In vitro effects of histamine liberator compound 48/80 on rat superior cervical ganglia with special regard to the small granule-containing cells

1976 ◽  
Vol 166 (1) ◽  
pp. 71-81 ◽  
Author(s):  
H. Behrendt ◽  
T. Lindl ◽  
H. Cramer
Keyword(s):  
Small Granule ◽  
Superior Cervical Ganglia ◽  
Special Regard ◽  
Cervical Ganglia ◽  
In Vitro Effects ◽  
Histamine Liberator

Temporal analysis of the anti-inflammatory effects of decentralization of the rat superior cervical ganglia

1994 ◽  
Vol 266 (5) ◽  
pp. R1537-R1543 ◽  
Author(s):  
R. Mathison ◽  
L. Carter ◽  
C. Mowat ◽  
E. Bissonnette ◽  
J. S. Davison ◽  
...  
Keyword(s):  
Pulmonary Inflammation ◽  
Allergen Challenge ◽  
Temporal Analysis ◽  
Lavage Fluid ◽  
Tnf Alpha ◽  
Nippostrongylus Brasiliensis ◽  
Superior Cervical Ganglia ◽  
Necrosis Factor Alpha ◽  
Cervical Ganglia

Bilateral decentralization of the superior cervical ganglia (SCG) reduced the pulmonary inflammation that develops 4-8 h after induction of anaphylaxis in Nippostrongylus brasiliensis-sensitized rats. Histamine levels in peritoneal lavage fluid and rat mast cell protease type II in serum were increased to comparable levels in sham-operated and decentralized rats. In vitro stimulation of alveolar macrophages (ALM) with lipopolysaccharide (LPS) provoked tumor necrosis factor-alpha (TNF-alpha) release that was two to three times greater with unchallenged decentralized rats than with sham-operated rats. However, after allergen challenge LPS-stimulated TNF-alpha release from ALM of sham-operated rats increased threefold and lasted at least 24 h, whereas with decentralized rats release of this cytokine actually decreased at 4 and 8 h. The increase in the phagocytosis and respiratory burst of circulating neutrophils seen at 4 and 8 h after allergen challenge in sham-operated rats was reduced significantly by decentralization. These results suggest that the attenuation of anaphylaxis-induced pulmonary inflammation that occurs with decentralization of the SCG is primarily associated with downregulation of neutrophil and macrophage functions.

Stimulation-induced release of norepinephrine from rat superior cervical ganglia in vitro

1972 ◽  
Vol 20 (3) ◽  
pp. 308-311 ◽  
Author(s):  
Steven A. Vogel ◽  
Stephen D. Silberstein ◽  
Kenneth R. Berv ◽  
Irwin J. Kopin
Keyword(s):  
Superior Cervical Ganglia ◽  
Cervical Ganglia
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