Cytogenetic analysis of in vitro fertilization (IVF) failures

1989 ◽  
Vol 81 (4) ◽  
pp. 367-370 ◽  
Author(s):  
M. H. E. C. Pieters ◽  
J. P. M. Geraedts ◽  
J. C. M. Dumoulin ◽  
J. L. H. Evers ◽  
M. Bras ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Cytogenetic Analysis ◽  
Vitro Fertilization

Triploidy after in vitro fertilization: Cytogenetic analysis of human zygotes and embryos

1992 ◽  
Vol 9 (1) ◽  
pp. 68-76 ◽  
Author(s):  
M. H. E. C. Pieters ◽  
J. C. M. Dumoulin ◽  
R. C. M. Ignoul-Vanvuchelen ◽  
M. Bras ◽  
J. L. H. Evers ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Cytogenetic Analysis ◽  
Vitro Fertilization ◽  
Human Zygotes

scholarly journals Balanced translocations 46, XY, t (8;17)(p23;q11) in brothers with azoospermia

2021 ◽  
Vol 7 (1) ◽  
pp. 091-093
Author(s):  
Mirela Mačkić-Đurović ◽  
Nejla Đikić ◽  
Dunja Rukavina
Keyword(s):  
In Vitro Fertilization ◽  
Human Health ◽  
Reciprocal Translocation ◽  
Cytogenetic Analysis ◽  
Genetic Factors ◽  
Diagnostic Analysis ◽  
Balanced Translocation ◽  
Vitro Fertilization ◽  
Balanced Translocations

Infertility is one of the most significant human health problems of the reproductive years. The causes of infertility are diverse and numerous-including non-genetic and genetic factors. A review of this case confirmed this. A balanced translocation was found in two siblings diagnosed with azoospermia. After being unable to conceive, the older brother and his wife had two in vitro fertilization (IVF) failed. At the same time, his younger brother and his wife had one IVF. After the cytogenetic analysis was performed in both pairs, it was shown that the cause of their infertility was the same balanced translocation in the brothers. The female showed a regular (46, XX) karyotype, whereas the male was found to carry balanced reciprocal translocation [46, XY, t(8;17)(p23;q11)]. This case support that cytogenetic analysis is still the first and basic diagnostic analysis of patients with azoospermia and other reproductive problems.

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