Population genetics of adenosine deaminase (EC: 3.5.4.4): Gene frequencies in Southwestern Germany

1969 ◽  
Vol 7 (2) ◽  
pp. 179-179 ◽  
Author(s):  
G. Tariwerdian ◽  
H. Ritter
Genetics ◽  
1993 ◽  
Vol 133 (3) ◽  
pp. 711-727
Author(s):  
B K Epperson

Abstract The geographic distribution of genetic variation is an important theoretical and experimental component of population genetics. Previous characterizations of genetic structure of populations have used measures of spatial variance and spatial correlations. Yet a full understanding of the causes and consequences of spatial structure requires complete characterization of the underlying space-time system. This paper examines important interactions between processes and spatial structure in systems of subpopulations with migration and drift, by analyzing correlations of gene frequencies over space and time. We develop methods for studying important features of the complete set of space-time correlations of gene frequencies for the first time in population genetics. These methods also provide a new alternative for studying the purely spatial correlations and the variance, for models with general spatial dimensionalities and migration patterns. These results are obtained by employing theorems, previously unused in population genetics, for space-time autoregressive (STAR) stochastic spatial time series. We include results on systems with subpopulation interactions that have time delay lags (temporal orders) greater than one. We use the space-time correlation structure to develop novel estimators for migration rates that are based on space-time data (samples collected over space and time) rather than on purely spatial data, for real systems. We examine the space-time and spatial correlations for some specific stepping stone migration models. One focus is on the effects of anisotropic migration rates. Partial space-time correlation coefficients can be used for identifying migration patterns. Using STAR models, the spatial, space-time, and partial space-time correlations together provide a framework with an unprecedented level of detail for characterizing, predicting and contrasting space-time theoretical distributions of gene frequencies, and for identifying features such as the pattern of migration and estimating migration rates in experimental studies of genetic variation over space and time.


1980 ◽  
Vol 33 (3) ◽  
pp. 385 ◽  
Author(s):  
BJ Richardson

The differences in distribution of gene frequencies at three polymorphic loci (adenosine deaminase, carboxylesterase-1 and phosphogluconate dehydrogenase) were determined for rabbit populations living in two markedly different environments. One, a highland population from Snowy Plains N.S.W., has low productivity and high survival rates, and the second, a dry plains population from Urana, N.S.W., has high productivity and low survival rates. The amount of sub population differentiation at each locus was distinctive, and was different in the two environments with significant differentiation occurring for phosphogluconate dehydrogenase at both areas, for carboxylesterase-1 at Snowy Plains and for adenosine deaminase at Urana. The general significance of these results was demonstrated by determining the distribution of the variation in a third population. This population was subject to the same historical climatic events as the Urana population and showed a similar pattern of variation. Various explanations of the data are considered and a combination of chance and selection, rather than either alone, seems to offer the most satisfactory explanation. The demographic differences between the populations seemed to play no part in explaining the patterns observed.


2009 ◽  
pp. 75-111
Author(s):  
T. L. White ◽  
W. T. Adams ◽  
D. B. Neale

1972 ◽  
Vol 21 (1-2) ◽  
pp. 135-138 ◽  
Author(s):  
H. Ageheim ◽  
M. Bergström

SummaryAdenosine deaminase (ADA) isoenzymes in a Swedish population of 342 unrelated individuals have been determined according to the method of Spencer et al. (1968). The gene frequencies found were 0.9357 and 0.0643 for ADA 1 and ADA 2 respectively. These frequencies are in good accordance with previous investigations.


1970 ◽  
Vol 10 (3) ◽  
pp. 235-243 ◽  
Author(s):  
H. Werner Goedde ◽  
Heide-G. Benkmann ◽  
Ingeborg Christ ◽  
Surjit Singh ◽  
Ludwig Hirth

1973 ◽  
Vol 17 (2) ◽  
Author(s):  
P. Herzog ◽  
J. Bohatov�

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