Plasma sorbitol dehydrogenase, glutamate dehydrogenase, and alkaline phosphatase as potential indicators of liver intoxication in grey mullet (Mugil auratus Risso)

1993 ◽  
Vol 50 (4) ◽  
pp. 586-592 ◽  
Author(s):  
B. Ozretić ◽  
M. Krajnović-Ozretić
Keyword(s):  
Alkaline Phosphatase ◽  
Glutamate Dehydrogenase ◽  
Sorbitol Dehydrogenase ◽  
Grey Mullet ◽  
Liver Intoxication

Haematological and serum chemistry profiles of ferrets (Mustela putorius furo)

1982 ◽  
Vol 16 (2) ◽  
pp. 133-137 ◽  
Author(s):  
Elsbeth J. Lee ◽  
W. E. Moore ◽  
H. C. Fryer ◽  
H. C. Minocha
Keyword(s):  
Alkaline Phosphatase ◽  
Weight Gain ◽  
Total Protein ◽  
Alanine Aminotransferase ◽  
Inorganic Phosphate ◽  
Sorbitol Dehydrogenase ◽  
Serum Chemistry ◽  
Mustela Putorius ◽  
Mustela Putorius Furo

Female, male and castrated male ferrets were studied. Weight gain plateaued at 28-weeks of age with males about 500 g heavier than females. No statistically significant differences in haematology were observed with age, but alkaline phosphatase and alanine aminotransferase levels fell while glucose increased. Haemolysis led to various changes including marked increases in total protein, albumin, inorganic phosphate and sorbitol dehydrogenase.

Value of alkaline phosphatase, 5'-nucleotidase, gamma-glutamyltransferase, and glutamate dehydrogenase activity measurements (single and combined) in serum in diagnosis of metastasis to the liver.

1977 ◽  
Vol 23 (11) ◽  
pp. 2034-2038 ◽  
Author(s):  
N K Kim ◽  
W G Yasmineh ◽  
E F Freier ◽  
A I Goldman ◽  
A Theologides
Keyword(s):  
Alkaline Phosphatase ◽  
Liver Metastases ◽  
Glutamate Dehydrogenase ◽  
False Positive ◽  
Serum Alkaline Phosphatase ◽  
False Negative ◽  
Diagnostic Value ◽  
Gamma Glutamyltransferase ◽  
Activity Measurements ◽  
Positive Results

Abstract We assessed, in 98 patients with cancer, the diagnostic value of measuring serum alkaline phosphatase, 5'-nucleotidase, gamma-glutamyltransferase, and glutamate dehydrogenase activities as an aid to detection of liver metastases. All four enzymes showed diagnostic value, but 5'-nucleotidase appeared to have the greatest. It showed the lowest false-positive results (7.4%) with the highest predictive value of a positive test (85.7%) and agreement (81.3%).. gamma-Glutamyltransferase showed the lowest proportion of false-negative results (2.8%), but was the least specific 35% false-positive results). Analysis of various test combinations showed that the best agreement (77.5%) was obtained when the patients were divided into those who had no or only one abnormal test result, and those who had two or more abnormal test results. However, this was not better than the agreement for 5' nucleotidase alone (81.3%). The agreement of 5'-nucleotidase and gamma-glutamyltransferase (i.e., both tests were positive or negative) was excellent (91.4%), but such agreement included only 67% of the patients with liver metastases.

scholarly journals Sensibilité des Chèvres à une réinfestation homologue par Fasciola gigantica in goats

1991 ◽  
Vol 44 (1) ◽  
pp. 69-73
Author(s):  
I.A. Goraish ◽  
E.B. Abdelsalam ◽  
G. Tartour
Keyword(s):  
Glutamate Dehydrogenase ◽  
Fasciola Gigantica ◽  
Sorbitol Dehydrogenase

Des chèvres infestées auparavant avec 100 métacercaires vivants de Fasciola gigantica et traitées avec du rafoxanide (Ranide, 7,5 mg/kg) à la quatrième semaine n'ont pas été protégées contre une invasion homologue de 250 métacercaires administrés deux semaines plus tard. La réinfestation s'est traduite par des lésions hépatiques plus sévères et un fort pourcentage de trématodes a été retrouvé par rapport à la première infestation. Cependant, la taille des trématodes de la seconde infestation (épreuve) était considérablement réduite. L'activité de l'enzyme plasmatique de l'aspartate amino-transférase (AST), du glutamate-dehydrogénase (GD) et du sorbitol déhydrogénase (SD) s'est élevée à un niveau comparable au cours des deux infestations. Cependant, la réponse des anticorps plasmatiques de F. gigantica était moins prononcée chez les chèvres réinfestées.

