Glial cells positive for glial fibrillary acidic protein in the neurohypophysis of the Djungarian hamster (Phodopus sungorus)

1987 ◽  
Vol 249 (2) ◽  
Author(s):  
P. Redecker ◽  
W. Wittkowski ◽  
K. Hoffmann
Keyword(s):  
Glial Fibrillary Acidic Protein ◽  
Glial Cells ◽  
Acidic Protein ◽  
Phodopus Sungorus ◽  
Djungarian Hamster

Coexpression of vimentin and glial fibrillary acidic protein in glial cells of the adult rat pineal gland

1992 ◽  
Vol 12 (4) ◽  
pp. 145-148 ◽  
Author(s):  
Francisco López-Munoz ◽  
Jose Luis Calvo ◽  
Jesus Boya ◽  
Angel L. Carboneil
Keyword(s):  
Glial Fibrillary Acidic Protein ◽  
Pineal Gland ◽  
Glial Cells ◽  
Acidic Protein ◽  
Adult Rat ◽  
Rat Pineal Gland

scholarly journals Aberrant Development of Enteric Glial Cells in the Colon of Hirschsprung's Disease

2021 ◽  
Vol 9 ◽  
Author(s):  
Tingting Zhou ◽  
Wei Liu ◽  
Xiaofang Yu ◽  
Zengcai Cao ◽  
Weijing Mu ◽  
...  
Keyword(s):  
Glial Fibrillary Acidic Protein ◽  
Glial Cells ◽  
Calcium Binding ◽  
Hirschsprung's Disease ◽  
Binding Protein ◽  
Calcium Binding Protein ◽  
Acidic Protein ◽  
S100 Calcium Binding Protein ◽  
Enteric Glial Cells ◽  
Protein B

Objective: The aim of this study was to explore the development of enteric glial cells (EGCs) in different segments of Hirschsprung's disease (HSCR).Methods: Colonic specimens from 35 children with HSCR were selected to analyze the relative expression of glial fibrillary acidic protein and S100 calcium-binding protein B using Western blotting and real-time fluorescence quantitative PCR. Immunofluorescence and immunohistochemical staining were performed to determine the distribution of myenteric EGCs and neuronal cells in different segments of HSCR.Results: There was a trend of diminished protein and mRNA expression of glial fibrillary acidic protein and S100 calcium-binding protein B from the proximal, dilated, and transitional segments to the aganglionic segment (p < 0.05). Immunofluorescence and immunohistochemistry showed that the EGCs in the aganglionic, transitional, and dilated colonic muscles were morphologically abnormal, which was consistent with the dysplasia of myenteric neurons.Conclusion: Aberrant development of myenteric EGCs was observed in the colon of HSCR, which may affect the survival of enteric neurons.

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