Synergistic effect of 3?-deoxyadenosine N 1-oxide and adenosine deaminase inhibitors on growth of Ehrlich ascites tumor cells in vivo

1988 ◽  
Vol 21 (1) ◽  
Author(s):  
KarstenRaml�v Svendsen ◽  
Kay Overgaard-Hansen ◽  
Sune Frederiksen
Keyword(s):  
Synergistic Effect ◽  
Adenosine Deaminase ◽  
Tumor Cells ◽  
Ehrlich Ascites Tumor ◽  
Ehrlich Ascites Tumor Cells ◽  
Ascites Tumor ◽  
Ehrlich Ascites

N-Substituted-2-butyl-5-chloro-3H-imidazole-4-carbaldehyde Derivatives as Anti-tumor Agents Against Ehrlich Ascites tumor Cells In Vivo

2007 ◽  
Vol 3 (3) ◽  
pp. 269-276 ◽  
Author(s):  
C. Anil Kumar ◽  
S. Nanjunda Swamy ◽  
S. L. Gaonkar ◽  
Basappa ◽  
Bharathi P. Salimath ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Ehrlich Ascites Tumor ◽  
Ehrlich Ascites Tumor Cells ◽  
Ascites Tumor ◽  
Ehrlich Ascites

Relative importance of alternative pathways of purine nucleotide biosynthesis in Ehrlich ascites tumor cells in vivo

1976 ◽  
Vol 54 (4) ◽  
pp. 341-349 ◽  
Author(s):  
Camilla M. Smith ◽  
J. Frank Henderson
Keyword(s):  
Tumor Cells ◽  
Ehrlich Ascites Tumor ◽  
Relative Importance ◽  
Purine Nucleotide ◽  
Ehrlich Ascites Tumor Cells ◽  
Ascites Tumor ◽  
Alternative Pathways ◽  
Ehrlich Ascites ◽  
In Cells

Several alternative pathways of purine nucleotide synthesis coexist in cells and the relative importance of each pathway for maintaining purine nucleotide concentrations in cells has been studied. Specific inhibitors were used to block these synthetic routes in Ehrlich ascites tumor cells in vivo and the effect of inhibiting each pathway was evaluated by measuring intracellular purine nucleotide concentrations by high-speed liquid chromatography. The results of this study indicate that adenosine triphosphate and guanosine triphosphate concentrations of Ehrlich ascites tumor cells are maintained primarily by purine biosynthesis de novo although other pathways do make significant contributions.

Synergistic Effect of Ammonium and Potassium Ions on Pyruvate Kinase from Ehrlich Ascites Tumor Cells

Enzyme ◽  
1986 ◽  
Vol 35 (1) ◽  
pp. 34-41 ◽  
Author(s):  
J. s. Olavarria ◽  
E. Artacho ◽  
F. Sánchez ◽  
P. Martinez ◽  
I. Núñez de Castro
Keyword(s):  
Synergistic Effect ◽  
Tumor Cells ◽  
Pyruvate Kinase ◽  
Ehrlich Ascites Tumor ◽  
Potassium Ions ◽  
Ehrlich Ascites Tumor Cells ◽  
Ascites Tumor ◽  
Ehrlich Ascites
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