The skeleton in congenital, generalized lipodystrophy: evaluation using whole-body radiographic surveys, magnetic resonance imaging and technetium-99m bone scintigraphy

1992 ◽  
Vol 21 (6) ◽  
Author(s):  
JamesL. Fleckenstein ◽  
A. Garg ◽  
F.J. Bonte ◽  
M.F. Vuitch ◽  
R.M. Peshock
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Bone Scintigraphy ◽  
Whole Body ◽  
Resonance Imaging ◽  
Congenital Generalized Lipodystrophy ◽  
Technetium 99M

scholarly journals Magnetic resonance imaging and bone scintigraphy in bone metastasis detection: A comparative study

2010 ◽  
Vol 67 (6) ◽  
pp. 453-458 ◽  
Author(s):  
Silvija Lucic ◽  
Katarina Nikoletic ◽  
Andrea Peter ◽  
Milos Lucic ◽  
Dusan Jovanovic
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Bone Metastasis ◽  
Bone Scintigraphy ◽  
Regions Of Interest ◽  
Diagnostic Methods ◽  
Whole Body ◽  
Resonance Imaging ◽  
Mutual Correlation ◽  
Diagnostic Potential

Background/Aim. Bone scintigraphy is well-known method for the detection of neoplastic lesions with a high sensitivity and, at the same time, a lower specificity. On the other hand magnetic resonance imaging (MRI) is previously established noninvasive imaging method regarding its diagnostic specificity. The aim of this study was to determine the possibilities and to correlate two different diagnostic methods - bone scintigraphy and MRI in the detection of bone metastasis in the spine and pelvic bones. Methods. A total of 123 patients who underwent both bone scintigraphy and spine and pelvic MRI on 1.5 T MR imager were enrolled in this study. Scans were subsequently analyzed in total and divided in regions of interest (cervical, upper, middle and lower thoracic, upper and lower lumbar and pelvic region, which includes sacral spinal segment); afterwards the total number of 585 matching regions were compared and statistically analyzed. Results. The statistical analysis demonstrated significant correlation between the findings of both methods in total. Divided by regions of interest, significant degrees of correlation were demonstrated in all of them, except in the cervical spine region where the r-value was in the range of low correlation. Conclusion. Having a high mutual correlation, bone scintigraphy and MRI are to be considered as the complementary diagnostic methods in the detection of bone metastases. Still, increased diagnostic potential of MRI may highlights negative bone scintigraphy findings in the patients with solitary metastatic lesions or diffuse vertebral infiltration. Advances in the bone scintigraphy (single photon emission tomography - SPECT, SPECTcomputed tomography - SPECT-CT) and MRI (whole body MRI, diffusion MRI), make it possible the diagnostic potential of both methods will result in a further improvement in bone metastasis detection.

Whole-body magnetic resonance imaging for detecting bone metastases: comparison with bone scintigraphy

2008 ◽  
Vol 113 (8) ◽  
pp. 1157-1170 ◽  
Author(s):  
G. Cascini ◽  
C. Falcone ◽  
C. Greco ◽  
B. Bertucci ◽  
S. Cipullo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Bone Metastases ◽  
Bone Scintigraphy ◽  
Whole Body ◽  
Resonance Imaging ◽  
Body Magnetic Resonance Imaging

scholarly journals Extra-osseous 99mTc methylene diphosphonate uptake detected enlargement of the knee joint in patient with polyarthritis

2017 ◽  
Vol 5 ◽  
pp. 2050313X1774182
Author(s):  
Maria Grazia Caprio ◽  
Mariarosaria Manganelli ◽  
Simona Limone ◽  
Massimiliano Sorbillo ◽  
Mario Quarantelli ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Soft Tissue ◽  
Bone Scintigraphy ◽  
Soft Tissues ◽  
Whole Body ◽  
Magnetic Resonance Imaging Scan ◽  
Resonance Imaging ◽  
Methylene Diphosphonate ◽  
Depth Analysis

