Early detection of infantile endocarditis by gallium ? 67 scintigraphy

1989 ◽  
Vol 15 (4) ◽  
pp. 219-221 ◽  
Author(s):  
Ruth Hardoff ◽  
Anthony S. Luder ◽  
Abraham Lorber ◽  
Leslie Dembo
Keyword(s):  
Author(s):  
D. C. Swartzendruber ◽  
Norma L. Idoyaga-Vargas

The radionuclide gallium-67 (67Ga) localizes preferentially but not specifically in many human and experimental soft-tissue tumors. Because of this localization, 67Ga is used in clinical trials to detect humar. cancers by external scintiscanning methods. However, the fact that 67Ga does not localize specifically in tumors requires for its eventual clinical usefulness a fuller understanding of the mechanisms that control its deposition in both malignant and normal cells. We have previously reported that 67Ga localizes in lysosomal-like bodies, notably, although not exclusively, in macrophages of the spocytaneous AKR thymoma. Further studies on the uptake of 67Ga by macrophages are needed to determine whether there are factors related to malignancy that might alter the localization of 67Ga in these cells and thus provide clues to discovering the mechanism of 67Ga localization in tumor tissue.


2001 ◽  
Vol 120 (5) ◽  
pp. A606-A606
Author(s):  
Y MORII ◽  
T YOSHIDA ◽  
T MATSUMATA ◽  
T ARITA ◽  
K SHIMODA ◽  
...  

2004 ◽  
Vol 171 (4S) ◽  
pp. 481-481
Author(s):  
Ravery V. Vincent ◽  
Chautard D. Denis ◽  
Arnauld A. Villers ◽  
Laurent Boccon Gibbod

2003 ◽  
Vol 2 (1) ◽  
pp. 136
Author(s):  
C MEUNE ◽  
C GIRAUDEAU ◽  
H BECANE ◽  
O PASCAL ◽  
P LAFORET ◽  
...  

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