Comparison of various spasmolytic drugs on guinea-pig isolated common bile duct

1991 ◽  
Vol 344 (1) ◽  
Author(s):  
Martin Pfaffendorf ◽  
Martina Moormann ◽  
Franke Sponholz
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Guinea Pig

Morpho-functional evidence for tachykinins as major non-cholinergic excitatory transmitters in the guinea pig common bile duct (CBD)

1998 ◽  
Vol 114 ◽  
pp. A519
Author(s):  
R. DeGiorgio ◽  
R. Patacchini ◽  
L. Barthò ◽  
G. Barbara ◽  
V. Villani ◽  
...  
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Guinea Pig

Influence of indomethacin on effects of endothelin-1 on guinea pig isolated rings of common bile duct and sphincter of Oddi

2002 ◽  
Vol 435 (1) ◽  
pp. 103-111 ◽  
Author(s):  
Janice Koepp ◽  
Alcı́bia M Cardozo ◽  
Pedro D'Orléans-Juste ◽  
Giles A Rae
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Guinea Pig ◽  
Sphincter Of Oddi ◽  
Endothelin 1

Effect of cisapride on the isolated guinea pig gall bladder and common bile duct

1997 ◽  
Vol 29 (5) ◽  
pp. 863-867 ◽  
Author(s):  
M. Koutsoviti-Papadopoulou ◽  
G. Kounenis ◽  
G. Batzias ◽  
V. Elezoglou
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Gall Bladder ◽  
Guinea Pig

Involvement of endogenous tachykinins and CGRP in the motor responses produced by capsaicin in the guinea-pig common bile duct

1999 ◽  
Vol 360 (3) ◽  
pp. 344-353 ◽  
Author(s):  
R. Patacchini ◽  
L. Barthó ◽  
R. De Giorgio ◽  
L. Lénárd Jr ◽  
V. Stanghellini ◽  
...  
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Guinea Pig ◽  
Motor Responses

scholarly journals Characterization of receptors mediating contraction induced by tachykinins in the guinea-pig isolated common bile duct

1997 ◽  
Vol 122 (8) ◽  
pp. 1633-1638 ◽  
Author(s):  
Riccardo Patacchini ◽  
Lorand Barthó ◽  
Carlo Alberto Maggi
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Guinea Pig

scholarly journals Effect of Morphine on the Mechanical Activity of Common Bile Duct Isolated from the Guinea Pig

1987 ◽  
Vol 66 (3) ◽  
pp. 245???248 ◽  
Author(s):  
Elik Vatashsky ◽  
Yuval Haskel ◽  
Shemuel Nissan ◽  
Menachem Hanani
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Guinea Pig ◽  
Mechanical Activity

Effects of cholecystokinin octapeptide on contractile motility of guinea pig common bile duct

1988 ◽  
Vol 254 (6) ◽  
pp. G819-G823
Author(s):  
T. Takahashi ◽  
M. Kusunoki ◽  
M. Kantoh ◽  
T. Yamamura ◽  
J. Utsunomiya
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Guinea Pig ◽  
Organ Bath ◽  
Dependent Manner ◽  
Ach Release ◽  
Phasic Contraction ◽  
Cholecystokinin Octapeptide ◽  
Superfusion System ◽  
Dose Dependent

Cholecystokinin octapeptide (CCK-8)-induced contraction and [3H]acetylcholine ([3H]-ACh) release from the longitudinal muscle strip of the guinea pig common bile duct were studied by a standard organ bath method and superfusion system. CCK-8 (10(-7) M) caused a biphasic contraction, a rapid phasic contraction followed by a fading tonic contraction. Hexamethonium, propranolol, and phentolamine had no effects on CCK-8-evoked contraction. Atropine or tetrodotoxin significantly reduced CCK-8-evoked initial phasic contraction and produced a rightward shift of the dose-response curve for CCK-8 (10(-10)-3 x 10(-7) M). CCK-8 provoked a significant [3H]ACh release in a dose-dependent manner, which was almost completely abolished by tetrodotoxin or Ca2+-free medium. These results suggest that CCK-8 receptors are present not only on the smooth muscle cells but also on the intramural cholinergic nerve cell bodies of the guinea pig common bile duct.

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