Bone scintigraphy is a nuclear scanning test used to find abnormalities in the skeleton. Certain abnormal processes involving soft tissues can also cause skeletal accumulation of radiotracer during bone scintigraphy. We present a case of periarticular knee soft tissue 99mTc methylene diphosphonate uptake in a patient with asymmetric polyarthritis. A 33-year-old patient with asymmetric polyarthritis, skin lesions and joint pain underwent bone scintigraphy. Total body examination showed an extra-osseous uptake in periarticular soft tissue of knees joints. A detailed history checkup, physical examination and laboratory tests were carried out to understand the link between the extra-osseous uptake and the phosphonate binding in periarticular soft tissue. To improve the anatomical description of the soft tissue of the knees and to clarify the nature of the extra-skeletal 99mTc methylene diphosphonate uptake, magnetic resonance imaging scan was performed. 99mTc-labeled phosphonate binding has been reported in a number of extra-osseous conditions, but to our knowledge, there are a few cases showing bone tracer uptake in polyarthritis. In polyarthritic patients, whole-body bone scintigraphy were useful in examining the whole joints and detecting possible dubious extra-osseous uptake; in fact, it is able to select subjects who require further in-depth analysis, for example, magnetic resonance imaging.

scholarly journals Detection of Prostate Cancer Metastasis by Whole Body Magnetic Resonance Imaging Combined with Bone Scintigraphy and PSA Levels

2016 ◽  
Vol 40 (5) ◽  
pp. 1052-1062 ◽  
Author(s):  
Hengqing An ◽  
Ning Tao ◽  
Jia Li ◽  
Yonghui Guan ◽  
Wenguang Wang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
Prostate Specific Antigen ◽  
Bone Scintigraphy ◽  
Specific Antigen ◽  
Whole Body ◽  
Resonance Imaging ◽  
Body Magnetic Resonance Imaging ◽  
Psa Nadir

Background/Aims: The combined role of whole-body magnetic resonance imaging (WB-MRI), bone scintigraphy and prostate specific antigen (PSA) were considered in predicting metastases and prognosis of prostate cancer (PCa). Methods: Totally 38 PCa patients underwent WB-MRI, bone scintigraphy and PSA detections, and 34 benign prostate hyperplasia (BPH) patients were checked with PSA. Pearson correlations were performed to determine associations among PSA, apparent diffusion coefficient (ADC) and Gleason scoring. Specificity and sensitivity were for comparison of diagnostic accuracies. Patients' baseline PSA, PSA nadir and time to the prostate-specific antigen nadir (TTPN) were analyzed, and Kaplan-Meier survival curves were also established. Results: ADC values were negatively correlated with PSA levels (rs = -0.389, P = 0.016) and Gleason scores (rs = -0.432, P = 0.006), while PSA levels were positively correlated with Gleason scoring (rs = 0.493, P = 0.002). Diagnostic efficacy of whole body-diffusion weighted imaging (WB-DWI) combined with PSA seemed the most favorable, and bone scintigraphy was advantageous in identifying bone metastasis. PSA levels (> 61.60 µg/L), Gleason scores (> 6) and ADC (< 0.81 × 10-3 mm2/s) could all predict pessimistic prognosis (HR = 7.65; HR = 6.09; HR = 7.28). Smaller PSA nadir (≤ 1.0 µg/L) and longer TTPN (> 3 months) were associated with increased 5-year survival rate (P < 0.05). Conclusions: The combined efficacies of WB-MRI, bone scintigraphy and PSA levels were desired in identifying PCa lesions and prognosis.

scholarly journals MONOSTOTIC OSTEOFIBROUS DYSPLASIA OF THE TIBIA

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Maimoona Siddique ◽  
Humayun Bashir ◽  
Imran K Niazi ◽  
Ahsan Shamim
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Bone Scintigraphy ◽  
Single Photon ◽  
Photon Emission ◽  
Tracer Uptake ◽  
Whole Body ◽  
Emission Computed Tomography ◽  
Resonance Imaging

An 11-year-old boy presented with painful swelling of leg following fracture of tibia. Osteo brous dysplasia (OFD) is an uncommon, benign, non-hereditary bone disorder in which brous tissue develops in place of normal bone that affects the young adults in their rst and second decade of life. Tc-99m MDP whole-body bone scintigraphy revealed increased tracer uptake in dense proximal tibia. On single-photon remission computed tomography-computed tomography (SPECT-CT), radiological features of cortical-based lesion superimposed on abnormal tracer uptake con rmed it to be a monostotic OFD. This case emphasises the role of SPECT-CT and magnetic resonance imaging in detecting osteo brous dysplasia and differentiating it from other benign bone conditions. Key words: Bone scintigraphy, magnetic resonance imaging, monostotic osteo brous dysplasia, single-photon emission computed tomography computed tomography, tibia

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