The influence of hypotonic treatment on the morphology of meiotic stages II. Prophase of the first meiotic division of female mice up to dictyotene

Genetica ◽  
1986 ◽  
Vol 70 (3) ◽  
pp. 161-165 ◽  
Author(s):  
A. J. J. Dietrich
Keyword(s):  
Meiotic Division ◽  
Female Mice ◽  
Hypotonic Treatment

scholarly journals Effect of sperm genotype on chromatid segregation in female mice heterozygous for aberrant chromosome 1

1993 ◽  
Vol 61 (2) ◽  
pp. 97-100 ◽  
Author(s):  
Sergei I. Agulnik ◽  
Igor D. Sabantsev ◽  
Anatoly O. Ruvinsky
Keyword(s):  
Experimental Data ◽  
Mus Musculus ◽  
Meiotic Division ◽  
Chromosome 1 ◽  
Wild Populations ◽  
Aberrant Chromosome ◽  
Female Mice ◽  
Mus Musculus Musculus ◽  
Chromatid Segregation ◽  
Extra Segment

SummaryAn aberrant chromosome 1 with two large homogeneously staining insertions was isolated from wild populations of Mus musculus musculus. The specific features of the aberrant chromosome have been described elsewhere (Agulnik et al. 1990). These include its preferential entry into the oocyte of heterozygous females, increased mortality of homozygotes and decreased fertility of homozygous females. Here we present data indicating that chromatid segregation in heterozygous females depends upon which sperm enters the oocyte before the second meiotic division: meioticdrive is powerful when it is sperm bearing normal chromosome 1, and segregation normalizesduring Mil when it is sperm bearing chromosome 1 with the extra segment. Experimental data are adduced and explanations offered for the observed phenomenon.

scholarly journals The influence of mutations on chromosome 17 upon the segregation of homologues in female mice heterozygous for Robertsonian translocations

1987 ◽  
Vol 50 (3) ◽  
pp. 235-237 ◽  
Author(s):  
A. O. Ruvinsky ◽  
S. I. Agulnik ◽  
A. I. Agulnik ◽  
D. K. Belyaev
Keyword(s):  
Genetic Analysis ◽  
Segregation Distortion ◽  
Meiotic Division ◽  
Polar Body ◽  
Normal Karyotype ◽  
Metacentric Chromosome ◽  
Chromosome 17 ◽  
Robertsonian Translocations ◽  
Female Mice ◽  
Female Genotype

SummaryThe influence of mutations in chromosome 17 upon the segregation of the metacentric and acrocentric homologues in the progeny of female mice heterozygous for Robertsonian translocations Rb(8.17)11em and Rb(16.17)7Bnr was studied. Genetic analysis indicated that the portion of non-Rb (normal karyotype) progeny from mothers heterozygous for mutations tf, qk, t12 was weakly different from the 50% Mendelian expected level (55–57%). Introduction of mutations T, FuKi, Fu, t6 into the female genotype caused a stronger segregation distortion and an increase in the portion of progeny with normal karyotype (63–67%). From the data on embryonic mortality and cytogenetic observations it is concluded that a distortion of equal transmission arises before M II of meiosis. Consequently, the preferential distribution of the metacentric chromosome to the polar body during the first meiotic division is relevant to the observed segregation distortion.

Central forebrain Fos responses to familiar male odours are attenuated in recently mated female mice

2001 ◽  
Vol 13 (2) ◽  
pp. 389-399 ◽  
Author(s):  
Heather A. Halem ◽  
James A. Cherry ◽  
Michael J. Baum
Keyword(s):  
Female Mice ◽  
Mated Female

A subchronic oral toxicity study on medical herb extract, KIOM CRC#BP10A, in male and female mice

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
ES Cho ◽  
YJ Lee ◽  
JS Park ◽  
J Kim ◽  
NS Kim ◽  
...  
Keyword(s):  
Toxicity Study ◽  
Oral Toxicity ◽  
Male And Female ◽  
Female Mice ◽  
Subchronic Oral Toxicity Study ◽  
Herb Extract

HUMAN URINARY GONADOTROPHINS ASSAYED BY DIFFERENT RESPONSES IN THE SAME ANIMAL

1960 ◽  
Vol XXXIV (III) ◽  
pp. 375-389 ◽  
Author(s):  
P. S. Brown
Keyword(s):  
Postmenopausal Women ◽  
Ovarian Response ◽  
The Other ◽  
Relative Potency ◽  
Vaginal Opening ◽  
Serial Sections ◽  
Immature Female ◽  
Female Mice ◽  
Marked Disparity ◽  
Relative Potencies

ABSTRACT Selected human urinary gonadotrophins were assayed against one another using various measures of response in the same immature female mice. Intact or hypophysectomized animals were used and in some experiments the results of hypophysectomy were checked in complete serial sections. Extracts from the urine of two subjects with Turner's syndrome were compared. In intact mice, the relative potency judged by the ovarian response differed from that shown by the uterine response and the 95 % fiducial limits of the two estimates did not overlap. When the mice were hypophysectomized, one extract became much less potent while the other did not. Similar differences were shown in the response of intact mice to urinary extracts from two subjects with Klinefelter's syndrome. There was a marked disparity between the relative potencies shown by the uterine response and by the incidence of vaginal opening. Similar differences were not shown between the responses to different extracts from the urine of normal postmenopausal women, but these extracts were known to differ little in quality. The results are interpreted in terms of qualitative differences between human urinary gonadotrophins.

Sign in / Sign up

Export Citation Format

Share Document