Influence of the superior colliculus on visual responses of cells in the rabbit's lateral posterior nucleus

1990 ◽  
Vol 80 (2) ◽  
Author(s):  
C. Casanova ◽  
S. Molotchnikoff
Keyword(s):  
Superior Colliculus ◽  
Visual Responses ◽  
Lateral Posterior ◽  
Lateral Posterior Nucleus

Organization of projections from the superior colliculus to the thalamic lateral posterior nucleus in the rat

1983 ◽  
Vol 288 (1-2) ◽  
pp. 315-319 ◽  
Author(s):  
James F. Donnelly ◽  
Scott M. Thompson ◽  
Richard T. Robertson
Keyword(s):  
Superior Colliculus ◽  
Lateral Posterior ◽  
Lateral Posterior Nucleus

Glutamate containing neurons in the cat superior colliculus revealed by immunocytochemistry

1997 ◽  
Vol 14 (2) ◽  
pp. 387-393 ◽  
Author(s):  
Chang-Jin Jeon ◽  
Michael R. Gurski ◽  
R. Ranney Mize
Keyword(s):  
Electron Microscope ◽  
Superior Colliculus ◽  
Projection Neurons ◽  
Electron Microscope Level ◽  
Cortical Afferents ◽  
Lateral Posterior ◽  
Laminar Pattern ◽  
Lateral Posterior Nucleus ◽  
Dense Band ◽  
Cat Superior Colliculus

AbstractGlutamate is the probable neurotransmitter of both retinal and cortical afferents to the cat superior colliculus (SC). The present study shows that glutamate is also contained in many postsynaptic neurons in SC. The distribution, morphology, and ultrastructure of neurons in SC were examined using glutamate antibody immunocytochemistry. Labeled cells were widely distributed throughout, but a specific laminar pattern was evident. Relatively few cells were found in the zonal and upper superficial gray layers (SGL). A dense band of intensely labeled neurons was found within the deep superficial gray and upper optic layers. Many cells were also labeled in the deeper layers. Labeled cells had varied sizes and morphologies. Soma diameters ranged from 9–67 μm, with a mean of 22 μm. Cells with stellate, vertical fusiform, and multipolar morphologies were labeled. Cells in the deep subdivision all had morphologies and sizes typical of projection neurons. To determine if labeled cells in the dense band were also projection neurons, WGA-HRP was injected into the lateral posterior nucleus and these sections were double-labeled with the glutamate antibody. Over one-half of cells in the dense band that were labeled by HRP were also obviously labeled by antibody. At the electron-microscope level, both medium- and large-sized neurons were also labeled by glutamate antibodies. These cells had different but characteristic morphologies.

Anatomical and functional organization of pathway from superior colliculus to lateral posterior nucleus in hamster

1984 ◽  
Vol 51 (3) ◽  
pp. 407-431 ◽  
Author(s):  
R. D. Mooney ◽  
S. E. Fish ◽  
R. W. Rhoades
Keyword(s):  
Receptive Field ◽  
Superior Colliculus ◽  
Functional Organization ◽  
Single Cells ◽  
Angular Separation ◽  
Unit Recording ◽  
Receptive Field Properties ◽  
Lateral Posterior ◽  
Lateral Posterior Nucleus ◽  
Lp Cells

A series of anatomical (autoradiographic and horseradish peroxidase, HRP) and electrophysiological experiments were carried out to determine the organization of the pathway from the superior colliculus (SC) to the lateral posterior nucleus (LP) in the hamster. Small, electrophoretic HRP deposits restricted to LP labeled numerous cells in both the ipsilateral and contralateral colliculus. Over 95% of the labeled cells were located in the lower one-half of the stratum griseum superficiale (SGS) and the upper stratum opticum (SO). A number of different morphological cell types contributed axons to the tecto-LP pathway. The receptive-field properties of antidromically activated tecto-LP neurons were delineated using extracellular single-unit recording techniques. Ninety-eight percent of the tecto-LP cells recorded were isolated in the SGS and SO. All tecto-LP cells responded more vigorously to moving than to flashed stimuli, one-third were directionally selective, and one-third exhibited some degree of speed selectivity. The responses of tecto-LP neurons did not differ appreciably from those of superficial layer collicular cells that could not be antidromically activated by LP shocks. Small pressure injections or electrophoretic deposits of [3H]leucine into sites with known retinotopy in the superficial collicular laminae were used to determine whether or not the tecto-LP projection in hamster was topographically organized. Injections anywhere in the SGS and SO yielded dense label in almost all of the caudal (LPc) and rostrolateral (LPrl) subnuclei of LP, ipsilaterally, and sparser labeling in these same subnuclei, contralaterally. No injection produced significant labeling in the rostromedial (LPrm) subnucleus. Our autoradiographic data gave no indication of any topographic order in the tecto-LP projection. Electrophysiological methods were also used to map the tecto-LP projection. Multiple stimulating microelectrodes were positioned at physiologically defined sites in the SGS, and single cells were recorded in LP, ipsilaterally. Threshold currents for activation of LP cells from different collicular sites were then compared with the angular separation of SC and LP receptive-field centers. No significant correlation between these two variables was noted, again indicating a lack of topographic organization in the tecto-LP projection. The receptive-field properties of individual LP neurons (n = 211) were also assessed and correlated with subnuclear location and responsivity to SC shocks.(ABSTRACT TRUNCATED AT 400 WORDS)

Projection status of calbindin- and parvalbumin-immunoreactive neurons in the superficial layers of the rat's superior colliculus

1997 ◽  
Vol 14 (2) ◽  
pp. 277-286 ◽  
Author(s):  
Richard D. Lane ◽  
Dawn M. Allan ◽  
Carol A. Bennett-Clarke ◽  
David L. Howell ◽  
Robert W. Rhoades
Keyword(s):  
Superior Colliculus ◽  
Calcium Binding ◽  
Neuronal Population ◽  
Dorsal Lateral Geniculate Nucleus ◽  
Projection Neurons ◽  
Retrograde Labeling ◽  
Thalamic Projections ◽  
Lateral Posterior ◽  
Lateral Posterior Nucleus ◽  
Dorsal Lateral Geniculate

AbstractImmunocytochemistry and retrograde labeling were used to define the thalamic projections of calbindin- and parvalbumin-containing cells in superficial layers of the rat's superior colliculus (SC). Quantitative analysis revealed that 90.8 ± 2.2% (mean ± standard deviation) of the calbindin-immunoreactive neurons in the stratum griseum superficiale (SGS) projected to the dorsal lateral geniculate nucleus (LGNd) and that 91.3 ± 4.3% of calbindin-immunoreactive neurons in the stratum opticum (SO) projected to the lateral posterior nucleus (LP). In contrast, only 17.3 ± 2.5% of parvalbumin-immunoreactive neurons in the SGS were found to project to the LGNd and 16.5 ± 3.1% of the parvalbumin-immunoreactive SO cells were retrogradely labeled after LP injections. Few of the parvalbumin-immunoreactive neurons in either the SGS (7.2 ± 2.5%) or the SO (9.2 ± 2.5%) were GABA positive. The retrograde-labeling results suggest that parvalbumin-immunoreactive neurons in the rat's SO and SGS may either be primarily interneurons or have descending projections, while calbindin-containing cells are primarily thalamic projection neurons. These results are consistent with data from other rodents, but almost exactly the opposite of data that have been reported for the cat for these same populations of SC projection neurons. Such interspecies differences raise questions regarding the functional importance of expressing one calcium-binding protein versus another in a specific neuronal population.

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