Prenatal diagnosis of X-linked choroideremia with mental retardation, associated with a cytologically detectable X-chromosome deletion

1987 ◽  
Vol 75 (3) ◽  
pp. 286-290 ◽  
Author(s):  
S. V. Hodgson ◽  
M. E. Robertson ◽  
C. N. Fear ◽  
J. Goodship ◽  
S. Malcolm ◽  
...  
Keyword(s):  
Mental Retardation ◽  
Prenatal Diagnosis ◽  
X Chromosome ◽  
Chromosome Deletion

scholarly journals 761 MULTIPLE SIBLING MENTAL RETARDATION AND THE IMPACT OF THE FRAGILE X CHROMOSOME

1981 ◽  
Vol 15 ◽  
pp. 569-569 ◽  
Author(s):  
Lawrence R Shapiro ◽  
Murray D Kuhr ◽  
Patrick L Wilmot
Keyword(s):  
Mental Retardation ◽  
X Chromosome ◽  
Fragile X ◽  
The Impact

scholarly journals Differential DNA Methylation as a Tool for Noninvasive Prenatal Diagnosis (NIPD) of X Chromosome Aneuploidies

2010 ◽  
Vol 12 (6) ◽  
pp. 797-807 ◽  
Author(s):  
Floriana Della Ragione ◽  
Paola Mastrovito ◽  
Ciro Campanile ◽  
Anna Conti ◽  
Elisavet A. Papageorgiou ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Prenatal Diagnosis ◽  
X Chromosome ◽  
Noninvasive Prenatal Diagnosis

Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse

1991 ◽  
Vol 56 (3-4) ◽  
pp. 137-143 ◽  
Author(s):  
B.M. Cattanach ◽  
C. Rasberry ◽  
E.P. Evans ◽  
L. Dandolo ◽  
M.C. Simmler ◽  
...  
Keyword(s):  
X Chromosome ◽  
Molecular Evidence ◽  
Chromosome Deletion ◽  
Testicular Feminization

A Role for the X Chromosome in Sex Differences in Variability in General Intelligence?

2009 ◽  
Vol 4 (6) ◽  
pp. 598-611 ◽  
Author(s):  
Wendy Johnson ◽  
Andrew Carothers ◽  
Ian J. Deary
Keyword(s):  
Sex Differences ◽  
Mental Retardation ◽  
X Chromosome ◽  
Cognitive Abilities ◽  
Population Distribution ◽  
Population Variation ◽  
General Intelligence ◽  
Substantial Evidence ◽  
Normal Distributions ◽  
Intellectual Abilities

There is substantial evidence that males are more variable than females in general intelligence. In recent years, researchers have presented this as a reason that, although there is little, if any, mean sex difference in general intelligence, males tend to be overrepresented at both ends of its overall distribution. Part of the explanation could be the presence of genes on the X chromosome related both to syndromal disorders involving mental retardation and to population variation in general intelligence occurring normally. Genes on the X chromosome appear overrepresented among genes with known involvement in mental retardation, which is consistent with a model we developed of the population distribution of general intelligence as a mixture of two normal distributions. Using this model, we explored the expected ratios of males to females at various points in the distribution and estimated the proportion of variance in general intelligence potentially due to genes on the X chromosome. These estimates provide clues to the extent to which biologically based sex differences could be manifested in the environment as sex differences in displayed intellectual abilities. We discuss these observations in the context of sex differences in specific cognitive abilities and evolutionary theories of sexual selection.

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