Mannose inhibition of Escherichia coli adherence to urinary bladder epithelium: Comparison with yeast agglutination

1985 ◽  
Vol 13 (2) ◽  
Author(s):  
M.R. Ruggieri ◽  
P.M. Hanno ◽  
R.M. Levin
Keyword(s):  
Escherichia Coli ◽  
Urinary Bladder ◽  
Bladder Epithelium

scholarly journals Correction: Moxley, R.A., et al. Intimate Attachment of Escherichia coli O157:H7 to Urinary Bladder Epithelium in the Gnotobiotic Piglet Model. Microorganisms 2020, 8, 263

2020 ◽  
Vol 8 (12) ◽  
pp. 2016
Author(s):  
Rodney A. Moxley ◽  
Tom W. Bargar ◽  
Stephen D. Kachman ◽  
Diane R. Baker ◽  
David H. Francis
Keyword(s):  
Escherichia Coli ◽  
Urinary Bladder ◽  
Escherichia Coli O157 ◽  
Bladder Epithelium ◽  
Gnotobiotic Piglet

The authors wish to make the following corrections to this paper [...]

scholarly journals Intimate Attachment of Escherichia coli O157:H7 to Urinary Bladder Epithelium in the Gnotobiotic Piglet Model

2020 ◽  
Vol 8 (2) ◽  
pp. 263 ◽  
Author(s):  
Rodney A. Moxley ◽  
Tom W. Bargar ◽  
Stephen D. Kachman ◽  
Diane R. Baker ◽  
David H. Francis
Keyword(s):  
Escherichia Coli ◽  
Urinary Bladder ◽  
Enterohemorrhagic Escherichia Coli ◽  
Post Inoculation ◽  
Bladder Epithelium ◽  
Fecal Shedding ◽  
E Coli ◽  
Gnotobiotic Piglet ◽  
Immunohistochemical Evidence ◽  
Tract Infections

Enterohemorrhagic Escherichia coli (EHEC), a pathogenic subset of Shiga toxin-producing E. coli (STEC), is an important cause of hemorrhagic colitis and hemolytic–uremic syndrome (HUS), and a rare cause of urinary tract infections (UTIs) with associated HUS. EHEC strains attach intimately to intestinal epithelium with formation of actin pedestals (attaching-effacing (A/E) lesions); however, the mechanism of EHEC attachment to the uroepithelium is unknown. We conducted a retrospective study on archived urinary bladder specimens from gnotobiotic piglets that naturally developed cystitis associated with EHEC O157:H7 infection following oral inoculation and fecal shedding. Paraffin-embedded bladder tissues from three piglets with cystitis and immunohistochemical evidence of EHEC O157:H7 adherence to the uroepithelium were processed for and examined by transmission electron microscopy. EHEC O157:H7 bacteria were found in one of three piglets, intimately attached to pedestals on the apical surfaces of the superficial urothelium (umbrella cells). Cystitis was significantly associated with the length of survival of the piglets post-inoculation (p = 0.0339; estimated odds ratio = 2.6652). This is the first report of E. coli causing A/E-like lesions in the uroepithelium, and also evidence of the utility of the gnotobiotic piglet as a model for studies of the pathogenesis of EHEC UTIs.

Initial effects of cyclophosphamide on urinary bladder epithelium in the rat

Pathology ◽  
1974 ◽  
Vol 6 (4) ◽  
pp. 343-350 ◽  
Author(s):  
Mary E. Schultz ◽  
Michael W. Weldon
Keyword(s):  
Urinary Bladder ◽  
Bladder Epithelium

scholarly journals An infection-induced RhoB-Beclin 1-Hsp90 complex enhances clearance of uropathogenic Escherichia coli

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Chunhui Miao ◽  
Mingyu Yu ◽  
Geng Pei ◽  
Zhenyi Ma ◽  
Lisong Zhang ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Treatment Strategies ◽  
Uropathogenic Escherichia Coli ◽  
Beclin 1 ◽  
Host Cells ◽  
Infection Model ◽  
Intracellular Bacteria ◽  
Bladder Epithelium ◽  
Binding Residue

AbstractHost cells use several anti-bacterial pathways to defend against pathogens. Here, using a uropathogenic Escherichia coli (UPEC) infection model, we demonstrate that bacterial infection upregulates RhoB, which subsequently promotes intracellular bacteria clearance by inducing LC3 lipidation and autophagosome formation. RhoB binds with Beclin 1 through its residues at 118 to 140 and the Beclin 1 CCD domain, with RhoB Arg133 being the key binding residue. Binding of RhoB to Beclin 1 enhances the Hsp90-Beclin 1 interaction, preventing Beclin 1 degradation. RhoB also directly interacts with Hsp90, maintaining RhoB levels. UPEC infections increase RhoB, Beclin 1 and LC3 levels in bladder epithelium in vivo, whereas Beclin 1 and LC3 levels as well as UPEC clearance are substantially reduced in RhoB+/− and RhoB−/− mice upon infection. We conclude that when stimulated by UPEC infections, host cells promote UPEC clearance through the RhoB-Beclin 1-HSP90 complex, indicating RhoB may be a useful target when developing UPEC treatment strategies.

A method of isolation of apical membranous sheets from frog urinary bladder epithelium by stripping with gelatin

1989 ◽  
Vol 66 (1-2) ◽  
pp. 99-106
Author(s):  
Pierre Favard ◽  
Nina Favard ◽  
Qian Long Zhu ◽  
Jacques Bourguet ◽  
Jean-Pierre Lechaire
Keyword(s):  
Urinary Bladder ◽  
Frog Urinary Bladder ◽  
Bladder Epithelium

1145 SLOW-CYCLING CELLS OF THE URINARY BLADDER EPITHELIUM

2013 ◽  
Vol 189 (4S) ◽  
Author(s):  
Sara Colopy ◽  
Dale Bjorling ◽  
William Mulligan ◽  
Wade Bushman
Keyword(s):  
Urinary Bladder ◽  
Bladder Epithelium ◽  
Slow Cycling

Membrane differentiation in the golgi apparatus of mammalian urinary bladder epithelium

1982 ◽  
Vol 203 (4) ◽  
pp. 429-440 ◽  
Author(s):  
Joseph Alroy ◽  
Frederick B. Merk ◽  
D. James Morré ◽  
Ronald S. Weinstein
Keyword(s):  
Urinary Bladder ◽  
Golgi Apparatus ◽  
Bladder Epithelium ◽  
Membrane Differentiation
Sign in / Sign up

Export Citation Format

Share Document