Instructional leadership specifications for school executives: A preliminary validation study

1991 ◽  
Vol 5 (1) ◽  
pp. 21-30 ◽  
Author(s):  
Ben M. Harris ◽  
Lucy Wilson
Keyword(s):  
Instructional Leadership ◽  
Validation Study ◽  
Preliminary Validation ◽  
School Executives

Reference standards for gene fusion molecular assays on cytological samples: an international validation study

2021 ◽  
pp. jclinpath-2021-207825
Author(s):  
Umberto Malapelle ◽  
Francesco Pepe ◽  
Pasquale Pisapia ◽  
Annalisa Altimari ◽  
Claudio Bellevicine ◽  
...  
Keyword(s):  
Cell Line ◽  
Validation Study ◽  
Gene Fusion ◽  
Variant Calling ◽  
Reference Standards ◽  
Gene Fusions ◽  
Wild Type ◽  
Molecular Assays ◽  
Preliminary Validation ◽  
Pap Staining

AimsGene fusions assays are key for personalised treatments of advanced human cancers. Their implementation on cytological material requires a preliminary validation that may make use of cell line slides mimicking cytological samples. In this international multi-institutional study, gene fusion reference standards were developed and validated.MethodsCell lines harbouring EML4(13)–ALK(20) and SLC34A2(4)–ROS1(32) gene fusions were adopted to prepare reference standards. Eight laboratories (five adopting amplicon-based and three hybridisation-based platforms) received, at different dilution points two sets of slides (slide A 50.0%, slide B 25.0%, slide C 12.5% and slide D wild type) stained by Papanicolaou (Pap) and May Grunwald Giemsa (MGG). Analysis was carried out on a total of 64 slides.ResultsFour (50.0%) out of eight laboratories reported results on all slides and dilution points. While 12 (37.5%) out of 32 MGG slides were inadequate, 27 (84.4%) out of 32 Pap slides produced libraries adequate for variant calling. The laboratories using hybridisation-based platforms showed the highest rate of inadequate results (13/24 slides, 54.2%). Conversely, only 10.0% (4/40 slides) of inadequate results were reported by laboratories adopting amplicon-based platforms.ConclusionsReference standards in cytological format yield better results when Pap staining and processed by amplicon-based assays. Further investigation is required to optimise these standards for MGG stained cells and for hybridisation-based approaches.

scholarly journals A Preliminary Validation Study of Diffusion Tensor Imaging as a Measure of Functional Brain Injury

2008 ◽  
Vol 65 (9) ◽  
Author(s):  
Robert J. Fox ◽  
Roderick W. McColl ◽  
Jar-Chi Lee ◽  
Teresa Frohman ◽  
Ken Sakaie ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Brain Injury ◽  
Validation Study ◽  
Diffusion Tensor ◽  
Functional Brain ