Genetic analysis of human lymphocyte proteins by two-dimensional gel electrophoresis

1985 ◽  
Vol 70 (4) ◽  
pp. 328-332 ◽  
Author(s):  
I. Kondo ◽  
T. Yamamoto ◽  
K. Yamakawa ◽  
M. Shibasaki ◽  
H. Hamaguchi
1986 ◽  
Vol 72 (4) ◽  
pp. 303-306 ◽  
Author(s):  
I. Kondo ◽  
S. Harada ◽  
M. Shibasaki ◽  
K. Yamakawa ◽  
T. Yamamoto ◽  
...  

1981 ◽  
Vol 59 (3) ◽  
Author(s):  
Hideo Hamaguchi ◽  
Akihide Ohta ◽  
Ryozaburo Mukai ◽  
Toshio Yabe ◽  
Michiko Yamada

1982 ◽  
Vol 60 (2) ◽  
pp. 176-180 ◽  
Author(s):  
Hideo Hamaguchi ◽  
Michiko Yamada ◽  
Atsuo Noguchi ◽  
Keiji Fujii ◽  
Masanao Shibasaki ◽  
...  

1984 ◽  
Vol 66 (2-3) ◽  
pp. 248-251 ◽  
Author(s):  
I. Kondo ◽  
T. Yamamoto ◽  
K. Yamakawa ◽  
S. Harada ◽  
H. Oishi ◽  
...  

1984 ◽  
Vol 66 (2-3) ◽  
pp. 244-247 ◽  
Author(s):  
I. Kondo ◽  
K. Yamakawa ◽  
M. Shibasaki ◽  
T. Yamamoto ◽  
H. Hamaguchi

1985 ◽  
Vol 54 (03) ◽  
pp. 626-629 ◽  
Author(s):  
M Meyer ◽  
F H Herrmann

SummaryThe platelet proteins of 9 thrombasthenic patients from 7 families were analysed by high resolution two-dimensional gel electrophoresis (HR-2DE) and crossed immunoelectrophoresis (CIE). In 7 patients both glycoproteins (GPs) IIb and Ilia were absent or reduced to roughly the same extent. In two related patients only a trace of GP Ilb-IIIa complex was detected in CIE, but HR-2DE revealed a glycopeptide in the position of GP Ilia in an amount comparable to type II thrombasthenia. This GP Ilia-like component was neither recognized normally by anti-GP Ilb-IIIa antibodies nor labeled by surface iodination. In unreduced-reduced two-dimensional gel electrophoresis two components were observed in the region of GP Ilia. The assumption of a structural variant of GP Ilia in the two related patients is discussed.


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