of left colon obstruction: the University of Minnesota experience

1998 ◽  
Vol 187 (6) ◽  
pp. 573-576 ◽  
Author(s):  
Kemal I. Deen ◽  
Robert D. Madoff ◽  
Stanley M. Goldberg ◽  
David A. Rothenberger
Keyword(s):  
Surgical Management ◽  
Left Colon ◽  
University Of Minnesota ◽  
Colon Obstruction ◽  
The University

Anastomotic healing after resection of left-colon stenosis

1990 ◽  
Vol 33 (3) ◽  
pp. 217-221 ◽  
Author(s):  
Anders Törnqvist ◽  
Peter Blomquist ◽  
Hasse Jiborn ◽  
Bengt Zederfeldt
Keyword(s):  
Left Colon ◽  
Anastomotic Healing ◽  
Colon Stenosis

Usefulness of an Open Cecostomy in the Treatment of a Distal Colon Obstruction

2010 ◽  
Vol 26 (2) ◽  
pp. 111
Author(s):  
Jung-Cheol Kuk ◽  
Eun-Joo Jung ◽  
Chun-Geun Ryu ◽  
Sun-Mi Moon ◽  
Dae-Yong Hwang
Keyword(s):  
Distal Colon ◽  
Colon Obstruction

Use of indocianine green fluorescence in acute mesenteric ischemia

2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Jaime Bonnín-Pascual
Keyword(s):  
Indocyanine Green ◽  
Terminal Ileum ◽  
Mesenteric Ischemia ◽  
Intestinal Anastomosis ◽  
Acute Mesenteric Ischemia ◽  
Left Colon ◽  
Infrared Light ◽  
High Morbidity ◽  
Green Fluorescence ◽  
Clinical Cases

Introduction: Acute mesenteric ischemia has a high morbidity and mortality and constitutes an intraoperative challenge in the management of ischemic areas. In this context, we analyze the use of indocyanine green fluorescence to assess intestinal vascularization through 3 clinical cases. Case presentation: we present 3 clinical cases operated for acute mesenteric ischemia. Evaluation of intestinal viability is performed under infrared light after intravenous infusion of 25 mg of indocyanine green. Case 1 is a 42-year-old male with multiple antecedents of severe vascular disease, presenting with a massive acute mesenteric ischemia involving multiple intestinal segments. Fluorescence allows two adjusted bowel resections with double intestinal anastomosis. Case 2 is a 74-year-old woman with a history of non-anticoagulated atrial fibrillation who is decided to perform an urgent surgery when an esophageal, gastric and portal system pneumatosis is observed, as indirect signs of ischemia, in urgent CT. During the surgical act there is an ischemia of the terminal ileum and right colon without clear signs of involvement at the esophageal-gastric level. The assessment after administration of ICG discriminates the clear ischemic involvement from terminal ileum to ascending colon and patched in the transverse and left colon, without esophageal or gastric involvement. Case 3 is a 49-year-old woman with aortoiliac and visceral Takayasu disease and revascularization surgery of the celiac trunk. Given the increase in abdominal pain, a new CT scan demonstrates colonic pneumatosis. Urgent laparotomy shows necrosis at the level of the left colon and hypoperfusion of the cecum. The administration of ICG finds a lack of uptake of the entire colon. A subtotal colectomy with ileostomy and mucous fistula is performed. Introduction: Acute mesenteric ischemia has a high morbidity and mortality and constitutes an intraoperative challenge in the management of ischemic areas. In this context, we analyze the use of indocyanine green fluorescence to assess intestinal vascularization through 3 clinical cases. Case presentation: we present 3 clinical cases operated for acute mesenteric ischemia. Evaluation of intestinal viability is performed under infrared light after intravenous infusion of 25 mg of indocyanine green. Case 1 is a 42-year-old male with multiple antecedents of severe vascular disease, presenting with a massive acute mesenteric ischemia involving multiple intestinal segments. Fluorescence allows two adjusted bowel resections with double intestinal anastomosis. Case 2 is a 74-year-old woman with a history of non-anticoagulated atrial fibrillation who is decided to perform an urgent surgery when an esophageal, gastric and portal system pneumatosis is observed, as indirect signs of ischemia, in urgent CT. During the surgical act there is an ischemia of the terminal ileum and right colon without clear signs of involvement at the esophageal-gastric level. The assessment after administration of ICG discriminates the clear ischemic involvement from terminal ileum to ascending colon and patched in the transverse and left colon, without esophageal or gastric involvement. Case 3 is a 49-year-old woman with aortoiliac and visceral Takayasu disease and revascularization surgery of the celiac trunk. Given the increase in abdominal pain, a new CT scan demonstrates colonic pneumatosis. Urgent laparotomy shows necrosis at the level of the left colon and hypoperfusion of the cecum. The administration of ICG finds a lack of uptake of the entire colon. A subtotal colectomy with ileostomy and mucous fistula is performed. Conclusions: The fluorescence with ICG provides a better visualization of the intestinal vascularization in the AMI, and allows to determine the limits of the affected tissue to perform adjusted resections.

