Ear and eye representation in the frontal cortex, area 8b, of the macaque monkey: an electrophysiological study

1994 ◽  
Vol 102 (2) ◽  
Author(s):  
L. Bon ◽  
C. Lucchetti
Keyword(s):  
Frontal Cortex ◽  
Electrophysiological Study ◽  
Macaque Monkey ◽  
Cortex Area

scholarly journals Combined Transcriptomics and Proteomics in Frontal Cortex Area 8 in Frontotemporal Lobar Degeneration Linked to C9ORF72 Expansion

2019 ◽  
Vol 68 (3) ◽  
pp. 1287-1307 ◽  
Author(s):  
Pol Andrés-Benito ◽  
Ellen Gelpi ◽  
Mónica Povedano ◽  
Karina Ausín ◽  
Joaquín Fernández-Irigoyen ◽  
...  
Keyword(s):  
Frontal Cortex ◽  
Frontotemporal Lobar Degeneration ◽  
C9orf72 Expansion ◽  
Cortex Area

Spatial tuning of reaching activity in the medial parieto-occipital cortex (area V6A) of macaque monkey

2005 ◽  
Vol 22 (4) ◽  
pp. 956-972 ◽  
Author(s):  
Patrizia Fattori ◽  
Dieter F. Kutz ◽  
Rossella Breveglieri ◽  
Nicoletta Marzocchi ◽  
Claudio Galletti
Keyword(s):  
Occipital Cortex ◽  
Macaque Monkey ◽  
Spatial Tuning ◽  
Cortex Area

scholarly journals TDP-43 Vasculopathy in the Spinal Cord in Sporadic Amyotrophic Lateral Sclerosis (sALS) and Frontal Cortex in sALS/FTLD-TDP

2021 ◽  
Vol 80 (3) ◽  
pp. 229-239
Author(s):  
Isidro Ferrer ◽  
Pol Andrés-Benito ◽  
Margarita Carmona ◽  
Abdelilah Assialioui ◽  
Mónica Povedano
Keyword(s):  
Spinal Cord ◽  
Amyotrophic Lateral Sclerosis ◽  
Frontal Cortex ◽  
Blood Vessels ◽  
External Surface ◽  
Sporadic Amyotrophic Lateral Sclerosis ◽  
Double Labeling ◽  
Cortex Area ◽  
Altered Blood ◽  
Lateral Sclerosis

Abstract Sporadic amyotrophic lateral sclerosis (sALS) and FTLD-TDP are neurodegenerative diseases within the spectrum of TDP-43 proteinopathies. Since abnormal blood vessels and altered blood-brain barrier have been described in sALS, we wanted to know whether TDP-43 pathology also occurs in blood vessels in sALS/FTLD-TDP. TDP-43 deposits were identified in association with small blood vessels of the spinal cord in 7 of 14 cases of sALS and in small blood vessels of frontal cortex area 8 in 6 of 11 FTLD-TDP and sALS cases, one of them carrying a GRN mutation. This was achieved using single and double-labeling immunohistochemistry, and double-labeling immunofluorescence and confocal microscopy. In the sALS spinal cord, P-TDP43 Ser403-404 deposits were elongated and parallel to the lumen, whereas others were granular, seldom forming clusters. In the frontal cortex, the inclusions were granular, or elongated and parallel to the lumen, or forming small globules within or in the external surface of the blood vessel wall. Other deposits were localized in the perivascular space. The present findings are in line with previous observations of TDP-43 vasculopathy in a subset of FTLD-TDP cases and identify this pathology in the spinal cord and frontal cortex in a subset of cases within the sALS/FTLD-TDP spectrum.

