scholarly journals Tropical pancreatic diabetes in South India: heterogeneity in clinical and biochemical profile

Diabetologia ◽  
1985 ◽  
Vol 28 (4) ◽  
Author(s):  
V. Mohan ◽  
R. Mohan ◽  
L. Susheela ◽  
C. Snehalatha ◽  
G. Bharani ◽  
...  
Metabolism ◽  
1986 ◽  
Vol 35 (9) ◽  
pp. 814-817 ◽  
Author(s):  
Sathit Vannasaeng ◽  
Wannee Nitiyanant ◽  
Apichati Vichayanrat ◽  
Sirirat Ploybutr ◽  
Sumon Harnthong

Author(s):  
C S Yajnik ◽  
A Katrak ◽  
S V Kanitkar ◽  
S S Naik ◽  
V D'Souza ◽  
...  

Fifteen patients with tropical pancreatic diabetes syndrome (TPDS), 16 insulin-dependent diabetics (IDD), 27 non-insulin-dependent diabetics (NIDD) and 14 normal subjects, all from India, were investigated for markers of β-cell (C-peptide) and exocrine (immunoreactive trypsin; IRT) reserve. IRT and C-peptide concentrations were the lowest in TPDS, lower than normal in IDD, and not significantly different from normal in NIDDs. There was a highly significant correlation ( rs = 0·;D93; P < 0·;00001) between IRT and C-peptide (measured in 50% of patients and controls) concentrations when all diabetic groups were combined. Such a correlation was absent when TPDS patients were considered in isolation, largely because of the markedly low IRT concentration. Fourteen of 15 patients (93%) with TPDS had subnormal IRT concentrations, of which 11 had IRT values of less than 50 μg/L. These IRT values are similar to those previously reported in cystic fibrosis. Only 6 of 16 IDDs (38%) had subnormal IRT concentrations, of which only one was below 50 μg/L. These data suggest that exocrine pancreatic reserve is markedly diminished in TPDS and that a subnormal IRT concentration may be a useful biochemical marker for this form of diabetes.


Metabolism ◽  
1983 ◽  
Vol 32 (12) ◽  
pp. 1091-1092 ◽  
Author(s):  
V. Mohan ◽  
C. Snehalatha ◽  
A. Ramachandran ◽  
R. Jayashree ◽  
M. Viswanathan

2005 ◽  
Vol 9 (1) ◽  
pp. 63-67 ◽  
Author(s):  
Suresh Sankarasubbaiyan ◽  
Georgi Abraham ◽  
P Soundararajan ◽  
V Chandrasekaran ◽  
G Padma

1985 ◽  
Vol 103 (10) ◽  
pp. 1487-1489 ◽  
Author(s):  
R. Mohan ◽  
B. Rajendran ◽  
V. Mohan ◽  
A. Ramachandran ◽  
M. Viswanathan ◽  
...  

Diabetes Care ◽  
1987 ◽  
Vol 10 (4) ◽  
pp. 532-533 ◽  
Author(s):  
V. Mohan ◽  
R. Mohan ◽  
A. Ramachandran ◽  
C. Snehalatha ◽  
M. Viswanathan

Diabetologia ◽  
1985 ◽  
Vol 28 (9) ◽  
pp. 708-708 ◽  
Author(s):  
M. M. S. Ahuja

2020 ◽  
Vol 3 (6) ◽  
pp. 122-126
Author(s):  
Sathisha TG ◽  
Bhargavi S K ◽  
Riyaz Ahmad Kalaburgi ◽  
Shashiraj H K ◽  
Kavitha BS ◽  
...  

1985 ◽  
Vol 22 (2) ◽  
pp. 143-148 ◽  
Author(s):  
Viswanathan Mohan ◽  
Doraiswami Sreeram ◽  
Ambady Ramachandran ◽  
Moopil Viswanathan ◽  
Kalapathy Rama Iyer Doraiswamy

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