A new and simple technique for chromosomal preparations from peripheral blood lymphocytes, amniotic cell cultures, skin fibroblasts, bone marrow and single cell clones when the yields from harvests are low

1980 ◽  
Vol 55 (3) ◽  
pp. 363-366 ◽  
Author(s):  
Barathur R. Rajendra ◽  
Leonard J. Sciorra ◽  
Ming-liang Lee
Blood ◽  
1984 ◽  
Vol 64 (2) ◽  
pp. 352-356
Author(s):  
GJ Ruiz-Arguelles ◽  
JA Katzmann ◽  
PR Greipp ◽  
NJ Gonchoroff ◽  
JP Garton ◽  
...  

The bone marrow and peripheral blood of 14 patients with multiple myeloma were studied with murine monoclonal antibodies that identify antigens on plasma cells (R1–3 and OKT10). Peripheral blood lymphocytes expressing plasma cell antigens were found in six cases. Five of these cases expressed the same antigens that were present on the plasma cells in the bone marrow. Patients that showed such peripheral blood involvement were found to have a larger tumor burden and higher bone marrow plasma cell proliferative activity. In some patients, antigens normally found at earlier stages of B cell differentiation (B1, B2, and J5) were expressed by peripheral blood lymphocytes and/or bone marrow plasma cells.


2014 ◽  
Vol 29 (7) ◽  
pp. 423-428 ◽  
Author(s):  
Conceição Aparecida Dornelas ◽  
Bruno Coelho Cavalcanti ◽  
Hemerson Iury Ferreira Magalhães ◽  
Francisco Vagnaldo Fechine Jamacaru ◽  
Francisco Nelson Nóbrega Furtado ◽  
...  

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