scholarly journals Congestive ischemic colitis occurring after resection of left colon cancer: 4 case series

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Takatsugu Fujii ◽  
Shigeo Toda ◽  
Yuki Nishihara ◽  
Yusuke Maeda ◽  
Kosuke Hiramatsu ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Ischemic Colitis ◽  
Case Series ◽  
Left Colon ◽  
Left Colon Cancer

scholarly journals Ileocolonic Healing After Extended Small Bowel Resection in Mice: NOD2 Deficiency Impairs Anastomotic Healing and Postoperative Outcome

2021 ◽  
Author(s):  
Maria Witte ◽  
Johannes Reiner ◽  
Karen Bannert ◽  
Robert Jaster ◽  
Christian Maschmeier ◽  
...  
Keyword(s):  
Gene Expression ◽  
Crohn Disease ◽  
Transforming Growth Factor ◽  
Bowel Resection ◽  
Anastomotic Healing ◽  
Matrix Metalloproteinase 2 ◽  
Ileocecal Resection ◽  
Bursting Pressure ◽  
Septic Complications ◽  
Gelatinase Activity

Abstract Background Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) mutations are a genetic risk factor for Crohn disease. Ileocecal resection is the most often performed surgery in Crohn disease. We investigated the effect of Nod2 knockout (KO) status on anastomotic healing after extended ileocecal resection (ICR) in mice. Methods Male C57BL6/J wild-type and Nod2 KO mice underwent an 11 cm resection of the terminal ileum including the cecum. An end-to-end jejuno-colostomy was performed. Animals were killed after 5 days investigating bursting pressure, hydroxyproline content, and expression of matrix metabolism genes, key cytokines, and histology of the anastomosis. Results Mortality was higher in the Nod2 KO group but not because of local or septic complications. Bursting pressure was significantly reduced in the Nod2 KO mice (32.5 vs 78.0 mmHg, P < 0.0024), whereas hydroxyprolin content was equal. The amount of granulation tissue at the anastomosis was similar but more unstructured in the Nod2 KO mice. Gene expression measured by real-time polymerase chain reaction showed significantly increased expression for Collagen 1alpha and for collagen degradation as measured by matrix metalloproteinase-2, -9, and -13 in the Nod2 KO mice. Gelatinase activity from anastomotic tissue was enhanced by Nod2 status. Gene expression of arginase I, tumor necrosis factor-α, and transforming growth factor-ß but not inducible nitric oxide synthase were also increased at the anastomosis in the Nod2 KO mice compared with the control mice. Conclusions We found that Nod2 deficiency results in significantly reduced bursting pressure after ileocecal resection. This effect is mediated via an increased matrix turnover. Patients with genetic NOD2 variations may be prone to anastomotic failure after bowel resection.

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