Two cases of the Langer-Giedion syndrome with the same interstitial deletion of the long arm of chromosome 8: 46,XY or XX,del(8)(q23.3q24.13)

1983 ◽  
Vol 64 (1) ◽  
pp. 90-93 ◽  
Author(s):  
Y. Fukushima ◽  
Y. Kuroki ◽  
T. Izawa
Keyword(s):  
Interstitial Deletion ◽  
Chromosome 8

Terminal or interstitial deletion in chromosome 8 long arm in Langer-Giedion syndrome (TRP II syndrome)?

1983 ◽  
Vol 64 (2) ◽  
pp. 163-166 ◽  
Author(s):  
Erica M. B�hler ◽  
U. K. B�hler ◽  
R. Christen
Keyword(s):  
Interstitial Deletion ◽  
Chromosome 8

Congenital spherocytosis, B19 parvovirus infection and inherited interstitial deletion of the short arm of chromosome 8

1991 ◽  
Vol 78 (2) ◽  
pp. 251-257 ◽  
Author(s):  
H. Cohen ◽  
H. Walker ◽  
J. D. A. Delhanty ◽  
S. B. Lucas ◽  
E. R. Huehns
Keyword(s):  
Interstitial Deletion ◽  
Chromosome 8 ◽  
B19 Parvovirus

Vision Impairment with an Interstitial Deletion of the Short Arm of Chromosome 8

2007 ◽  
Vol 28 (2) ◽  
pp. 101-104 ◽  
Author(s):  
Rosalind M. K. Stewart ◽  
David C. Assheton ◽  
Richard P. Hagan ◽  
Arvind Chandna
Keyword(s):  
Interstitial Deletion ◽  
Chromosome 8 ◽  
Vision Impairment

Interstitial Deletion of the Long Arm of Chromosome 8 without Langer-Giedion Syndrome

1986 ◽  
Vol 40 (2) ◽  
pp. 221-226 ◽  
Author(s):  
Satoru Kazukawa ◽  
Masaomi Endo ◽  
Tsutomu Fujii ◽  
Ariyuki Hori ◽  
Kiyomi Yamada ◽  
...  
Keyword(s):  
Interstitial Deletion ◽  
Chromosome 8

588: Detection of Chromosome 8 Alterations in Paired Needle Biopsy and Prostatectomy Specimens Using Fluorescence In-Situ Hybridization

2004 ◽  
Vol 171 (4S) ◽  
pp. 156-156
Author(s):  
Chandler D. Dora ◽  
Yasushi Kondo ◽  
Fusheng X. Lan ◽  
Jeffrey M. Slezak ◽  
Erik J. Bergstralh ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Needle Biopsy ◽  
Chromosome 8

Interstitial deletion (2)(q11.2-q21) in a newborn with multiple malformations

2006 ◽  
Vol 37 (06) ◽  
Author(s):  
G Strobl-Wildemann ◽  
F Staudt ◽  
C Schmidtlein ◽  
U Heinrich
Keyword(s):  
Interstitial Deletion

scholarly journals Simultaneous genotypic and immunophenotypic analysis of interphase cells using dual-color fluorescence: a demonstration of lineage involvement in polycythemia vera

Blood ◽  
1992 ◽  
Vol 80 (4) ◽  
pp. 1033-1038 ◽  
Author(s):  
CM Price ◽  
EJ Kanfer ◽  
SM Colman ◽  
N Westwood ◽  
AJ Barrett ◽  
...  
Keyword(s):  
Polycythemia Vera ◽  
Fluorescent In Situ Hybridization ◽  
Chromosomal Abnormalities ◽  
Myeloproliferative Disorders ◽  
Chromosome 8 ◽  
Dual Fluorescence ◽  
Interphase Cell ◽  
Molecular Alterations ◽  
Interphase Cells

Abstract Fluorescent in situ hybridization has become a useful technique by which chromosomal abnormalities may be shown in interphase cells. We present a dual-fluorescence method whereby a chromosomal and immunophenotypic marker can be visualized simultaneously in the same interphase cell. Two patients with the myeloproliferative disorder polycythemia vera and trisomy for chromosome 8 have been studied using this technique and selective involvement of the myeloid and erythrocyte lineages has been shown by the detection of the trisomy in immunophenotyped cells. Simultaneous analysis of genotype and immunophenotype in individual cells from patients with myeloproliferative disorders or leukemia may help identify the developmental and lineage status of cells in which molecular alterations have resulted in clonal advantage.

