Cytological localization of the maternal effect gene, tuh-1, in Drosophila melanogaster

1976 ◽  
Vol 146 (2) ◽  
pp. 189-190 ◽  
Author(s):  
Jagdeesh Pyati
Keyword(s):  
Drosophila Melanogaster ◽  
Maternal Effect ◽  
Maternal Effect Gene ◽  
Cytological Localization ◽  
Effect Gene

abnormal chromatin (abc), a maternal-effect locus in Drosophila melanogaster

1991 ◽  
Vol 98 (2) ◽  
pp. 233-243 ◽  
Author(s):  
K.B. Vessey ◽  
R.L. Ludwiczak ◽  
A.S. Briot ◽  
E.M. Underwood
Keyword(s):  
Drosophila Melanogaster ◽  
Maternal Effect ◽  
Chromosome Structure ◽  
Nuclear Division ◽  
Embryonic Cell ◽  
Female Sterility ◽  
Chromosome 2 ◽  
Maternal Effect Gene ◽  
Embryonic Cell Cycle ◽  
Effect Gene

Mutations in the maternal-effect gene abnormal chromatin (abc) in Drosophila melanogaster result in a variety of defects involving nuclear replication/division. Three recessive alleles of this gene, which maps near 51F on chromosome 2, all result in female sterility. They cause slower embryonic development that is usually abnormal from the earliest nuclear divisions and arrested by the sixth one. Nuclei tend to be large and erratically distributed, some intensely staining. Mitotic asynchrony is common. Few embryos reach the gastrula stage and none hatch. With the weakest allele, fsPL, bridges between nuclei are common; abnormal chromatin clumps that resemble yolk nuclei occur before the other nuclei reach the surface; and spindle anomalies and DNA wads with numerous centrosomes are seen. Females with the stronger alleles, fsA5 and fs27, lay fewer eggs and a smaller proportion of embryos reach blastoderm; developmental arrest occurs earlier, usually with several large nuclei distributed along the length of the embryo. Chorion defects occur in all three mutants. Mitotic asynchrony, nuclear bridging, endoreduplication and nuclear behavior aberrant from the first division suggest that the abc gene product operates in DNA replication/nuclear division. Larval (homozygous F1) neuroblast chromosome structure and mitotic indices are normal, indicating that any mitotic function is strictly maternal, i.e. abc is not a general mitotic gene. Thus abc is one of a few known genes with a maternal effect that appears to function in the embryonic cell cycle.

scholarly journals DOSAGE OF THE MATERNAL EFFECT GENE ASSOCIATED WITH THE TUMOROUS-HEAD ABNORMALITY IN DROSOPHILA MELANOGASTER

Genetics ◽  
1972 ◽  
Vol 72 (2) ◽  
pp. 377-380
Author(s):  
R M Siervogel
Keyword(s):  
Drosophila Melanogaster ◽  
Gene Product ◽  
Maternal Effect ◽  
Specific Gene ◽  
Maternal Effect Gene ◽  
Effect Gene

ABSTRACT The penetrance of tuh-3 observed in the progeny of triploids with two doses of tuh-1 was not statistically different from that occurring in the progeny of their diploid sisters with two doses. A higher penetrance was observed in the progeny of triploids with three doses of tuh-1 than in the progeny of their diploid sisters with two doses. These observations suggest that the maternal effect responsible for increasing the penetrance of tuh-3, the gene causing the tumorous-head abnormality, is caused by a specific gene product of tuh-1, the maternal-effect allele. In addition there is probably a maternal-effect threshold, lying between amounts produced by one and two doses of tuh-1, below which no increased penetrance of tuh-3 is observed.

scholarly journals Maternal-effect gene Ces5/Ooep/Moep19/Floped is essential for oocyte cytoplasmic lattice formation and embryonic development at the maternal-zygotic stage transition

2010 ◽  
Vol 15 (8) ◽  
pp. 813-828 ◽  
Author(s):  
Fumi Tashiro ◽  
Masami Kanai-Azuma ◽  
Satsuki Miyazaki ◽  
Masahiro Kato ◽  
Tomofumi Tanaka ◽  
...  
Keyword(s):  
Embryonic Development ◽  
Maternal Effect ◽  
Maternal Effect Gene ◽  
Stage Transition ◽  
Lattice Formation ◽  
Effect Gene

scholarly journals The “first” maternal effect gene

2012 ◽  
Vol 79 (10) ◽  
pp. Fm i-Fm i
Author(s):  
Gary M. Wessel
Keyword(s):  
Maternal Effect ◽  
Maternal Effect Gene ◽  
Effect Gene

scholarly journals Molecular cloning and expression of bovine nucleoplasmin 2 (NPM2): a maternal effect gene regulated by miR-181a

2011 ◽  
Vol 9 (1) ◽  
pp. 40 ◽  
Author(s):  
Brandon M Lingenfelter ◽  
Swamy K Tripurani ◽  
Jyothsna Tejomurtula ◽  
George W Smith ◽  
Jianbo Yao
Keyword(s):  
Molecular Cloning ◽  
Maternal Effect ◽  
Cloning And Expression ◽  
Maternal Effect Gene ◽  
Effect Gene
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