Epstein-Barr virus-specific cytotoxic T cell responses in rheumatoid arthritis patients

1982 ◽  
Vol 2 (4) ◽  
pp. 155-159 ◽  
Author(s):  
J. S. H. Gaston ◽  
A. B. Rickinson ◽  
M. A. Epstein
Keyword(s):  
Rheumatoid Arthritis ◽  
T Cell ◽  
Epstein Barr Virus ◽  
T Cell Responses ◽  
Cytotoxic T Cell ◽  
Barr Virus ◽  
Cell Responses ◽  
Epstein Barr ◽  
Cytotoxic T Cell Responses

scholarly journals Lytic and Latent Antigens of the Human Gammaherpesviruses Kaposi's Sarcoma-Associated Herpesvirus and Epstein-Barr Virus Induce T-Cell Responses with Similar Functional Properties and Memory Phenotypes

2007 ◽  
Vol 81 (9) ◽  
pp. 4904-4908 ◽  
Author(s):  
Florian Bihl ◽  
Murli Narayan ◽  
John V. Chisholm ◽  
Leah M. Henry ◽  
Todd J. Suscovich ◽  
...  
Keyword(s):  
T Cell ◽  
Cellular Immunity ◽  
Kaposi's Sarcoma ◽  
Epstein Barr Virus ◽  
T Cell Responses ◽  
Kaposi’S Sarcoma ◽  
Barr Virus ◽  
Cell Responses ◽  
Epstein Barr ◽  
Kaposi’S Sarcoma Associated Herpesvirus

ABSTRACT The cellular immunity against Kaposi's sarcoma-associated herpesvirus (KSHV) is poorly characterized and has not been compared to T-cell responses against other human herpesviruses. Here, novel and dominant targets of KSHV-specific cellular immunity are identified and compared to T cells specific for lytic and latent antigens in a second human gammaherpesvirus, Epstein-Barr virus. The data identify a novel HLA-B57- and HLA-B58-restricted epitope in the Orf57 protein and show consistently close parallels in immune phenotypes and functional response patterns between cells targeting lytic or latent KSHV- and EBV-encoded antigens, suggesting common mechanisms in the induction of these responses.

Spontaneous T cell responses to Epstein‐Barr virus‐encoded BARF1 protein and derived peptides in patients with nasopharyngeal carcinoma: Bases for improved immunotherapy

2008 ◽  
Vol 123 (5) ◽  
pp. 1100-1107 ◽  
Author(s):  
Debora Martorelli ◽  
Karim Houali ◽  
Laura Caggiari ◽  
Emanuela Vaccher ◽  
Luigi Barzan ◽  
...  
Keyword(s):  
T Cell ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
T Cell Responses ◽  
Barr Virus ◽  
Cell Responses ◽  
Epstein Barr
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