D-Lactic acidosis, a life-threatening complication in short-bowel syndrome

1992 ◽  
Vol 7 (3) ◽  
Author(s):  
Esther Granot ◽  
Khalil Abu-Dalu ◽  
Medad Schiller
Keyword(s):  
Lactic Acidosis ◽  
Short Bowel Syndrome ◽  
Short Bowel ◽  
Life Threatening ◽  
Life Threatening Complication

In Reply: D-Lactic Acidosis in Patients with Short Bowel Syndrome

1995 ◽  
Vol 41 (5) ◽  
pp. 768-769 ◽  
Author(s):  
Ger Bongaerts ◽  
Jules Tolboom ◽  
Ton Naber ◽  
Jan Bakkeren ◽  
René Severijnen ◽  
...  
Keyword(s):  
Lactic Acidosis ◽  
Short Bowel Syndrome ◽  
Short Bowel

D-lactic acidosis in short-bowel syndrome managed with antibiotics and probiotics

2004 ◽  
Vol 39 (4) ◽  
pp. 634-636 ◽  
Author(s):  
Hiroo Uchida ◽  
Hideki Yamamoto ◽  
Yoshiyuki Kisaki ◽  
Junko Fujino ◽  
Yuki Ishimaru ◽  
...  
Keyword(s):  
Lactic Acidosis ◽  
Short Bowel Syndrome ◽  
Short Bowel

PP096-MON A RARE COMPLICATION OF SHORT BOWEL SYNDROME: D-LACTIC ACIDOSIS

2011 ◽  
Vol 6 (1) ◽  
pp. 151
Author(s):  
M.J. Tapia ◽  
R. Fernandez ◽  
C. Maldonado ◽  
C. Bautista ◽  
D. Fernandez-Arias ◽  
...  
Keyword(s):  
Lactic Acidosis ◽  
Short Bowel Syndrome ◽  
Rare Complication ◽  
Short Bowel

Fecal Transplantation Successfully Treats Recurrent D-Lactic Acidosis in a Child With Short Bowel Syndrome

2015 ◽  
Vol 41 (5) ◽  
pp. 896-897 ◽  
Author(s):  
Zev H. Davidovics ◽  
Katherine Vance ◽  
Nancy Etienne ◽  
Jeffrey S. Hyams
Keyword(s):  
Lactic Acidosis ◽  
Short Bowel Syndrome ◽  
Fecal Transplantation ◽  
Short Bowel

scholarly journals D-Lactic acidosis in a boy with short bowel syndrome.

1980 ◽  
Vol 55 (10) ◽  
pp. 810-812 ◽  
Author(s):  
E P Schoorel ◽  
M A Giesberts ◽  
W Blom ◽  
H H van Gelderen
Keyword(s):  
Lactic Acidosis ◽  
Short Bowel Syndrome ◽  
Short Bowel

d -lactic acidosis in children with short bowel syndrome who underwent autologous bowel reconstruction: A retrospective study

2017 ◽  
Vol 49 (4) ◽  
pp. e282-e283
Author(s):  
F. Chiatto ◽  
R. Coletta ◽  
A. Morabito ◽  
A. Aversano ◽  
L. Forsythe
Keyword(s):  
Retrospective Study ◽  
Lactic Acidosis ◽  
Short Bowel Syndrome ◽  
Short Bowel

D-lactic Acidosis in Children with Short Bowel Syndrome

2017 ◽  
Vol 101 ◽  
pp. S133
Author(s):  
Fabrizia Chiatto ◽  
Lynette Forsythe ◽  
Riccardo Coletta ◽  
Valeria Solari ◽  
Bashar Alseiri ◽  
...  
Keyword(s):  
Lactic Acidosis ◽  
Short Bowel Syndrome ◽  
Short Bowel

scholarly journals D-Lactic Acidosis: An Underrecognized Complication of Short Bowel Syndrome

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
N. Gurukripa Kowlgi ◽  
Lovely Chhabra
Keyword(s):  
Lactic Acid ◽  
Lactic Acidosis ◽  
Short Bowel Syndrome ◽  
Laboratory Data ◽  
Lactate Production ◽  
Rare Condition ◽  
Short Bowel ◽  
Colonic Flora ◽  
Acid Accumulation ◽  
History Of

D-lactic acidosis or D-lactate encephalopathy is a rare condition that occurs primarily in individuals who have a history of short bowel syndrome. The unabsorbed carbohydrates act as a substrate for colonic bacteria to form D-lactic acid among other organic acids. The acidic pH generated as a result of D-lactate production further propagates production of D-lactic acid, hence giving rise to a vicious cycle. D-lactic acid accumulation in the blood can cause neurologic symptoms such as delirium, ataxia, and slurred speech. Diagnosis is made by a combination of clinical and laboratory data including special assays for D-lactate. Treatment includes correcting the acidosis and decreasing substrate for D-lactate such as carbohydrates in meals. In addition, antibiotics can be used to clear colonic flora. Although newer techniques for diagnosis and treatment are being developed, clinical diagnosis still holds paramount importance, as there can be many confounders in the diagnosis as will be discussed subsequently.

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