Beta-lactam antibiotics inhibit human in vitro granulopoiesis and proliferation of some other cell types

1986 ◽  
Vol 2 (4) ◽  
pp. 513-521 ◽  
Author(s):  
Klaus A. Neftel ◽  
Marianne R. M�ller ◽  
Urs Widmer ◽  
Ambros W. H�gin
Keyword(s):  
Cell Types ◽  
Beta Lactam ◽  
Beta Lactam Antibiotics

scholarly journals In-vitro activities of cefepime and other beta-lactam antibiotics against clinical isolates from a Colombian teaching hospital

1998 ◽  
Vol 42 (4) ◽  
pp. 550-552 ◽  
Author(s):  
S. Mattar ◽  
L. Sanchez ◽  
D. Perez ◽  
A. Arango ◽  
R. Parodi ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Clinical Isolates ◽  
Beta Lactam ◽  
Beta Lactam Antibiotics

scholarly journals Species-Specific Sensitivity of Coagulase-Negative Staphylococci to Single Antibiotics and Their Combinations

2011 ◽  
Vol 60 (2) ◽  
pp. 155-161 ◽  
Author(s):  
GRAŻYNA SZYMAŃSKA ◽  
MAGDALENA SZEMRAJ ◽  
ELIGIA M. SZEWCZYK
Keyword(s):  
University Hospital ◽  
Hospital Environment ◽  
Beta Lactam ◽  
Coagulase Negative Staphylococci ◽  
Methicillin Resistant ◽  
Beta Lactam Antibiotics ◽  
Resistant Strains ◽  
Staphylococcus Hominis ◽  
Species Specific

The activity of beta-lactam antibiotics (oxacillin, cloxacillin, cephalotin), vancomycin, gentamicin and rifampicin applied in vitro individually and in combination against 37 nosocomial methicillin-resistant strains of coagulase-negative staphylococci (CNS) was assessed to demonstrate the heterogeneity of this group of bacteria and estimate the chance of the efficacy of such therapy. The strains belonged to four species: Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus cohnii, Staphylococcus hominis. They originated from a hospital environment and from the skin of medical staff of the intensive care unit of a paediatric ward at a university hospital. All strains were methicillin-resistant, according to CLSI standards, but individual strains differed in MIC(ox) values. Susceptibility to other tested antibiotics was also characteristic for the species. The increased susceptibility to antibiotics in combinations, tested by calculating the fractional inhibitory concentration (FIC) index, concerned 26 out of 37 investigated strains and it was a feature of a particular species. Combinations of vancomycin and cephalotin against S. epidermidis and oxacillin with vancomycin were significant, as well as cephalotin and rifampicin in growth inhibition of multiresistant S. haemolyticus strains.

Comparative in vitro activity of sisomicin and its interactions with beta-lactam antibiotics

Infection ◽  
1979 ◽  
Vol 7 (S3) ◽  
pp. S246-S246
Author(s):  
H. Gaya ◽  
E. M. Brown ◽  
P. Friedman ◽  
S. E. M. Cox
Keyword(s):  
Vitro Activity ◽  
In Vitro Activity ◽  
Beta Lactam ◽  
Beta Lactam Antibiotics
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