Serum intact parathyroid hormone in a random population sample of men and women: Relationship to anthropometry, life-style factors, blood pressure, and vitamin D

1995 ◽  
Vol 56 (2) ◽  
pp. 104-108 ◽  
Author(s):  
K. Landin-Wilhelmsen ◽  
L. Wilhelmsen ◽  
G. Lappas ◽  
T. Ros�n ◽  
G. Lindstedt ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Life Style ◽  
Population Sample ◽  
Intact Parathyroid Hormone ◽  
Men And Women ◽  
Random Population Sample

scholarly journals Parathyroid hormone has an important role in blood pressure regulation in vitamin D–insufficient individuals

Nutrition ◽  
2013 ◽  
Vol 29 (9) ◽  
pp. 1147-1151
Author(s):  
Vivian Cristina Garcia ◽  
Natielen Jacques Schuch ◽  
Antonela Siqueira Catania ◽  
Sandra Roberta Gouvea Ferreira ◽  
Lígia Araújo Martini
Keyword(s):  
Blood Pressure ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Blood Pressure Regulation ◽  
Pressure Regulation

scholarly journals Adiposity in Relation to Vitamin D Status and Parathyroid Hormone Levels: A Population-Based Study in Older Men and Women

2005 ◽  
Vol 90 (7) ◽  
pp. 4119-4123 ◽  
Author(s):  
Marieke B. Snijder ◽  
Rob M. van Dam ◽  
Marjolein Visser ◽  
Dorly J. H. Deeg ◽  
Jacqueline M. Dekker ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Older Men ◽  
Population Based ◽  
Vitamin D Status ◽  
Population Based Study ◽  
Men And Women ◽  
Hormone Levels ◽  
Older Men And Women

scholarly journals Associations between Serum-Intact Parathyroid Hormone, Serum 25-Hydroxyvitamin D. Oral Vitamin D Analogs and Metabolic Syndrome in Peritoneal Dialysis Patients: A Multi-Center Cross-Sectional Study

2014 ◽  
Vol 34 (4) ◽  
pp. 447-455 ◽  
Author(s):  
Jie Dong ◽  
Qin Wang ◽  
Meng-Hua Chen ◽  
Hui-Ping Zhao ◽  
Tong-Ying Zhu ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Peritoneal Dialysis ◽  
Parathyroid Hormone ◽  
Lower Risk ◽  
Intact Parathyroid Hormone ◽  
Oral Vitamin ◽  
Vitamin D Analogs ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

Introduction Although previous studies have suggested associations between serum intact parathyroid hormone (iPTH), 25-hydroxyvitamin D (25(OH)D) and metabolic syndrome (MS) in the general population, these associations are still uncharacterized in peritoneal dialysis (PD) patients. Methods In total, 837 prevalent PD patients from 5 centers in China were enrolled between April 1, 2011 and November 1, 2011. The demographic data, biochemical parameters and medical records were collected, except for serum 25(OH)D which was measured in 347 of 837 patients. The definition of MS was modified from National Cholesterol Education Program Third Adult Treatment Panel (NCEP-ATPIII). Results 55.4% of 837 patients were found to have MS. The median concentration of iPTH, 25(OH)D and doses of oral vitamin D analogs for participants with MS was significantly lower than those without MS. The iPTH, 25(OH)D values and doses of vitamin D analogs were all associated with one or more components of MS. After multivariate adjustment, Low serum iPTH values and oral vitamin D analogs, rather than serum 25(OH)D, were significantly associated with the presence of MS, abnormal fasting blood glucose (FBG) and high-density lipoprotein cholesterol (HDL-C). Compared to iPTH < 130pg/mL, iPTH 130–585 pg/mL and > 585pg/mL were associated with a lower risk of MS with adjusted odds ratio (OR) of 0.59 and 0.33, respectively. Taking vitamin D analogs was also associated with a lower risk of MS with adjusted OR of 0.55. Conclusions Serum iPTH and the use of active vitamin D supplements rather than serum 25(OH)D were independently associated with the presence of MS in patients on PD.

scholarly journals EFFECTS OF VITAMIN D SUPPLEMENTATION ON WELL-BEING, POSTURAL CONTROL, MUSCLE STRENGTH, BONE AND CALCITROPIC HORMONES – A RANDOMIZED DOUBLEBLIND PLACEBO CONTROLLED TRIAL

