Sensitivity of glioma and fetal brain cell lines to natural killer cytolysis in a monolayer assay

1989 ◽  
Vol 7 (2) ◽  
pp. 145-152 ◽  
Author(s):  
Rene Myers Kazimer ◽  
Ronald L. Whisler ◽  
Ralph E. Stephens ◽  
Dennis K. Pearl ◽  
Allan J. Yates
Keyword(s):  
Natural Killer ◽  
Cell Lines ◽  
Fetal Brain ◽  
Brain Cell ◽  
Brain Cell Lines

Human Retinal and Brain Cell Lines: A Model of HCMV Retinitis and Encephalitis

2006 ◽  
Vol 25 (10) ◽  
pp. 581-596
Author(s):  
Kamla Dutt ◽  
Ifeoma Ezeonu
Keyword(s):  
Cell Lines ◽  
Brain Cell ◽  
Brain Cell Lines

Thy-1 antigen expression on rat brain cell lines

1978 ◽  
Vol 153 (1) ◽  
pp. 109-120 ◽  
Author(s):  
Jayne F. Lesley ◽  
Vanda A. Lennon
Keyword(s):  
Rat Brain ◽  
Cell Lines ◽  
Antigen Expression ◽  
Brain Cell ◽  
Brain Cell Lines

scholarly journals Directed establishment of rat brain cell lines with the phenotypic characteristics of type 1 astrocytes.

1992 ◽  
Vol 89 (14) ◽  
pp. 6467-6471 ◽  
Author(s):  
E. H. Radany ◽  
M. Brenner ◽  
F. Besnard ◽  
V. Bigornia ◽  
J. M. Bishop ◽  
...  
Keyword(s):  
Rat Brain ◽  
Cell Lines ◽  
Brain Cell ◽  
Phenotypic Characteristics ◽  
Brain Cell Lines

Metabolism of dehydroepiandrosterone by rodent brain cell lines: Relationship between 7-hydroxylation and aromatization

2005 ◽  
Vol 93 (1) ◽  
pp. 81-86 ◽  
Author(s):  
Peter H. Jellinck ◽  
Gist Croft ◽  
Bruce S. McEwen ◽  
Andres Gottfried-Blackmore ◽  
Glenville Jones ◽  
...  
Keyword(s):  
Cell Lines ◽  
Brain Cell ◽  
Rodent Brain ◽  
Brain Cell Lines

Biochemical analysis of selenoprotein expression in brain cell lines and in distinct brain regions

2008 ◽  
Vol 332 (3) ◽  
pp. 403-414 ◽  
Author(s):  
Barbara Hoppe ◽  
Anja U. Bräuer ◽  
Markus Kühbacher ◽  
Nicolai E. Savaskan ◽  
Dietrich Behne ◽  
...  
Keyword(s):  
Cell Lines ◽  
Biochemical Analysis ◽  
Brain Regions ◽  
Brain Cell ◽  
Brain Cell Lines

Establishment of human embryonic brain cell lines

2001 ◽  
Vol 37 (5) ◽  
pp. 259-262 ◽  
Author(s):  
Bipin Kumar ◽  
Alicia R. Hovland ◽  
Judith E. Prasad ◽  
Edward Clarkson ◽  
William C. Cole ◽  
...  
Keyword(s):  
Cell Lines ◽  
Brain Cell ◽  
Embryonic Brain ◽  
Brain Cell Lines

scholarly journals The Effect of the Classical TSPO Ligand PK 11195 On in Vitro Cobalt Chloride Model of Hypoxia in Non-Neuronal and Brain Cell Lines

2021 ◽  
Author(s):  
Rula Amara ◽  
Nidal Zeineh ◽  
Sheelu Monga ◽  
Abraham Weisman ◽  
Moshe Gavish
Keyword(s):  
Membrane Potential ◽  
Mitochondrial Membrane Potential ◽  
Cell Lines ◽  
Mitochondrial Membrane ◽  
Brain Cell ◽  
Cellular Damage ◽  
Brain Diseases ◽  
Dependent Manner ◽  
Brain Cell Lines

Abstract The mitochondrial translocator protein (TSPO) is a modulator of the apoptotic pathway involving reactive oxygen species (ROS) generation, mitochondrial membrane potential (Δψm) collapse, activation of caspases and eventually initiation of the apoptotic process. In this in vitro study, H1299 lung cells and BV-2 microglial cells were exposed to the hypoxic effect of CoCl2 with or without PK 11195. Exposing the H1299 cells to 0.5 mM CoCl2 for 24 hours resulted in decreases in cell viability (63%, p<0.05), elevation of cardiolipin peroxidation levels (38%, p<0.05), mitochondrial membrane potential depolarization (13%, p<0.001), and apoptotic cell death (117%, p<0.05). Pretreatment with PK 11195 (25 µM) exhibited significant protective capacity on CoCl2-induced alterations in the mentioned processes. Exposure of BV-2 cells to increasing concentrations of CoCl2 (0.3, 0.5, 0.7 mM) for 4 hours resulted in alterations in the same cellular processes. These alterations were obtained in a dose-dependent manner, except the changes in caspases 3 and 9. The novel ligands as well as PK 1195 attenuated the in vitro hypoxic effects of CoCl2.It appears that the TSPO ligand PK 11195 can prevent CoCl2-induced cellular damage in both non-neuronal and brain cell lines, and they may offer new therapeutic options in hypoxia-related lung and brain diseases which fail to respond to conventional therapies.

ESTABLISHMENT OF HUMAN EMBRYONIC BRAIN CELL LINES

2001 ◽  
Vol 37 (5) ◽  
pp. 259 ◽  
Author(s):  
BIPIN KUMAR ◽  
ALICIA R. HOVLAND ◽  
JUDITH E. PRASAD ◽  
EDWARD CLARKSON ◽  
WILLIAM C. COLE ◽  
...  
Keyword(s):  
Cell Lines ◽  
Brain Cell ◽  
Embryonic Brain ◽  
Brain Cell Lines

scholarly journals Neuroligin affects metastatic performance of CD66+ cells: Theoretical analysis of Multi-tissue RNA expressions through System modeling based Network mapping under in-vitro constraints

2020 ◽  
Author(s):  
Om Prakash
Keyword(s):  
Theoretical Analysis ◽  
Cell Lines ◽  
System Modeling ◽  
Brain Cell ◽  
System Model ◽  
Human Female ◽  
Metastatic Behavior ◽  
Network Mapping ◽  
Brain Cell Lines

ABSTRACTPresent study deals with theoretical analysis of multi-tissue RNA expressions through system model based network mapping under the constraints of in-vitro experiments. Here, effect of Neuroligin was evaluated on the performance of metastatic behavior of CD66+ cells of human female reproductive cell lines. Total 10 genes and 14 cell lines were considered in the study. Clustering of cell lines was done on the basis of network mapping under the same homeostatic constraints. Neuroligin was found to affect metastatic performance of CD66+ cells. Two CD66+ cell lines hTERT-HME1 and SK-BR-3 were found to most effective, in similar manner as brain cell lines as U-138MG & U-87MG.

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