Localization of pancreatic polypeptide cells in a limited lobe of the human neonate pancreas: Remnant of the ventral primordium?

1979 ◽  
Vol 200 (3) ◽  
Author(s):  
J. Rahier ◽  
J. Wallon ◽  
W. Gepts ◽  
J. Haot
1980 ◽  
Vol 69 (2) ◽  
pp. 211-214 ◽  
Author(s):  
A. LUCAS ◽  
T. E. ADRIAN ◽  
S. R. BLOOM ◽  
A. AYNSLEY-GREEN

1980 ◽  
Vol 65 (3) ◽  
pp. 261-267 ◽  
Author(s):  
Ann Andrew ◽  
B. B. Rawdon

Diabetologia ◽  
1977 ◽  
Vol 13 (1) ◽  
pp. 27-34 ◽  
Author(s):  
W. Gepts ◽  
J. De Mey ◽  
M. Marichal-Pipeleers

1979 ◽  
Vol 27 (9) ◽  
pp. 1281-1282 ◽  
Author(s):  
S Falkmer

By using both immunofluorescence and peroxidase-anti-peroxidase procedures to detect cells producing the four islet hormones, supplemented by biochemical, biological, and radioimmunological assays of tissue extracts, it has been shown that insulin seems to be the most original hormone, apparently occurring already in invertebrates in cells of open type in the alimentary tract mucosa. Insulin cells also predominate in the first islet organ, namely that of the cyclostomes. The order of appearance in the endocrine pancreas during the subsequent evolution is: somatostatin; glucagon; and the pancreatic polypeptide. Even in lower vertebrates pancreatic polypeptide cells occur in those parts of the pancreas situated in close proximity to the gut.


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