Tissue polypeptide antigen (TPA), some cytokeratins and epithelial membrane antigen (EMA) in normal, inflamed and malignant urothelium

1987 ◽  
Vol 15 (4) ◽  
Author(s):  
B.E. Carbin ◽  
V.P. Collins ◽  
P. Ekman
Keyword(s):  
Epithelial Membrane Antigen ◽  
Tissue Polypeptide Antigen

Primary Intrapulmonary Thymomas: Case Report and Review of the Literature

2009 ◽  
Vol 37 (4) ◽  
pp. 1252-1257 ◽  
Author(s):  
L Gong ◽  
Y-H Li ◽  
X-L He ◽  
Q Wang ◽  
L Yao ◽  
...  
Keyword(s):  
Epithelial Membrane Antigen ◽  
Immunohistochemical Analysis ◽  
Lung Tumour ◽  
Review Of The Literature ◽  
Malignant Tumours ◽  
Pathological Characteristics ◽  
Immunological Phenotype ◽  
Type A Thymoma

Primary intrapulmonary thymomas (PIT), which are intrapulmonary tumours without an associated mediastinal component, are very rare; only 29 cases of PIT have been described in the literature since 1951. This report presents a case of PIT in a 59-year old Chinese woman with a type A thymoma (including its pathogenesis, clinical pathological characteristics, immunological phenotype, treatment and prognosis), in the context of a review of the current literature. The origin of thymomas in this unusual location remains unknown. In this case, immunohistochemical analysis demonstrated that the epithelial component was strongly positive for cytokeratin and focally reactive for epithelial membrane antigen. It is concluded that PIT should be considered when the histopathological appearance of a lung tumour is not typical of other pulmonary neoplasms. Complete resection appears sufficient in non-malignant tumours, while in cases of partial resection or malignancy, adjuvant radiotherapy should be considered. Long-term regular clinical follow-up is also warranted, due to the risk of late local recurrence.

Sarcomatoid Carcinoma of the Small Intestine: A Case Report and Review of the Literature

2004 ◽  
Vol 128 (8) ◽  
pp. 918-921
Author(s):  
Michelle Reid-Nicholson ◽  
Muhammed Idrees ◽  
Giorgio Perino ◽  
Prodromos Hytiroglou
Keyword(s):  
Small Bowel ◽  
Epithelial Membrane Antigen ◽  
Spindle Cell ◽  
English Literature ◽  
Sarcomatoid Carcinoma ◽  
Giant Cells ◽  
Intestinal Wall ◽  
Cytokeratin 20 ◽  
Spindle Cells ◽  
Immunohistochemical Stains

Abstract Sarcomatoid carcinoma of the small bowel is rare; to our knowledge, 19 cases have been reported to date in the English literature under several names. We report an additional case occurring in the jejunum of a 55-year-old man. The tumor was a polypoid 7.5-cm mass, which infiltrated the full thickness of the intestinal wall and the serosa of an adhesed loop of small bowel. On microscopic examination, the neoplasm was composed of sheets of spindle cells; focally, an anaplastic component was present, including tumor giant cells with bizarre nuclei. On immunohistochemical stains, tumor cells were positive for cytokeratin 7, cytokeratin AE1/AE3, vimentin, and focally, epithelial membrane antigen. No staining for cytokeratin 20 was found. Sarcomatoid carcinoma must be kept in mind in the differential diagnosis of malignant spindle cell tumors of the small bowel. As consensus regarding the terminology of these rare tumors is being reached, immunohistochemical stains are essential for accurate diagnosis.

Expression of Vimentin and Epithelial Membrane Antigen in Human Malignant Lymphomas

1990 ◽  
Vol 40 (8) ◽  
pp. 581-587
Author(s):  
Ashit Baran Sarker ◽  
Tadaatsu Akagi ◽  
Tadashi Yoshino ◽  
Yoshihiko Hoshida ◽  
Kiyoshi Takahashi ◽  
...  
Keyword(s):  
Epithelial Membrane Antigen ◽  
Malignant Lymphomas
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