Mono-ortho- and non-ortho-substituted polychlorinated biphenyls in human milk from Mohawk and control women: Effects of maternal factors and previous lactation

Author(s):  
C.S. Hong ◽  
J. Xiao ◽  
A.C. Casey ◽  
B. Bush ◽  
E.F. Fitzgerald ◽  
...  
1986 ◽  
Vol 76 (2) ◽  
pp. 172-177 ◽  
Author(s):  
W J Rogan ◽  
B C Gladen ◽  
J D McKinney ◽  
N Carreras ◽  
P Hardy ◽  
...  

BMC Nutrition ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Christine Chimanuka Murhima’Alika ◽  
Ghislain Maheshe Balemba ◽  
Pacifique Mwene-Batu Lyabayungu ◽  
Guy Mulinganya Mulume’oderhwa ◽  
Grace Munthali ◽  
...  

Abstract Background Malnutrition is a public health problem, as wasting affects 7.5% of children worldwide. The harmful effects of severe acute malnutrition (SAM) can last a lifetime, but how SAM in childhood affects later breastfeeding ability is not clear. In the present study, we assessed the human milk output and body composition among mothers with a history of childhood SAM. Methods This retrospective cohort study was carried out in Miti-Murhesa Health Zone (Democratic Republic of Congo) from January 15 to March 17, 2020. We selected lactating mothers with breastfed infants aged 2–12 months. Two categories of mothers were included: those who had been treated for SAM during their childhood (years 1988–2003; n = 39) and a community control with no history of SAM (n = 40). The weight, height, and mid-upper arm circumference were measured and body mass index (BMI) calculated as weight/height2. Body composition and human milk output were assessed using standard deuterium dilution methods. Student t and chi2 tests ware applied to compare two groups. Results The mean age ± standard deviation of the mothers was 24.4 ± 5.1 and 26.0 ± 6.1 years for the SAM and control groups, respectively (p = 0.186). The age of their infants was 5.4 ± 2.3 months in both groups (p = 0.962). In the SAM and control groups, the mean maternal BMI was 23.8 ± 2.3 and 23.6 ± 3.7 kg/m2 (p = 0.849), mean Fat Mass 27.1% ± 5.0 and 27.1% ± 5.8% (p = 0.708), and the mean Fat Free mass 72.9% ± 5.0 and 72.9% ± 5.8% (p = 0.998), respectively. Human milk output was 833.7 ± 152.1 g/d in SAM group and 827.4 ± 171.4 g/d in the control group (p = 0.864). Conclusions We found no significant difference in human milk output and body composition in mothers treated for SAM during childhood compared to community controls.


Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 152 ◽  
Author(s):  
Laura Galante ◽  
Hanna Lagström ◽  
Mark H. Vickers ◽  
Clare M. Reynolds ◽  
Samuli Rautava ◽  
...  

While human milk composition is characterised by marked dynamicity, we are far from having a clear picture of what factors drive this variation. Hormones in human milk are known to vary according to specific maternal phenotypes, but limited evidence shows the infant also has a role in determining milk composition. The present study aimed to investigate the interplay between maternal and infant characteristics in relation to human milk hormonal profile. In total, 501 human milk samples from mothers recruited in the Finnish STEPS cohort study (Steps to the healthy development) were analysed. Pre-pregnancy and pregnancy maternal data, socioeconomic status and infant characteristics at birth were collated. Leptin, adiponectin, insulin-like growth factor-1 and cyclic Glycine-Proline in milk were measured. Multivariate analysis of variance (MANOVA) and linear regression were utilised for statistical analysis. Sex-specific interactions with maternal factors were observed, as the infant sex mediated associations between gestational diabetes and milk adiponectin (p = 0.031), birth-mode and total protein (p = 0.003), maternal education and insulin-like growth factor-1: cyclic Glycine-Proline ratio (p = 0.035). Our results suggest that changes in human milk composition are associated with interactions between maternal and infant characteristics and pathophysiological factors. Future work should expand on these findings and further explore the link between hormonal profiles in human milk and infant outcomes.


1985 ◽  
Vol 48 (5) ◽  
pp. 442-448 ◽  
Author(s):  
BRIJ L. SAWHNEY ◽  
LESTER HANKIN

Literature published from 1970 through mid-1984 on polychlorinated biphenyl (PCB) contamination of foods, including fish, dairy products, packaged and processed food and human milk, is reviewed. Sources of the contamination are discussed. The reports show that although PCBs are no longer manufactured in this country, large quantities have entered the environment. High concentrations in sediments of some streams and lakes are a continuing source of PCB entry into the food chain via the fish caught in these waters. Accidental leakage and spills from electrical transformers containing PCBs, which are in use, can also be a source of contamination. Other sources of PCB contamination such as silo sealants and packaging materials manufactured from carbonless paper containing PCBs have been essentially eliminated.


Chemosphere ◽  
2017 ◽  
Vol 189 ◽  
pp. 32-38 ◽  
Author(s):  
Lei Zhang ◽  
Shuaixing Yin ◽  
Yunfeng Zhao ◽  
Zhixiong Shi ◽  
Jingguang Li ◽  
...  

2017 ◽  
Vol 280 ◽  
pp. S293
Author(s):  
Irena Brčić Karačonji ◽  
Andreja Jurič ◽  
Nataša Brajenović ◽  
Darija Klinčić ◽  
Snježana Herceg Romanić ◽  
...  

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