Morphology of donor lens-capsule material studied by SEM

1990 ◽  
Vol 75 (3-4) ◽  
pp. 343-350 ◽  
Author(s):  
W. L. Jongebloed ◽  
L. I. Los ◽  
F. Dijk ◽  
J. G. F. Worst
Keyword(s):  
Lens Capsule ◽  
Capsule Material

Lens-capsule material of human and animal origin, studied by SEM

1989 ◽  
Vol 72 (3-4) ◽  
pp. 357-365 ◽  
Author(s):  
L. I. Los ◽  
W. L. Jongebloed ◽  
J. G. F. Worst
Keyword(s):  
Lens Capsule ◽  
Animal Origin ◽  
Capsule Material

Human and rabbit lens capsule material examined by SEM

1989 ◽  
Vol 31 (4) ◽  
pp. 469
Author(s):  
W.L. Jongebloed ◽  
L. Los ◽  
F. Dijk ◽  
J.G.F. Worst
Keyword(s):  
Lens Capsule ◽  
Rabbit Lens ◽  
Capsule Material

scholarly journals P 229 Growth of human lens epithelial cells on the anterior lens capsule in vitro

1995 ◽  
Vol 35 ◽  
pp. S199
Author(s):  
J.H. Meyer ◽  
J. Schmidt ◽  
F. Eppinger ◽  
B. Flügel ◽  
K.U. Löffler ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Lens Capsule ◽  
Human Lens ◽  
Lens Epithelial Cells ◽  
Human Lens Epithelial Cells ◽  
Anterior Lens Capsule

scholarly journals Nanogel-Facilitated In-Situ Delivery of a Cataract Inhibitor

Biomolecules ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1150
Author(s):  
Dixa Gautam ◽  
Michelle G. Pedler ◽  
Devatha P. Nair ◽  
Jonathan Mark Petrash
Keyword(s):  
Cataract Surgery ◽  
Vision Loss ◽  
Effective Means ◽  
Lens Capsule ◽  
Posterior Capsular Opacification ◽  
Surgical Removal ◽  
Visual Disability ◽  
Visual Axis ◽  
Number Of Patients ◽  
Subsequent Degradation

Cataracts are a leading cause of blindness worldwide. Surgical removal of cataracts is a safe and effective procedure to restore vision. However, a large number of patients later develop vision loss due to regrowth of lens cells and subsequent degradation of the visual axis leading to visual disability. This postsurgical complication, known as posterior capsular opacification (PCO), occurs in up to 30% of cataract patients and has no clinically proven pharmacological means of prevention. Despite the availability of many compounds capable of preventing early steps in PCO development, there is currently no effective means to deliver such therapies into the eye for a suitable duration. To model a solution to this unmet medical need, we fabricated acrylic substrates as intraocular lens (IOL) mimics scaled to place into the capsular bag of the mouse lens following a mock-cataract surgery. Substrates were coated with a hydrophilic crosslinked acrylate nanogel designed to elute Sorbinil, an aldose reductase inhibitor previously shown to suppress PCO. Insertion of the Sorbinil-eluting device into the lens capsule at the time of cataract surgery resulted in substantial prevention of cellular changes associated with PCO development. This model demonstrates that a cataract inhibitor can be delivered into the postsurgical lens capsule at therapeutic levels.

Development and properties of zein/ Tremella fuciformis polysaccharides blend as a hard capsule material

2021 ◽  
pp. 51379
Author(s):  
Lanying Tian ◽  
Hongxiu Fan ◽  
Hongcheng Liu ◽  
Zhengquan Tong ◽  
Tingting Liu ◽  
...  
Keyword(s):  
Tremella Fuciformis ◽  
Capsule Material

scholarly journals Regional mechanical properties and stress analysis of the human anterior lens capsule

2007 ◽  
Vol 47 (13) ◽  
pp. 1781-1789 ◽  
Author(s):  
R.M. Pedrigi ◽  
G. David ◽  
J. Dziezyc ◽  
J.D. Humphrey
Keyword(s):  
Mechanical Properties ◽  
Stress Analysis ◽  
Lens Capsule ◽  
Anterior Lens Capsule

An immunoelectron microscope study of the aged human lens capsule

1992 ◽  
Vol 54 (3) ◽  
pp. 393-401 ◽  
Author(s):  
George E. Marshall ◽  
Anastasios G.P. Konstas ◽  
Nikolaos E. Bechrakis ◽  
William R. Lee
Keyword(s):  
Microscope Study ◽  
Lens Capsule ◽  
Human Lens
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