Comparative analysis of the frequency of house dust mite specific and nonspecific Th1 and Th2 cells in skin lesions and peripheral blood of patients with atopic dermatitis

1996 ◽  
Vol 74 (7) ◽  
pp. 401-406 ◽  
Author(s):  
C. Neumann ◽  
C. Gutgesell ◽  
F. Fliegert ◽  
R. Bonifer ◽  
F. Herrmann
Keyword(s):  
Atopic Dermatitis ◽  
Comparative Analysis ◽  
House Dust ◽  
House Dust Mite ◽  
Peripheral Blood ◽  
Skin Lesions ◽  
Th2 Cells ◽  
Dust Mite ◽  
Th1 And Th2

The Hot-Water Extract of Smilacis Chinae Rhizome Suppresses 2,4-Dinitrochlorobenzene and House Dust Mite-Induced Atopic Dermatitis-Like Skin Lesions in Mice

2016 ◽  
Vol 30 (4) ◽  
pp. 636-645 ◽  
Author(s):  
Nam Yong Ki ◽  
Eun-Ji Park ◽  
In sung Sung ◽  
Seul A Ju ◽  
Kyoung Un Kim ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
House Dust ◽  
House Dust Mite ◽  
Water Extract ◽  
Skin Lesions ◽  
Hot Water ◽  
Hot Water Extract ◽  
Dust Mite

scholarly journals Immunohistopathological Analysis of Immunoglobulin E-Positive Epidermal Dendritic Cells with House Dust Mite Antigens in Naturally Occurring Skin Lesions of Adult and Elderly Patients with Atopic Dermatitis

2021 ◽  
Vol 8 (3) ◽  
pp. 426-441
Author(s):  
Ryoji Tanei ◽  
Yasuko Hasegawa
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Atopic Dermatitis ◽  
House Dust ◽  
House Dust Mite ◽  
Immunoglobulin E ◽  
Skin Lesions ◽  
Delayed Type Hypersensitivity ◽  
Dust Mite ◽  
Epidermal Dendritic Cells

The immunopathogenic role of house dust mite (HDM) allergens in the development of skin lesions in atopic dermatitis (AD) has not yet been precisely clarified. We immunohistopathologically evaluated the localization of immunoglobulin E (IgE)-positive epidermal dendritic cells with HDM antigens in the skin lesions of patients with IgE-allergic AD. Using double-immunofluorescence and single-immunochemical staining methods, we analyzed biopsy specimens from the skin lesions of six patients with IgE-allergic AD and HDM allergy and 11 control subjects with inflammatory skin disorders. Inflammatory dendritic epidermal cells (IDECs; CD11c+ and CD206+ cells) were markedly observed in the central area of the spongiotic epidermis of skin lesions in all AD patients. Furthermore, IgE-positive IDECs with HDM antigens in the central areas of the spongiosis were found in four of the six (66.7%) AD patients. Langerhans cells (LCs; CD207+ cells) with HDM antigens were also observed in the peripheral areas of the spongiosis. Infiltration of CD4+ and CD8+ T cells in association with IgE-positive IDECs and LCs with HDM antigens was seen in the spongiotic epidermis. An IgE-mediated delayed-type hypersensitivity reaction, in combination with IgE-bearing dendritic cells, specific T cells, keratinocytes, and HDM antigens, may lead to spongiotic tissue formation in eczematous dermatitis in AD.

scholarly journals Bee Venom Phospholipase A2 Ameliorates House Dust Mite Extract Induced Atopic Dermatitis Like Skin Lesions in Mice

Toxins ◽  
2017 ◽  
Vol 9 (2) ◽  
pp. 68 ◽  
Author(s):  
Kyung-Hwa Jung ◽  
Hyunjung Baek ◽  
Manho Kang ◽  
Namsik Kim ◽  
Seung Lee ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Phospholipase A2 ◽  
House Dust ◽  
House Dust Mite ◽  
Skin Lesions ◽  
Bee Venom ◽  
Mite Extract ◽  
Dust Mite ◽  
House Dust Mite Extract

Atopic dermatitis, house-dust mite, and the placebo effect

Allergy ◽  
2001 ◽  
Vol 56 (12) ◽  
pp. 1226-1226 ◽  
Author(s):  
C. Gutgesell ◽  
S. Heise ◽  
S. Seubert ◽  
A. Seubert ◽  
S. Domhof ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Placebo Effect ◽  
House Dust ◽  
House Dust Mite ◽  
Dust Mite
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