Calcium dependency of the AT1-receptor mediated effects in the rat portal vein: influence of calcium antagonists

1994 ◽  
Vol 349 (4) ◽  
pp. 437-442 ◽  
Author(s):  
J. S. Zhang ◽  
J. C. A. Van Meel ◽  
M. Pfaffendorf ◽  
P. A. Van Zwieten
Keyword(s):  
Portal Vein ◽  
Calcium Antagonists ◽  
At1 Receptor ◽  
Calcium Dependency ◽  
Mediated Effects ◽  
Rat Portal Vein

VASODILATORS AND CALCIUM-45 UPTAKE IN VASCULAR SMOOTH AND CARDIAC MUSCLE

1981 ◽  
Vol 9 (2) ◽  
pp. 139P-139P
Author(s):  
STIG-LENNART BOSTROM ◽  
BENGT LJUNG
Keyword(s):  
Cell Membrane ◽  
Portal Vein ◽  
Cardiac Muscle ◽  
Cellular Uptake ◽  
Papillary Muscle ◽  
Calcium Antagonists ◽  
Contractile Activity ◽  
Rat Portal Vein ◽  
Ic50 Values

A variety of substances, chemically heterogenous, has been classified as calcium antagonists. They inhibit the contractile activity of vascular smooth and cardiac muscle. This has been attributed to a blockade of the so called slow channels of the cell membrane causing an inhibition of the transmembrane influx of calcium. In the experiments reported we have studied the effect of verapamil, nifedipine and felodipine (pINN) on the uptake of calcium-45 in the rat portal vein and papillary muscle. The results show that the substances, at their IC50 values, did not decrease the cellular uptake of calcium-45, measured with the lanthanum method.

Endothelium dependent expression and underlying mechanisms of des-Arg9-bradykinin-induced B1R-mediated vasoconstriction in rat portal vein

Peptides ◽  
2012 ◽  
Vol 37 (2) ◽  
pp. 216-224 ◽  
Author(s):  
Fernanda L. Basei ◽  
Daniela A. Cabrini ◽  
Cláudia P. Figueiredo ◽  
Stefânia Forner ◽  
Daniela B. Hara ◽  
...  
Keyword(s):  
Portal Vein ◽  
Rat Portal Vein ◽  
Underlying Mechanisms

Effect of Glibenclamide on Membrane Response to Metabolic Inhibition in Smooth Muscle of Rat Portal Vein

1994 ◽  
Vol 31 (2) ◽  
pp. 82-91 ◽  
Author(s):  
Marie-Louise Lydrup ◽  
Karl Swärd ◽  
Per Hellstrand
Keyword(s):  
Smooth Muscle ◽  
Portal Vein ◽  
Metabolic Inhibition ◽  
Rat Portal Vein
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