scholarly journals Introgression of the sesquiterpene biosynthesis from Solanum habrochaites to cultivated tomato offers insights into trichome morphology and arthropod resistance

Planta ◽  
2021 ◽  
Vol 254 (1) ◽  
Author(s):  
Rodrigo Therezan ◽  
Ruy Kortbeek ◽  
Eloisa Vendemiatti ◽  
Saioa Legarrea ◽  
Severino M. de Alencar ◽  
...  
Keyword(s):  
Glandular Trichomes ◽  
Pest Resistance ◽  
Chromosome 8 ◽  
Cavity Size ◽  
Solanum Habrochaites ◽  
Genetic Components ◽  
Internal Storage ◽  
In The Wild ◽  
Low Levels ◽  
Trichome Morphology

Abstract Main conclusion Cultivated tomatoes harboring the plastid-derived sesquiterpenes from S. habrochaites have altered type-VI trichome morphology and unveil additional genetic components necessary for piercing-sucking pest resistance. Abstract Arthropod resistance in the tomato wild relative Solanum habrochaites LA1777 is linked to specific sesquiterpene biosynthesis. The Sesquiterpene synthase 2 (SsT2) gene cluster on LA1777 chromosome 8 controls plastid-derived sesquiterpene synthesis. The main genes at SsT2 are Z-prenyltransferase (zFPS) and Santalene and Bergamotene Synthase (SBS), which produce α-santalene, β-bergamotene, and α-bergamotene in LA1777 round-shaped type-VI glandular trichomes. Cultivated tomatoes have mushroom-shaped type-VI trichomes with much smaller glands that contain low levels of monoterpenes and cytosolic-derived sesquiterpenes, not presenting the same pest resistance as in LA1777. We successfully transferred zFPS and SBS from LA1777 to cultivated tomato (cv. Micro-Tom, MT) by a backcrossing approach. The trichomes of the MT-Sst2 introgressed line produced high levels of the plastid-derived sesquiterpenes. The type-VI trichome internal storage-cavity size increased in MT-Sst2, probably as an effect of the increased amount of sesquiterpenes, although it was not enough to mimic the round-shaped LA1777 trichomes. The presence of high amounts of plastid-derived sesquiterpenes was also not sufficient to confer resistance to various tomato piercing-sucking pests, indicating that the effect of the sesquiterpenes found in the wild S. habrochaites can be insect specific. Our results provide for a better understanding of the morphology of S. habrochaites type-VI trichomes and paves the way to obtain insect-resistant tomatoes.

scholarly journals Estimation of Cry3Bb1 resistance allele frequency in field populations of western corn rootworm using a genetic marker

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alan Willse ◽  
Lex Flagel ◽  
Graham Head
Keyword(s):  
Allele Frequency ◽  
Western Corn Rootworm ◽  
Allele Frequencies ◽  
Chromosome 8 ◽  
Corn Belt ◽  
Corn Rootworm ◽  
Resistance Allele ◽  
Response To Selection ◽  
The Us ◽  
Causal Allele

Abstract Following the discovery of western corn rootworm (WCR; Diabrotica virgifera virgifera) populations resistant to the Bacillus thuringiensis (Bt) protein Cry3Bb1, resistance was genetically mapped to a single locus on WCR chromosome 8 and linked SNP markers were shown to correlate with the frequency of resistance among field-collected populations from the US Corn Belt. The purpose of this paper is to further investigate the relationship between one of these resistance-linked markers and the causal resistance locus. Using data from laboratory bioassays and field experiments, we show that one allele of the resistance-linked marker increased in frequency in response to selection, but was not perfectly linked to the causal resistance allele. By coupling the response to selection data with a genetic model of the linkage between the marker and the causal allele, we developed a model that allowed marker allele frequencies to be mapped to causal allele frequencies. We then used this model to estimate the resistance allele frequency distribution in the US Corn Belt based on collections from 40 populations. These estimates suggest that chromosome 8 Cry3Bb1 resistance allele frequency was generally low (<10%) for 65% of the landscape, though an estimated 13% of landscape has relatively high (>25%) resistance allele frequency.

Sign in / Sign up

Export Citation Format

Share Document