The behavioural responses to 8-OH-DPAT, ipsapirone and the novel 5-HT1A receptor agonist Bay Vq 7813 in the pig

1990 ◽  
Vol 342 (3) ◽  
Author(s):  
Wolfgang L�scher ◽  
Ulrike Witte ◽  
Gabriele Fredow ◽  
J�rg Traber ◽  
Thomas Glaser
Keyword(s):  
Receptor Agonist ◽  
The Novel ◽  
Behavioural Responses

58-OR: The Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide Transiently Delays Gastric Emptying Similarly to a Selective Long-Acting GLP-1 Receptor Agonist

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 58-OR ◽  
Author(s):  
SHWETA URVA ◽  
MICHAEL A. NAUCK ◽  
TAMER COSKUN ◽  
XUEWEI CUI ◽  
AXEL HAUPT ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Receptor Agonist ◽  
The Novel ◽  
Long Acting

scholarly journals Four stereoisomers of the novel μ-opioid receptor agonist tapentadol hydrochloride

2011 ◽  
Vol 67 (2) ◽  
pp. o71-o76 ◽  
Author(s):  
Krishnan Ravikumar ◽  
Balasubramanian Sridhar ◽  
Nitin Pradhan ◽  
Mayur Khunt
Keyword(s):  
Opioid Receptor ◽  
Receptor Agonist ◽  
The Novel ◽  
Opioid Receptor Agonist ◽  
Μ Opioid Receptor

Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271

2003 ◽  
Vol 989 (1) ◽  
pp. 99-111 ◽  
Author(s):  
Frank Mauler ◽  
Volker Hinz ◽  
Karl-Heinz Augstein ◽  
Marion Faßbender ◽  
Ervin Horváth
Keyword(s):  
Brain Edema ◽  
Receptor Agonist ◽  
Cannabinoid Receptor ◽  
The Novel

scholarly journals Inhibitory activity of the novel CB2 receptor agonist, GW833972A, on guinea-pig and human sensory nerve function in the airways

2008 ◽  
Vol 155 (4) ◽  
pp. 547-557 ◽  
Author(s):  
M G Belvisi ◽  
H J Patel ◽  
V Freund-Michel ◽  
D J Hele ◽  
N Crispino ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Inhibitory Activity ◽  
Receptor Agonist ◽  
Sensory Nerve ◽  
The Novel ◽  
Nerve Function ◽  
Cb2 Receptor

scholarly journals Predicting behavioural responses to novel organisms: state-dependent detection theory

2017 ◽  
Vol 284 (1847) ◽  
pp. 20162108 ◽  
Author(s):  
Pete C. Trimmer ◽  
Sean M. Ehlman ◽  
Andrew Sih
Keyword(s):  
Environmental Change ◽  
Signal Detection Theory ◽  
Novel Species ◽  
Detection Theory ◽  
The Novel ◽  
Natural Habitats ◽  
Behavioural Responses ◽  
State Dependent ◽  
Optimal Thresholds ◽  
Adaptive Thresholds

Human activity alters natural habitats for many species. Understanding variation in animals' behavioural responses to these changing environments is critical. We show how signal detection theory can be used within a wider framework of state-dependent modelling to predict behavioural responses to a major environmental change: novel, exotic species. We allow thresholds for action to be a function of reserves, and demonstrate how optimal thresholds can be calculated. We term this framework ‘state-dependent detection theory’ (SDDT). We focus on behavioural and fitness outcomes when animals continue to use formerly adaptive thresholds following environmental change. In a simple example, we show that exposure to novel animals which appear dangerous—but are actually safe—(e.g. ecotourists) can have catastrophic consequences for ‘prey’ (organisms that respond as if the new organisms are predators), significantly increasing mortality even when the novel species is not predatory. SDDT also reveals that the effect on reproduction can be greater than the effect on lifespan. We investigate factors that influence the effect of novel organisms, and address the potential for behavioural adjustments (via evolution or learning) to recover otherwise reduced fitness. Although effects of environmental change are often difficult to predict, we suggest that SDDT provides a useful route ahead.

The Novel Dual GLP-1/GIP Receptor Agonist DA-CH5 Is Superior to Single GLP-1 Receptor Agonists in the MPTP Model of Parkinson’s Disease

2020 ◽  
Vol 10 (2) ◽  
pp. 523-542 ◽  
Author(s):  
Lingyu Zhang ◽  
Liping Zhang ◽  
Yanwei Li ◽  
Lin Li ◽  
Josefine Ulrikke Melchiorsen ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Receptor Agonist ◽  
The Novel ◽  
Receptor Agonists ◽  
Mptp Model ◽  
Gip Receptor

scholarly journals The novel cannabinoid CB 1 receptor agonist AM11101 increases food intake in female rats

2019 ◽  
Vol 176 (20) ◽  
pp. 3972-3982 ◽  
Author(s):  
Sean B. Ogden ◽  
Michael S. Malamas ◽  
Alexandros Makriyannis ◽  
Lisa A. Eckel
Keyword(s):  
Food Intake ◽  
Receptor Agonist ◽  
Female Rats ◽  
The Novel
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