Constancy of enzyme electrofocusing patterns in a stand of the lichen Umbilicaria mammulata

1986 ◽  
Vol 64 (9) ◽  
pp. 1928-1934 ◽  
Author(s):  
C. Hageman ◽  
D. Fahselt
Keyword(s):  
Alkaline Phosphatase ◽  
Superoxide Dismutase ◽  
Glutamate Dehydrogenase ◽  
Isocitrate Dehydrogenase ◽  
Mannitol Dehydrogenase ◽  
Specific Staining ◽  
Phosphogluconate Dehydrogenase ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
Sampling Times ◽  
Umbilicaria Mammulata

Thalli of the lichen Umbilicaria mammulata (Ach.) Tuck, were collected from one site, 24 at each of five different sampling times, over a period of 1 year. Protein extracts from each individual thallus were subjected to isoelectric focusing, followed by specific staining for eight enzyme systems (mannitol dehydrogenase, isocitrate dehydrogenase, 6-phosphogluconate dehydrogenase, glucose-6-phosphate dehydrogenase, glutamate dehydrogenase, superoxide dismutase, esterase, and alkaline phosphatase). A total of 55 bands were resolved, 25 of which were constant in all thalli through all sampling dates. Principal components analysis of the electromorph data showed the existence of groups corresponding to sets of thalli collected at the same times; esterase and alkaline phosphatase variation were primarily responsible for these groupings. Banding patterns of 6-phosphogluconate dehydrogenase and superoxide dismutase were constant regardless of date of collection. Most bands of glucose-6-phosphate dehydrogenase and glutamate dehydrogenase were consistent through all sampling times, but each system exhibited one band that differed in frequency from one collection date to another. Electromorphs of mannitol dehydrogenase and isocitrate dehydrogenase exhibited only minor variability. Dehydrogenase enzymes, since they tended to vary least from one sampling time to the next, can thus be used more readily for taxonomic purposes. If esterases and alkaline phosphatases are to be applied as taxonomic criteria, samples for comparison should be collected simultaneously.

Glutamate Dehydrogenase and Alkaline Phosphatase as Very Early Predictors of Hepatocellular Carcinoma Recurrence after Liver Transplantation

Digestion ◽  
2015 ◽  
Vol 91 (2) ◽  
pp. 117-127 ◽  
Author(s):  
Katja Piras-Straub ◽  
Khaleda Khairzada ◽  
Guido Gerken ◽  
Fuat Saner ◽  
J�rgen Treckmann ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Alkaline Phosphatase ◽  
Glutamate Dehydrogenase ◽  
Early Predictors ◽  
Hepatocellular Carcinoma Recurrence

scholarly journals Pregnancy-associated changes of serum biochemical values in Lipizzaner broodmares

2015 ◽  
Vol 63 (3) ◽  
pp. 303-316 ◽  
Author(s):  
Boglárka Vincze ◽  
Orsolya Kutasi ◽  
Ferenc Baska ◽  
Ottó Szenci
Keyword(s):  
Alkaline Phosphatase ◽  
Glutamate Dehydrogenase ◽  
Reference Values ◽  
Total Protein ◽  
Biochemical Parameters ◽  
Clinical Chemistry ◽  
Venous Blood ◽  
Serum Triglyceride ◽  
Control Group ◽  
Aspartate Transaminase

The aims of this study were to detect physiological changes in blood biochemical parameters throughout gestation, to compare the findings in nonpregnant and pregnant Lipizzaner mares in early-mid and late pregnancy, and to provide reference values for clinical chemistry parameters in this horse breed. A total of 136 venous blood samples were collected from 20 pregnant and 10 nonpregnant (control) asymptomatic Lipizzaner broodmares for biochemical analyses. Twelve parameters (albumin, total protein, urea, triglycerides, glucose, creatinine, alkaline phosphatase, aspartate transaminase, glutamate dehydrogenase, gammaglutamyltransferase, creatine kinase and lactate dehydrogenase) were measured. For the statistical analyses, correlation, analysis of variance and Kruskal–Wallis H-test were used to evaluate the possible associations between parameters. Serum triglyceride levels proved to be significantly different in pregnant mares compared to the control group. Total protein and urea levels significantly decreased, while glucose, triglyceride and glutamate dehydrogenase values increased from approx. the fifth month of gestation until parturition. Four biochemical parameters (albumin, aspartate transaminase, total protein and urea) were lower and three other variables (glucose, alkaline phosphatase and creatinine) were significantly higher in late-term pregnant mares than in mares in early or mid-gestation. It is concluded that reference values not only reflect the species, breed and sex but also the reproductive status of animals.

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