Intensity-related changes in cochlear blood flow in the guinea pig during and following acoustic exposure

1993 ◽  
Vol 250 (5) ◽  
Author(s):  
F. Scheibe ◽  
H. Haupt ◽  
C. Ludwig
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Cochlear Blood Flow ◽  
Acoustic Exposure

scholarly journals Lipopolysaccharide decreases cochlear blood flow dose dependently in a guinea pig animal model via TNF signaling

2021 ◽  
Author(s):  
Friedrich Ihler ◽  
Saskia Freytag ◽  
Benedikt Kloos ◽  
Jennifer Lee Spiegel ◽  
Frank Haubner ◽  
...  
Keyword(s):  
Animal Model ◽  
Blood Flow ◽  
Guinea Pig ◽  
Cochlear Blood Flow ◽  
Pig Animal Model

Effects of Electrical Stimulation of the Superior Cervical Ganglion on Cochlear Blood Flow in Guinea Pig

1993 ◽  
Vol 113 (2) ◽  
pp. 146-151 ◽  
Author(s):  
Tian-Ying Ren ◽  
E. Laurikainen ◽  
W. S. Quirk ◽  
J. M. Miller ◽  
A. L. Nuttall
Keyword(s):  
Blood Flow ◽  
Electrical Stimulation ◽  
Guinea Pig ◽  
Superior Cervical Ganglion ◽  
Cochlear Blood Flow ◽  
Cervical Ganglion ◽  
Stimulation Of

scholarly journals Neuronal regulation of cochlear blood flow in the guinea-pig.

1994 ◽  
Vol 480 (3) ◽  
pp. 563-573 ◽  
Author(s):  
E A Laurikainen ◽  
O Costa ◽  
J M Miller ◽  
A L Nuttall ◽  
T Y Ren ◽  
...  
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Cochlear Blood Flow ◽  
Neuronal Regulation

Guinea Pig Cochlear Blood Flow under Definite Sound Exposure-Hydrogen Clearance Measurement

ORL ◽  
1991 ◽  
Vol 53 (6) ◽  
pp. 327-330 ◽  
Author(s):  
P. Meyer ◽  
K.-D. Kuhl ◽  
R. Schmidt ◽  
W. Grützmacher
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Cochlear Blood Flow ◽  
Sound Exposure ◽  
Hydrogen Clearance

Effects of Perilymph Volume Adjustments on Cochlear Blood Flow in the Guinea Pig

1991 ◽  
Vol 111 (1) ◽  
pp. 94-100 ◽  
Author(s):  
G. M. McLaren ◽  
H. A. Dengerink ◽  
P. A. Hellstrom ◽  
J. W. Wright
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Cochlear Blood Flow

Blood Pressure and Cochlear Blood Flow in the Guinea Pig

1989 ◽  
Vol 107 (5-6) ◽  
pp. 413-416 ◽  
Author(s):  
M. Hasegawa ◽  
K. Yokoyama ◽  
N. Kobayashi ◽  
A. Okamoto ◽  
T. Tamura ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Guinea Pig ◽  
Cochlear Blood Flow

Laser-Doppler Measurements and Electrocochleography during Ischemia of the Guinea Pig Cochlea: Implications for Hearing Preservation in Acoustic Neuroma Surgery

1993 ◽  
Vol 102 (2) ◽  
pp. 127-136 ◽  
Author(s):  
Robert Aaron Levine ◽  
Nicolas Bu-Saba ◽  
M. Christian Brown
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Acoustic Neuroma ◽  
Compound Action Potential ◽  
Hearing Preservation ◽  
Laser Doppler ◽  
Otic Capsule ◽  
Doppler Measurement ◽  
Cochlear Blood Flow ◽  
Acoustic Neuroma Surgery

Interruption of cochlear blood flow has been implicated as one of the causes of the sensorineural hearing loss that may occur during acoustic neuroma surgery. With the guinea pig as an animal model for cerebellopontine angle surgery, laser-Doppler measurements were used to estimate the cochlear blood flow changes caused by compression of the eighth nerve complex. With compression, the laser-Doppler measurements decreased abruptly; somewhat later, the electrocochleographic potentials declined. When compression was released, laser-Doppler measurements usually returned immediately, followed later by return of the electrical potentials. Some of these potentials, including the compound action potential of the auditory nerve, often became transiently larger than their precompression values. Interposing bone between the laser-Doppler probe and the otic capsule, so that the total bone thickness approximated the thickness of the human otic capsule, decreased the laser-Doppler measurement, but changes caused by compression were still apparent. Thus, although the human otic capsule is much thicker than the guinea pig capsule, it may still be possible to make laser-Doppler estimates of human cochlear blood flow. Laser-Doppler monitoring during acoustic neuroma surgery may be beneficial, because it could give earlier warning of ischemia than is currently available from electrocochleographic monitoring, thereby enabling earlier corrective action. Electrocochleography complements laser-Doppler measurements by indicating the physiologic state of the cochlea.

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