2019 ◽  
pp. 1-8
Author(s):  
S.A. Eriksen ◽  
J. Starup-Linde ◽  
R.P. Hirata ◽  
K.K. Petersen ◽  
T. Graven-Nielsen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Major Depression ◽  
Postural Control ◽  
Pain Sensitivity ◽  
Handgrip Strength ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Intact Parathyroid Hormone ◽  
Major Depression Inventory

Background: Antidepressants may increase the risk of fractures through negative effects on the musculoskeletal system that could be hindered by vitamin D supplements. Objectives: To study the pleiotropic effects of daily vitamin D supplementation in depressed patients treated with citalopram (patients) and healthy controls. Design: Randomised double blind placebo controlled trial. Setting: A study of Danish women in the age 50 to 90 years. Participants: A total of 21 patients and 50 controls. Intervention: Participants received daily vitamin D supplementation (50 micrograms) or placebo in one year. Measurements: Bone Densitometry by dual-energy x-ray absorptiometry. Serum 25-hydroxyvitamin D, intact-Parathyroid Hormone, type 1 procollagen N terminal peptide, tartrate resistant acid phosphatase type 5b. Pain sensitivity measures based on pain detection thresholds by cuff algometry, temporal summation of pain, conditioned pain modulation, and cutaneous pain sensitivity by pinprick test. Degree of depression by the Major Depression Inventory. Physical performance was assessed by Timed up and go, isomeric handgrip exercise, and postural control by force plate. Results: Serum 25(OH)D levels increased in the vitamin D treated patients compared with controls at the 12 months visit (P<0.05). Conversely, intact- Parathyroid Hormone decreased among the patients and controls receiving vitamin D compared with placebo (P<0.05). Vitamin D improved Major Depression Inventory scores in patients and controls compared with placebo (P<0.05). In patients receiving vitamin D, handgrip strength improved (P<0.05). Conclusions: Vitamin D may improve depressive symptoms, and improve handgrip strength among patients compared to controls.

Vitamin D supply among healthy blood donors in County Vas, Hungary

2012 ◽  
Vol 153 (41) ◽  
pp. 1629-1637 ◽  
Author(s):  
Éva Virágh ◽  
Dóra Horváth ◽  
Zoltán Lőcsei ◽  
László Kovács ◽  
Rita Jáger ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Oral Contraceptives ◽  
Blood Donors ◽  
Elderly Subjects ◽  
Intact Parathyroid Hormone ◽  
Hydroxyvitamin D ◽  
Vitamin D Levels ◽  
25 Hydroxyvitamin D ◽  
The Impact

Introduction: There is growing evidence showing the importance of adequate vitamin D supply for preserving health. Aim: The aim of the study was to evaluate the vitamin D supply among healthy blood donors and healthy elderly subjects in County Vas, Hungary. Methods: Serum 25-hydroxyvitamin D, intact parathyroid hormone, calcium and albumin (Cobas, Modular, Roche), as well as serum alfa-2-globulin concentrations (Gelelfo, Interlab) were determined in 178 serum samples (68 men, 110 women, 41 were taking oral contraceptives). The results were analysed according to sex and age (younger and older than 43 years), and the impact of oral contraceptive use was also taken into consideration. Results: Deficiency and insufficiency in vitamin D levels were detected in 9.6% and 32% of the studied subjects, respectively, whereas sufficient vitamin D levels were present in 58.4% of the subjects. 63% of the older and 41.2% of the younger group had suboptimal vitamin-D supply (p < 0.01). In women taking oral contraceptives serum 25-hydroxyvitamin D and alfa-2-globulin levels were significantly higher, whereas serum albumin and calcium levels were lower than in the control group. There was no difference in serum intact parathyroid hormone concentration between oral anticoncipient users and non-users. Conclusions: The occurrence of suboptimal vitamin D supply is significant, although less frequent than that in literature reports. In women taking oral contraceptives, serum 25-hydroxyvitamin D levels were higher, but serum intact parathyroid hormone concentrations were not decreased suggesting that the increased 25-hydroxyvitamin D levels may be the consequence of oestrogen-induced alterations of serum protein fractions. Orv. Hetil., 2012, 153, 1629–1637.

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