The NADPH oxidase of guinea pig polymorphonuclear leucocytes

1983 ◽  
Vol 52 (1) ◽  
Author(s):  
Paolo Bellavite ◽  
MariaC. Serra ◽  
Anna Davoli ◽  
JoeV. Bannister ◽  
Filippo Rossi
Keyword(s):  
Guinea Pig ◽  
Nadph Oxidase ◽  
Polymorphonuclear Leucocytes

NADPH AND NADH OXIDATION BY GUINEA PIG POLYMORPHONUCLEAR LEUCOCYTES

1963 ◽  
Vol 41 (2) ◽  
pp. 427-434 ◽  
Author(s):  
G. Y. N. Iyer ◽  
J. H. Quastel
Keyword(s):  
Hydrogen Peroxide ◽  
Guinea Pig ◽  
Nadph Oxidase ◽  
Oxidase Activity ◽  
Enzyme System ◽  
Polymorphonuclear Leucocytes ◽  
Hexose Monophosphate ◽  
Manganese Ions ◽  
Hexose Monophosphate Pathway ◽  
Stimulation Of

A homogenate of guinea pig polymorphonuclear leucocytes contains an enzyme system capable of oxidizing, in presence of oxygen, NADPH and NADH with the formation of hydrogen peroxide. The enzyme is much more active towards NADPH than to NADH. The presence of manganese ions strongly enhances the oxidase activity. It is suggested that the release of the NADPH oxidase in the leucocytes, during phagocytosis, accounts for the stimulation of the hexose monophosphate pathway that occurs in phagocytosis.

NADPH AND NADH OXIDATION BY GUINEA PIG POLYMORPHONUCLEAR LEUCOCYTES

1963 ◽  
Vol 41 (1) ◽  
pp. 427-434 ◽  
Author(s):  
G. Y. N. Iyer ◽  
J. H. Quastel
Keyword(s):  
Hydrogen Peroxide ◽  
Guinea Pig ◽  
Nadph Oxidase ◽  
Oxidase Activity ◽  
Enzyme System ◽  
Polymorphonuclear Leucocytes ◽  
Hexose Monophosphate ◽  
Manganese Ions ◽  
Hexose Monophosphate Pathway ◽  
Stimulation Of

A homogenate of guinea pig polymorphonuclear leucocytes contains an enzyme system capable of oxidizing, in presence of oxygen, NADPH and NADH with the formation of hydrogen peroxide. The enzyme is much more active towards NADPH than to NADH. The presence of manganese ions strongly enhances the oxidase activity. It is suggested that the release of the NADPH oxidase in the leucocytes, during phagocytosis, accounts for the stimulation of the hexose monophosphate pathway that occurs in phagocytosis.

Electrostatic interaction of microcapsules with guinea-pig polymorphonuclear leucocytes

1990 ◽  
Vol 7 (2) ◽  
pp. 179-184 ◽  
Author(s):  
Satoshi Yasukawa ◽  
Hiroyuki Ohshima ◽  
Nobuhiro Muramatsu ◽  
Tamotsu Kondo
Keyword(s):  
Guinea Pig ◽  
Electrostatic Interaction ◽  
Polymorphonuclear Leucocytes

scholarly journals Pharmacological comparison of LTB4 -induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils

2001 ◽  
Vol 134 (4) ◽  
pp. 797-806 ◽  
Author(s):  
Oonagh T Lynch ◽  
Mark A Giembycz ◽  
Peter J Barnes ◽  
Mark A Lindsay
Keyword(s):  
Guinea Pig ◽  
Nadph Oxidase ◽  
Nadph Oxidase Activation

Phagocytosis of microcapsules by guinea-pig polymorphonuclear leucocytes

1986 ◽  
Vol 3 (4) ◽  
pp. 265-273 ◽  
Author(s):  
Tatsuya Sano ◽  
Nobuhiro Muramatsu ◽  
Tamotsu Kondo
Keyword(s):  
Guinea Pig ◽  
Polymorphonuclear Leucocytes

Translocation of the 46 kDa Protein(s) in Response to Activation of NADPH Oxidase in Guinea Pig Polymorphonuclear Leukocytes1

1990 ◽  
Vol 108 (2) ◽  
pp. 169-174 ◽  
Author(s):  
Toshiaki Ohtsuka ◽  
Mayumi Nakamura ◽  
Masanori Hiura ◽  
Klyomi Yoshida ◽  
Naoki Okamura ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Nadph Oxidase ◽  
Protein S
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