Modification of the 5′ untranslated leader region of the maize Activator element leads to increased activity in Arabidopsis

1994 ◽  
Vol 245 (5) ◽  
pp. 608-615 ◽  
Author(s):  
E. J. R. Lawson ◽  
S. R. Scofield ◽  
C. Sjodin ◽  
J. D. G. Jones ◽  
C. Dean
Keyword(s):  
Leader Region ◽  
Increased Activity ◽  
Untranslated Leader Region

The mutation bronze-mutable 4 derivative 6856 in maize is caused by the insertion of a novel 6.7-kilobase pair transposon in the untranslated leader region of the bronze-1 gene.

Genetics ◽  
1988 ◽  
Vol 120 (3) ◽  
pp. 779-790
Author(s):  
A S Klein ◽  
M Clancy ◽  
L Paje-Manalo ◽  
D B Furtek ◽  
L C Hannah ◽  
...  
Keyword(s):  
Gene Expression ◽  
Molecular Level ◽  
Specific Pattern ◽  
Leader Region ◽  
Base Pairs ◽  
Partial Duplication ◽  
Tissue Specific ◽  
Flanking Sequences ◽  
Untranslated Leader Region

Abstract The Ds-controlled allele, bz-m4 Derivative 6856 [bz-m4 D6856], is reported to have an altered temporal- and tissue-specific pattern of gene expression. We have cloned this allele and have characterized it at the molecular level. The mutation was caused by the insertion of a complex transposon-like structure 36 base pairs downstream from the Bz mRNA cap site. The insert is 6.7-kbp long. Ds elements, each approximately 2 kbp in length, are at both ends of the insert. The sequence between the Ds elements is a partial duplication of flanking sequences from the 3' end of the Bz gene. These data suggest that Ds initially inserted near the 3' end of the gene and mobilized adjacent sequences as it transposed.

A primary transcript in spinach chloroplasts that completely lacks a 5′ untranslated leader region

1990 ◽  
Vol 15 (1) ◽  
pp. 111-119 ◽  
Author(s):  
D. Clark Bennett ◽  
Sharon A. Rogers ◽  
Liang-Jwu Chen ◽  
Emil M. Orozco
Keyword(s):  
Leader Region ◽  
Primary Transcript ◽  
Spinach Chloroplasts ◽  
Untranslated Leader Region

Rhabdomyolysis in DOMS

1999 ◽  
Vol 38 (05) ◽  
pp. 164-168 ◽  
Author(s):  
Gloria Ruiz Hernandez ◽  
C. Sanchez Marchori ◽  
J. Munoz Moliner ◽  
C. Martinez Carsi
Keyword(s):  
Bone Scintigraphy ◽  
Previous History ◽  
Biochemical Studies ◽  
History Of ◽  
Increased Activity

SummaryA 26-year-old man with a previous history of external twin bursitis was remitted to our Department for a bone scintigraphy. Before the study, the patient performed an elevated number of intense sprints. Bone scintigraphy showed a bilaterally increased activity in both anterior rectum muscles suggesting rhabdomyolysis. Biochemical studies and MRT confirmed the diagnosis.

Increased Activity of Vitamin K-Dependent Clotting Factors in Human Hyperlipoproteinaemia – Association with Cholesterol and Triglyceride Levels

1977 ◽  
Vol 38 (02) ◽  
pp. 0465-0474 ◽  
Author(s):  
M Constantino ◽  
C Merskey ◽  
D. J Kudzma ◽  
M. B Zucker
Keyword(s):  
Vitamin K ◽  
Plasma Lipids ◽  
Coagulation Factors ◽  
Clotting Factor ◽  
Factor X ◽  
Clotting Factors ◽  
Blood Coagulation Factors ◽  
Cholesterol Levels ◽  
Type V ◽  
Increased Activity

SummaryLevels of blood coagulation factors, cholesterol and triglyceride were measured in human plasma. Prothrombin was significantly elevated in type Ha hyperlipidaemia; prothrombin and factors VII, IX and X in type lib; and prothrombin and factors VII and IX in type V. Multiple regression analysis showed significant correlation between the levels of these plasma lipids and the vitamin K-dependent clotting factors (prothrombin, factors VII, IX and X). Higher cholesterol levels were associated with higher levels of prothrombin and factor X while higher triglyceride levels were associated with higher levels of these as well as factors VII and IX. Prothrombin showed a significant cholesterol-triglyceride interaction in that higher cholesterol levels were associated with higher prothrombin levels at all levels of triglyceride, with the most marked effects in subjects with higher triglyceride levels. Higher prothrombin levels were noted in subjects with high or moderately elevated (but not low) cholesterol levels. Ultracentrifugation of plasma in a density of 1.21 showed activity for prothrombin and factors VII and X only in the lipoprotein-free subnatant fraction. Thus, a true increase in clotting factor protein was probably present. The significance of the correlation between levels of vitamin K-dependent clotting factors and plasma lipids remains to be determined.

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