Phenotypic properties of neoplastic cell lines developed from fetal rat brain cells in culture after exposure to ethylnitrosourea in vivo

1977 ◽  
Vol 89 (3) ◽  
pp. 273-295 ◽  
Author(s):  
O. D. Laerum ◽  
M. F. Rajewsky ◽  
M. Schachner ◽  
D. Stavrou ◽  
K. G. Haglid ◽  
...  
Keyword(s):  
Rat Brain ◽  
Cell Lines ◽  
Neoplastic Cell ◽  
Brain Cells ◽  
Phenotypic Properties ◽  
Cells In Culture ◽  
Fetal Rat ◽  
Fetal Rat Brain

INTERACTIONS BETWEEN FETAL RAT BRAIN CELLS AND MATURE BRAIN TISSUE IN VIVO AND IN VITRO

1993 ◽  
Vol 52 (3) ◽  
pp. 295 ◽  
Author(s):  
Kirsten Marienhagen ◽  
Paal-Henning Pedersen ◽  
Sverre Mork ◽  
Rolf Bierkvig
Keyword(s):  
Rat Brain ◽  
Brain Tissue ◽  
Brain Cells ◽  
Mature Brain ◽  
Fetal Rat ◽  
Fetal Rat Brain

Thyroid Hormone Action on Biosynthesis of Somatostatin by Fetal Rat Brain Cells in Culture*

Endocrinology ◽  
1988 ◽  
Vol 123 (2) ◽  
pp. 898-904 ◽  
Author(s):  
MARIA TERESA DE LOS FRAILES ◽  
LUCINDA CACICEDO ◽  
MARIA JESUS LORENZO ◽  
GUMERSINDO FERNANDEZ ◽  
FRANCO SANCHEZ-FRANCO
Keyword(s):  
Thyroid Hormone ◽  
Rat Brain ◽  
Brain Cells ◽  
Hormone Action ◽  
Cells In Culture ◽  
Thyroid Hormone Action ◽  
Fetal Rat ◽  
Fetal Rat Brain

Role of Locally Produced Growth Hormone-Releasing Factor in Somatostatin Regulation by Fetal Rat Brain Cells in Culture

1992 ◽  
Vol 55 (2) ◽  
pp. 221-229 ◽  
Author(s):  
Maria Teresa de los Frailes ◽  
Luanda Cacicedo ◽  
Gumersindo Fernandez ◽  
Rosa Maria Tolón ◽  
Maria Jesus Lorenzo ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Rat Brain ◽  
Brain Cells ◽  
Growth Hormone Releasing Factor ◽  
Cells In Culture ◽  
Fetal Rat ◽  
Fetal Rat Brain

Interactions between fetal rat brain cells and mature brain tissue in vivo and in vitro

1994 ◽  
Vol 20 (2) ◽  
pp. 130-143 ◽  
Author(s):  
K. Marienhagen ◽  
P.-H. Pedersen ◽  
A. J. A. Terzis ◽  
O. D. Laerum ◽  
H. Arnold ◽  
...  
Keyword(s):  
Rat Brain ◽  
Brain Tissue ◽  
Brain Cells ◽  
Mature Brain ◽  
Fetal Rat ◽  
Fetal Rat Brain

Chemically evoked release of an angiotensin-like peptide from fetal rat brain cells in culture

1986 ◽  
Vol 251 (1) ◽  
pp. C17-C22 ◽  
Author(s):  
J. M. Meyer ◽  
J. A. Weyhenmeyer
Keyword(s):  
Rat Brain ◽  
High Performance ◽  
Renin Angiotensin System ◽  
Brain Cells ◽  
Ang Ii ◽  
Sprague Dawley ◽  
Cells In Culture ◽  
Fetal Rat ◽  
Presynaptic Nerve Terminals ◽  
Fetal Rat Brain

Recent evidence has demonstrated that dissociated fetal rat brain cells in culture synthesize an angiotensin II (ANG II)-like peptide that shares common properties with authentic ANG II, suggesting that brain has a complete renin angiotensin system that is independent of peripheral substrates. Although ANG II has been postulated to function as a neurotransmitter/neuromodulator, the release of ANG II from presynaptic nerve terminals has not been established. To investigate the mechanism of ANG II release, brain cells from 20-day gestational age Sprague-Dawley rats were dissociated by mild trypsinization and grown in culture. The cells were maintained in serum-free medium for 5 days prior to experimental analysis. Cultured brain cells were challenged with 59 mM KCl in the presence or absence of 5 mM CaCl2, and the incubation medium was measured for the release of ANG II by radioimmunoassay and high-performance liquid chromatography. The data demonstrate that K+ stimulation results in a rapid and time-dependent release of ANG II-like peptide that is Ca2+ dependent. We have concluded that these findings are consistent with those for other neurotransmitter/neurohormone systems and therefore provide further support for the role of ANG II as a chemical transmitter in the brain.

Synthesis and Secretion of Vasoactive Intestinal Peptide and VIP-Prohormone by Fetal Rat Brain Cells in Culture

1988 ◽  
Vol 527 (1 Vasoactive In) ◽  
pp. 598-599 ◽  
Author(s):  
L. CACICEDO ◽  
M. J. LORENZO ◽  
M. T. DE LOS FRAILES ◽  
S. REICHLIN ◽  
F. SANCHEZ FRANCO
Keyword(s):  
Rat Brain ◽  
Vasoactive Intestinal Peptide ◽  
Brain Cells ◽  
Cells In Culture ◽  
Fetal Rat ◽  
Fetal Rat Brain
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