Rat T-cell receptor ? chain sequences: identification of conserved gene segments and a unique chimeric constant region gene, C4L

1994 ◽  
Vol 40 (6) ◽  
Author(s):  
Miyuki Kinebuchi ◽  
Kokichi Kikuchi ◽  
Akihiro Matsuura
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
Constant Region ◽  
Region Gene ◽  
Constant Region Gene ◽  
Receptor Chain ◽  
Conserved Gene

scholarly journals A unique RFLP in the human T-cell receptor γ constant region gene TRGC1

1989 ◽  
Vol 17 (1) ◽  
pp. 471-471 ◽  
Author(s):  
N. Ghanem ◽  
C. Buresi ◽  
G. Lefranc ◽  
M.-P. Lefranc
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
Constant Region ◽  
Region Gene ◽  
Human T Cell ◽  
Constant Region Gene

Sequence and diversity of rat T-cell receptor ?-chain-encoding genes

1994 ◽  
Vol 39 (2) ◽  
Author(s):  
Carine Tischmann ◽  
Ulrich Feige ◽  
Doris R�egg ◽  
Jill Gasser ◽  
Gerd Pluschke
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
Receptor Chain ◽  
Encoding Genes

scholarly journals T-cell receptor chain Vbeta subunit staining to quantify the malignant clone in adult T-cell leukemia

Retrovirology ◽  
2015 ◽  
Vol 12 (S1) ◽  
Author(s):  
Aileen G Rowan ◽  
Paul Fields ◽  
Graham P Taylor ◽  
Charles RM Bangham
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia ◽  
Receptor Chain

Sequence analysis of bovine T-cell receptor ? chain

1990 ◽  
Vol 31 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Naotaka Ishiguro ◽  
Astuko Tanaka ◽  
Morikazu Shinagawa
Keyword(s):  
T Cell ◽  
Sequence Analysis ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
Receptor Chain

scholarly journals Identification of the pre-T-cell receptor   chain in nonmammalian vertebrates challenges the structure-function of the molecule

2010 ◽  
Vol 107 (46) ◽  
pp. 19991-19996 ◽  
Author(s):  
P. Smelty ◽  
C. Marchal ◽  
R. Renard ◽  
L. Sinzelle ◽  
N. Pollet ◽  
...  
Keyword(s):  
T Cell ◽  
Structure Function ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
Receptor Chain

scholarly journals Pre-depletion of TRBC1+ T cells promotes the therapeutic efficacy of anti-TRBC1 CAR-T for T-cell malignancies

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Chaoting Zhang ◽  
Heyilimu Palashati ◽  
Zhuona Rong ◽  
Ningjing Lin ◽  
Luyan Shen ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
T Cell Receptor ◽  
Therapeutic Efficacy ◽  
Terminal Differentiation ◽  
Cell Receptor ◽  
Constant Region ◽  
Car T ◽  
T Cell Malignancies ◽  
Β Chain

AbstractTargeting T cell receptor β-chain constant region 1 (TRBC1) CAR-T could specifically kill TRBC1+ T-cell malignancies. However, over-expressed CARs on anti-TRBC1 CAR transduced TRBC1+ T cells (CAR-C1) bound to autologous TRBC1, masking TRBC1 from identification by other anti-TRBC1 CAR-T, and moreover only the remaining unoccupied CARs recognized TRBC1+ cells, considerably reducing therapeutic potency of CAR-C1. In addition, co-culture of anti-TRBC1 CAR-T and TRBC1+ cells could promote exhaustion and terminal differentiation of CAR-T. These findings provide a rationale for pre-depleting TRBC1+ T cells before anti-TRBC1 CAR-T manufacturing.

A Highly Conserved Phenylalanine in the alpha, beta-T Cell Receptor (TCR) Constant Region Determines the Integrity of TCR/CD3 Complexes

1994 ◽  
Vol 40 (3) ◽  
pp. 323-336 ◽  
Author(s):  
S. CASPAR-BAUGUIL ◽  
J. ARNAUD ◽  
A. HUCHENQ ◽  
W. R. HEIN ◽  
C. GEISLER ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
Constant Region ◽  
Alpha Beta
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