Relative bioavailability of cyclosporin from conventional and microemulsion formulations in heart-lung transplant candidates with cystic fibrosis

1995 ◽  
Vol 48-48 (3-4) ◽  
Author(s):  
K.K.C. Tan ◽  
J.A. Uttridge ◽  
A.K. Trull ◽  
J. Wallwork
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplant ◽  
Relative Bioavailability ◽  
Heart Lung Transplant ◽  
Transplant Candidates

CYCLOSPORINE BIOAVAILABILITY IN HEART-LUNG TRANSPLANT CANDIDATES WITH CYSTIC FIBROSIS

1990 ◽  
Vol 49 (4) ◽  
pp. 821-822 ◽  
Author(s):  
STEPHEN D. NIMER ◽  
ALLEN L. MILEWICZ ◽  
RICHARD E. CHAMPLIN ◽  
RONALD W. BUSUTTIL
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplant ◽  
Heart Lung Transplant ◽  
Transplant Candidates

Physician Refusal of Requests for Futile or Ineffective Interventions

1992 ◽  
Vol 1 (2) ◽  
pp. 127-134 ◽  
Author(s):  
John J. Paris ◽  
Frank E. Reardon
Keyword(s):  
Cystic Fibrosis ◽  
Respiratory Failure ◽  
Young Patient ◽  
Lung Transplant ◽  
Medical Literature ◽  
Heart Lung Transplant ◽  
Physician Compliance ◽  
Transplant Center ◽  
The Family ◽  
Cross Country

Several recent articles raise an issue long unaddressed in the medical literature: physician compliance with patient or family requests for futile or ineffectice therapy. Although they agree philosophically that such treatment ought not be given, most physicians have followed the course described by Stanley Fiel, in which a young patient dying of cystic fibrosis was accepted “for evaluation” by a transplant center even though he has already passed the threshold of viability as a candidate for a heart-lung transplant. Dr. Fiel reported this action was taken not in the hope of doing the transplant but so that the family could assure themselves they had done “everything possible.” The patient, after a long and stressful cross-country flight, arrived at the hospital in respiratory failure. He died soon thereafter far from home and familiar surroundings.

Exercise testing in pediatric lung transplant candidates with cystic fibrosis

2011 ◽  
Vol 15 (3) ◽  
pp. 294-299 ◽  
Author(s):  
Thomas Radtke ◽  
Albert Faro ◽  
Jackson Wong ◽  
Annette Boehler ◽  
Christian Benden
Keyword(s):  
Cystic Fibrosis ◽  
Exercise Testing ◽  
Lung Transplant ◽  
Transplant Candidates

Altered Pharmacokinetics of Cyclosporin in Heart-Lung Transplant Recipients with Cystic Fibrosis

1990 ◽  
Vol 12 (6) ◽  
pp. 520-524 ◽  
Author(s):  
K. K. C. Tan ◽  
K. L. Hue ◽  
S. E. Strickland ◽  
A. K. Trull ◽  
R. L. Smyth ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplant ◽  
Transplant Recipients ◽  
Heart Lung Transplant ◽  
Lung Transplant Recipients

Cyclosporin pharmacokinetics in heart-lung transplant recipients with cystic fibrosis

1994 ◽  
Vol 46 (3) ◽  
Author(s):  
V.T. Tsang ◽  
A. Johnston ◽  
F. Heritier ◽  
N. Leaver ◽  
M.E. Hodson ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplant ◽  
Transplant Recipients ◽  
Heart Lung Transplant ◽  
Lung Transplant Recipients

scholarly journals Colonisation of lung allografts with Pseudomonas aeruginosa in heart-lung transplant recipients with cystic fibrosis.

Thorax ◽  
1994 ◽  
Vol 49 (7) ◽  
pp. 721-722 ◽  
Author(s):  
V Tsang ◽  
T L Pitt ◽  
M E Kaufmann ◽  
H Gaya ◽  
M E Hodson ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Pseudomonas Aeruginosa ◽  
Lung Transplant ◽  
Transplant Recipients ◽  
Heart Lung Transplant ◽  
Lung Transplant Recipients

scholarly journals Telerehabilitation Using Fitness Application in Patients with Severe Cystic Fibrosis Awaiting Lung Transplant: A Pilot Study

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Aimee M. Layton ◽  
Andrew M. Irwin ◽  
Erin C. Mihalik ◽  
Emily Fleisch ◽  
Claire L. Keating ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Adverse Events ◽  
Lung Transplant ◽  
Exercise Program ◽  
Text Messages ◽  
Data Set ◽  
Home Based ◽  
Viable Solution ◽  
Transplant Candidates ◽  
Fitness Application

Purpose. The purpose of this study was to pilot a home-based pulmonary rehabilitation (PR) program administered via a telemedicine approach using a combination of fitness application and self-selected activity in lung transplant candidates with cystic fibrosis (CF). Methods. We recruited adult patients with CF. The main outcome was adherence, measured by number of sessions completed in 12 weeks. Secondary outcomes were adverse events, six-minute walk distance (6MWD), and dyspnea. Participants were provided a personalized exercise program and equipment including a fitness application that provided exercise videos, recorded exercise time, and corresponding heart rate. We reviewed data daily and provided text messages with feedback. We compared our study outcomes to a retrospective data set of CF patients who participated in a 24-session outpatient hospital-based PR program. Data presented as mean ± standard   deviation . Results. Eleven patients participated in the home PR program, 45% female, age 33 ± 7   years , FEV1 27 ± 5 % predicted. Sessions completed were 19 ± 12 home-based PR vs. 9 ± 4 hospital-based PR, p = .03 . Fifty percent of the home-based group completed ≥24 sessions in 12 weeks versus 0% of the hospital-based patients ( p = .03 ). There were no adverse events during exercise. Completers of the home-based program demonstrated a clinically meaningful lower decline in 6 MWD than noncompleters (6MWD − 7 ± 15 vs. − 86 ± 108   meters ). Only one participant performed a post 6 MWD in the hospital-based PR. Conclusion. Patients with severe CF demonstrated adherence to home PR delivered using fitness application and self-selected activity with no adverse events. This program style may be a viable solution for telerehabilitation in severe CF and is particularly relevant in the COVID era.

RAD in stable lung and heart/lung transplant recipients: safety, tolerability, pharmacokinetics, and impact of cystic fibrosis

2001 ◽  
Vol 20 (3) ◽  
pp. 330-339 ◽  
Author(s):  
Ramona L Doyle ◽  
Marshall I Hertz ◽  
Jordan M Dunitz ◽  
J.E Loyd ◽  
Arlene A Stecenko ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplant ◽  
Transplant Recipients ◽  
Heart Lung Transplant ◽  
Lung Transplant Recipients

Pharmacokinetics of cyclosporine in heart and lung transplant candidates and recipients with cystic fibrosis and Eisenmenger's syndrome

1993 ◽  
Vol 53 (5) ◽  
pp. 544-554 ◽  
Author(s):  
Keith K C Tan ◽  
Andrew K Trull ◽  
Karen L Hue ◽  
Nicola G Best ◽  
John Wallwork ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplant ◽  
Eisenmenger’S Syndrome ◽  
Transplant Candidates
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