Exercise training mode affects the hemodynamic responses to lower body negative pressure in women

1996 ◽  
Vol 73 (1-2) ◽  
pp. 169-174 ◽  
Author(s):  
W. D. Franke ◽  
K. A. Taylor
Maturitas ◽  
2017 ◽  
Vol 103 ◽  
pp. 91
Author(s):  
Amanda Q.X. Nio ◽  
Eric J. Stöhr ◽  
Samantha Rogers ◽  
Rachel Mynors-Wallis ◽  
Jane M. Black ◽  
...  

2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Brian Lora ◽  
Gaia Giuriato ◽  
Tawn Tomasi ◽  
Meaghan Lynch ◽  
Jack Schickler ◽  
...  

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Carmen Hinojosa‐Laborde ◽  
Robert Shade ◽  
Gary Muniz ◽  
Cassondra Bauer ◽  
Victor Convertino

1982 ◽  
Vol 14 (2) ◽  
pp. 157
Author(s):  
Peter B. Raven ◽  
Debbie Rohm-Young ◽  
Steven Meyer ◽  
Robert Eaves

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Blair David Johnson ◽  
Noud Helmond ◽  
Timothy B. Curry ◽  
Victor A. Convertino ◽  
Michael J. Joyner

Author(s):  
Alexander J. Rosenberg ◽  
Victoria L. Kay ◽  
Garen K. Anderson ◽  
Justin D. Sprick ◽  
Caroline A. Rickards

Lower body negative pressure (LBNP) elicits central hypovolemia, and has been used to simulate the cardiovascular and cerebrovascular responses to hemorrhage in humans. LBNP protocols commonly employ progressive stepwise reductions in chamber pressure for specific time periods. However, continuous ramp LBNP protocols have also been utilized to simulate the continuous nature of most bleeding injuries. The aim of this study was to compare tolerance and hemodynamic responses between these two LBNP profiles. Healthy human subjects (N=19; age, 27±4 y; 7F/12M) completed a 1) step LBNP protocol (5-min steps), and; 2) continuous ramp LBNP protocol (3 mmHg/min), both to presyncope. Heart rate (HR), mean arterial pressure (MAP), stroke volume (SV), middle and posterior cerebral artery velocity (MCAv and PCAv), cerebral oxygen saturation (ScO2), and end-tidal CO2 (etCO2) were measured. LBNP tolerance, via the cumulative stress index (CSI, summation of chamber pressure*time at each pressure), and hemodynamic responses were compared between the two protocols. The CSI (Step: 911±97 mmHg*min vs. Ramp: 823±83 mmHg*min; P=0.12) and the magnitude of central hypovolemia (%Δ SV, Step: -54.6±2.6 % vs. Ramp: -52.1±2.8 %; P=0.32) were similar between protocols. While there were no differences between protocols for the maximal %Δ HR (P=0.88), the %Δ MAP during the step protocol was attenuated (P=0.05), and the reductions in MCAv, PCAv, ScO2, and etCO2 were greater (P≤0.08) when compared with the ramp protocol at presyncope. These results indicate that when comparing cardiovascular responses to LBNP across different laboratories, the specific pressure profile must be considered as a potential confounding factor.


2004 ◽  
Vol 97 (3) ◽  
pp. 925-929 ◽  
Author(s):  
J. P. Hernandez ◽  
W. D. Franke

Aging and chronic exercise training influence leg venous compliance. Venous compliance affects responses to an orthostatic stress; its effect on tolerance to maximal lower body negative pressure (LBNP) in the elderly is unknown. The purpose of this study was to determine the influence of age and fitness, a surrogate measure of exercise training, on calf venous compliance and tolerance to maximal LBNP in men and women. Forty participants, 10 young fit (YF; age = 22.6 ± 0.5 yr, peak oxygen uptake = 57.1 ± 2.0 ml·kg−1·min−1), 10 young unfit (YU; 23.1 ± 1.0 yr, 41.1 ± 2.0 ml·kg−1·min−1), 10 older fit (OF; 73.9 ± 2.0 yr, 39.0 ± 2.0 ml·kg−1·min−1), and 10 older unfit (OU; 70.9 ± 1.6 yr, 27.1 ± 2.0 ml·kg−1·min−1), underwent graded LBNP to presyncope or 4 min at −100 mmHg. By utilizing venous occlusion plethysmography, calf venous compliance was determined by using the first derivative of the pressure-volume relation during cuff pressure reduction. We found that the more fit groups had greater venous compliance than their unfit peers ( P < 0.05) as did the young groups compared with their older peers ( P < 0.05) such that OU < YU = OF < YF. LBNP tolerance did not differ between groups. In conclusion, these data suggest that aging reduces, and chronic exercise increases, venous compliance. However, these data do not support a significant influence of venous compliance on LBNP tolerance.


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