Immunohistochemical analysis for catecholamine innervation of the frontal cortex in macaque monkey

1989 ◽  
Vol 9 ◽  
pp. 142
Author(s):  
Hiroko Matsumura ◽  
Masaya Fujii ◽  
Shuji Iritani ◽  
Keiji Satoh ◽  
Ikuko Nagatsu
Keyword(s):  
Frontal Cortex ◽  
Immunohistochemical Analysis ◽  
Macaque Monkey

scholarly journals Complex Inflammation mRNA-Related Response in ALS Is Region Dependent

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Sara Berjaoui ◽  
Mónica Povedano ◽  
Paula Garcia-Esparcia ◽  
Margarita Carmona ◽  
Ester Aso ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Frontal Cortex ◽  
Motor Neurons ◽  
Unknown Origin ◽  
Lumbar Spinal Cord ◽  
Pyramidal Tracts ◽  
Abnormal Distribution ◽  
Cortex Area ◽  
Lumbar Spinal ◽  
Inflammatory Changes

Inflammatory changes are analyzed in the anterior spinal cord and frontal cortex area 8 in typical spinal-predominant ALS cases. Increased numbers of astrocytes and activated microglia are found in the anterior horn of the spinal cord and pyramidal tracts. Significant increased expression ofTLR7,CTSS, andCTSCmRNA and a trend to increased expression ofIL10RA,TGFB1, andTGFB2are found in the anterior lumbar spinal cord in ALS cases compared to control cases, whereasC1QTNF7andTNFRSF1AmRNA expression levels are significantly decreased.IL6is significantly upregulated andIL1Bshows a nonsignificant increased expression in frontal cortex area 8 in ALS cases. IL-6 immunoreactivity is found in scattered monocyte-derived macrophages/microglia and TNF-αin a few cells of unknown origin in ALS cases. Increased expression and abnormal distribution of IL-1βoccurred in motor neurons of the lumbar spinal cord in ALS. Strong IL-10 immunoreactivity colocalizes with TDP-43-positive inclusions in motor neurons in ALS cases. The present observations show a complex participation of cytokines and mediators of the inflammatory response in ALS consistent with increased proinflammatory cytokines and sequestration of anti-inflammatory IL-10 in affected neurons.

scholarly journals Mitochondrial activity in the frontal cortex area 8 and angular gyrus in Parkinson's disease and Parkinson's disease with dementia

2017 ◽  
Vol 28 (1) ◽  
pp. 43-57 ◽  
Author(s):  
Paula Garcia-Esparcia ◽  
Anusha Koneti ◽  
M. Cruz Rodríguez-Oroz ◽  
Belen Gago ◽  
José Antonio del Rio ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Frontal Cortex ◽  
Angular Gyrus ◽  
Mitochondrial Activity ◽  
Cortex Area ◽  
Parkinson’S Disease With Dementia

scholarly journals Bayesian Correction for Attenuation of Correlation in Multi-Trial Spike Count Data

2009 ◽  
Vol 101 (4) ◽  
pp. 2186-2193 ◽  
Author(s):  
Sam Behseta ◽  
Tamara Berdyyeva ◽  
Carl R. Olson ◽  
Robert E. Kass
Keyword(s):  
Frontal Cortex ◽  
Recent Work ◽  
Confidence Intervals ◽  
Simulation Study ◽  
Count Data ◽  
Single Neuron ◽  
Serial Order ◽  
Macaque Monkey ◽  
Single Neuron Recording ◽  
Correction For Attenuation

When correlation is measured in the presence of noise, its value is decreased. In single-neuron recording experiments, for example, the correlation of selectivity indices in a pair of tasks may be assessed across neurons, but, because the number of trials is limited, the measured index values for each neuron will be noisy. This attenuates the correlation. A correction for such attenuation was proposed by Spearman more than 100 yr ago, and more recent work has shown how confidence intervals may be constructed to supplement the correction. In this paper, we propose an alternative Bayesian correction. A simulation study shows that this approach can be far superior to Spearman's, both in accuracy of the correction and in coverage of the resulting confidence intervals. We demonstrate the usefulness of this technology by applying it to a set of data obtained from the frontal cortex of a macaque monkey while performing serial order and variable reward saccade tasks. There the correction results in a substantial increase in the correlation across neurons in the two tasks.

scholarly journals Proactive and Reactive Processes in the Medial Frontal Cortex: An Electrophysiological Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e84351 ◽  
Author(s):  
Flavio T. P. Oliveira ◽  
Clayton Hickey ◽  
John J. McDonald
Keyword(s):  
Frontal Cortex ◽  
Electrophysiological Study ◽  
Medial Frontal Cortex ◽  
Reactive Processes
Sign in / Sign up

Export Citation Format

Share Document