Neuropeptide Y-, substance P- and VIP-immunoreactive nerves in cat spleen in relation to autonomic vascular and volume control

1985 ◽  
Vol 239 (1) ◽  
pp. 9-18 ◽  
Author(s):  
J. M. Lundberg ◽  
A. Änggård ◽  
J. Pernow ◽  
T. Hökfelt
Keyword(s):  
Substance P ◽  
Neuropeptide Y ◽  
Volume Control ◽  
Cat Spleen

Substance P and neuropeptide Y inhibit progesterone release from porcine granulosa and luteal cells

1989 ◽  
Vol 120 (3_Suppl) ◽  
pp. S178
Author(s):  
W. WUTTKE ◽  
B. HALLMANN ◽  
L. PITZEL
Keyword(s):  
Substance P ◽  
Neuropeptide Y ◽  
Luteal Cells

scholarly journals Vasomotor Responses of Rat Intracerebral Arterioles to Vasoactive Intestinal Peptide, Substance P, Neuropeptide Y, and Bradykinin

1988 ◽  
Vol 8 (2) ◽  
pp. 254-261 ◽  
Author(s):  
Ralph G. Dacey ◽  
John E. Bassett ◽  
Masakazu Takayasu
Keyword(s):  
Smooth Muscle ◽  
Substance P ◽  
Neuropeptide Y ◽  
Vasoactive Intestinal Peptide ◽  
Vessel Diameter ◽  
Cerebral Microcirculation ◽  
Vasoactive Peptides ◽  
Spontaneous Tone ◽  
Ph Dependent ◽  
Dose Dependent

The effect of vasoactive peptides on vascular smooth muscle in the cerebral microcirculation was examined using an isolated intracerebral arteriole preparation. Extraluminally applied vasoactive intestinal peptide (VIP) dilated the spontaneous tone of intracerebral arterioles to 118.9 ± 3.1% of control diameter at pH 7.30, with an EC50 of 7.27 × 10−8 M. Similar degrees of dilation to VIP were seen in vessels preconstricted by changing bath solution to pH 7.60. Substance P had no effect on vessel diameter at pH 7.30. However, in vessels precontracted by pH 7.60, significant dose-dependent dilation was observed with an EC50 of 2.55 × 10−10 M. Neuropeptide constricted intracerebral arterioles to 8l.22 ± 2.7% of control diameter, with an EC50 of 6.23 × 10−10 M. Bradykinin dilated intracerebral arterioles at pH 7.30 and pH 7.60 to 130 ± 3.0% of control diameter. VIP and bradykinin are potent vasodilators of intracerebral arterioles. Neuropeptide Y is a vasoconstrictor. The effect of substance P appeared to be either pH-dependent or dependent on some degree of precontraction by another agonist, but no effect on vessel diameter was seen at pH 7.30.

scholarly journals Immunohistochemical evidence for the presence of a vasoactive intestinal peptide, neuropeptide Y and substance P in rat adrenal medulla after heat stress

2012 ◽  
Vol 64 (1) ◽  
pp. 7-13
Author(s):  
Dragana Petrovic-Kosanovic ◽  
Vesna Koko
Keyword(s):  
Heat Stress ◽  
Substance P ◽  
Neuropeptide Y ◽  
Vasoactive Intestinal Peptide ◽  
Adrenal Medulla ◽  
Chromaffin Cells ◽  
Ganglion Cells ◽  
Nerve Fibers ◽  
Acute Heat Stress ◽  
Immunohistochemical Evidence

Immunohistochemistry revealed the presence of VIP-, NPY- and SP-immunoreactivity in the rat adrenal medulla. VIP- and NPY-immunoreactivity was detected in chromaffin and ganglion cells and in nerve fibers, but SP-immunoreactivity was found only in chromaffin cells. After acute heat stress, VIP- and NPY- immunoreactivities in cells and nerve fibers were reduced, probably as a result of the release of these peptides with catecholamines. The absence of SP-immunoreactive ganglion cells in the adrenal medulla suggests that the SP-immunoreactive nerve fibers are extrinsic in origin.

Decreased levels of [Met]enkephalin, neuropeptide Y, substance P, and vasoactive intestinal peptide in parkinsonian adrenal medulla

1991 ◽  
Vol 114 (1) ◽  
pp. 23-27 ◽  
Author(s):  
Susan L. Stoddard ◽  
Gertrude M. Tyce ◽  
J.Eric Ahlskog ◽  
Alan R. Zinsmeister ◽  
Daniel K. Nelson ◽  
...  
Keyword(s):  
Substance P ◽  
Neuropeptide Y ◽  
Vasoactive Intestinal Peptide ◽  
Adrenal Medulla
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