The efferent connections of the nucleus accumbens in the lizard Gekko gecko

1995 ◽  
Vol 191 (1) ◽  
Author(s):  
WilhelmusJ.A.J. Smeets ◽  
Loreta Medina
2013 ◽  
Vol 11 (3) ◽  
pp. 3-19
Author(s):  
Mariya Vladimirovna Sheveleva ◽  
Andrey Andreyevich Lebedev ◽  
Roman Olegovich Roik ◽  
Petr Dmitriyevich Shabanov

The review devoted to neurobiological mechanisms of both positive and negative reinforcement is represented. The key role in these processes plays the nucleus accumbens as a part of the extended amygdala system. The afferent and efferent connections of the n.accumbens, starting mechanisms of the n.accumbens involvement in emotional reactions, interactions between n.accumbens and other structures of the extended amygdala system, and neurochemical organization of the n.accumbens and all system of reinforcement are discussed in the article. The special attention is taken to the n.accumbens participation in addictive behavior.


2021 ◽  
Vol 15 ◽  
Author(s):  
Amanda G. Iglesias ◽  
Shelly B. Flagel

In this review, we highlight evidence that supports a role for the paraventricular nucleus of the thalamus (PVT) in motivated behavior. We include a neuroanatomical and neurochemical overview, outlining what is known of the cellular makeup of the region and its most prominent afferent and efferent connections. We discuss how these connections and distinctions across the anterior-posterior axis correspond to the perceived function of the PVT. We then focus on the hypothalamic-thalamic-striatal circuit and the neuroanatomical and functional placement of the PVT within this circuit. In this regard, the PVT is ideally positioned to integrate information regarding internal states and the external environment and translate it into motivated actions. Based on data that has emerged in recent years, including that from our laboratory, we posit that orexinergic (OX) innervation from the lateral hypothalamus (LH) to the PVT encodes the incentive motivational value of reward cues and thereby alters the signaling of the glutamatergic neurons projecting from the PVT to the shell of the nucleus accumbens (NAcSh). The PVT-NAcSh pathway then modulates dopamine activity and resultant cue-motivated behaviors. As we and others apply novel tools and approaches to studying the PVT we will continue to refine the anatomical, cellular, and functional definitions currently ascribed to this nucleus and further elucidate its role in motivated behaviors.


Neuroscience ◽  
1978 ◽  
Vol 3 (4-5) ◽  
pp. 385-401 ◽  
Author(s):  
W.J.H. Nauta ◽  
G.P. Smith ◽  
R.L.M. Faull ◽  
Valerie B. Domesick

Neuroanatomy ◽  
1993 ◽  
pp. 432-448
Author(s):  
W. J. H. Nauta ◽  
G. P. Smith ◽  
R. L. M. Faull ◽  
Valerie B. Domesick

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