Use of microcosm and fish toxicity data to select mesocosm treatment concentrations

Author(s):  
F.S. Stay ◽  
A.W. Jarvinen
Keyword(s):  
2020 ◽  
Vol 16 (4) ◽  
pp. 452-460 ◽  
Author(s):  
Adam Lillicrap ◽  
S Jannicke Moe ◽  
Raoul Wolf ◽  
Kristin A Connors ◽  
Jane M Rawlings ◽  
...  

2019 ◽  
Author(s):  
S. Jannicke Moe ◽  
Anders L. Madsen ◽  
Kristin A. Connors ◽  
Jane M. Rawlings ◽  
Scott E. Belanger ◽  
...  

AbstractA Bayesian network was developed for predicting the acute toxicity intervals of chemical substances to fish, based on information on fish embryo toxicity (FET) in combination with other information. This model can support the use of FET data in a Weight-of-Evidence (WOE) approach for replacing the use of juvenile fish. The BN predicted correct toxicity intervals for 69%-80% of the tested substances. The model was most sensitive to components quantified by toxicity data, and least sensitive to components quantified by expert knowledge. The model is publicly available through a web interface. Further development of this model should include additional lines of evidence, refinement of the discretisation, and training with a larger dataset for weighting of the lines of evidence. A refined version of this model can be a useful tool for predicting acute fish toxicity, and a contribution to more quantitative WOE approaches for ecotoxicology and environmental assessment more generally.HighlightsA Bayesian network (BN) was developed to predict the toxicity of chemicals to fishThe BN uses fish embryo toxicity data in a quantitative weight-of-evidence approachThe BN integrates physical, chemical and toxicological properties of chemicalsCorrect toxicity intervals were predicted for 69-80% of test casesThe BN is publicly available for demonstration and testing through a web interface


2018 ◽  
Vol 28 (3) ◽  
pp. 605-611 ◽  
Author(s):  
Andrew Hylton ◽  
Ylenia Chiari ◽  
Isabella Capellini ◽  
Mace G. Barron ◽  
Scott Glaberman

1982 ◽  
Vol 14 (12) ◽  
pp. 5-14 ◽  
Author(s):  
D Mackay

The origins of “micropollutants” are discussed and classified. It is suggested that assessing the risk and ensuring an acceptably low level of adverse effects from these substances requires information or control of three factors (exposure, toxicity and characteristics of the victim or organism) which combine to generate the toxic event. Methods of estimating exposure are discussed, especially environmental models. Ultimately, it should be possible to couple these models to toxicity data in a rational, rigorous manner to elucidate the extent of risk and control it to acceptable levels.


1985 ◽  
Vol 17 (6-7) ◽  
pp. 1187-1198 ◽  
Author(s):  
G. Mance ◽  
A. R. O'Donnell

This paper discusses the derivation of environmental quality standards for coastal waters and the difficulties of using such standards for controlling industrial discharges. Attention is focused on the common List II substances, copper, chromium, lead, nickel, zinc and arsenic - and their effects on marine life. The adequacy of existing toxicity data is discussed and it is concluded that long exposure tests are required to provide information on sublethal effects. Such data are currently limited. It is also important that consideration be given to the effects that reducing salinities and increasing temperatures have in increasing the toxicity of these substances. The complexity of interpreting the results of laboratory toxicity data to coastal waters is discussed with reference to a study of the impact of an industrial discharge.


1992 ◽  
Vol 26 (9-11) ◽  
pp. 2345-2348 ◽  
Author(s):  
C. N. Haas

A new method for the quantitative analysis of multiple toxicity data is described and illustrated using a data set on metal exposure to copepods. Positive interactions are observed for Ni-Pb and Pb-Cr, with weak negative interactions observed for Ni-Cr.


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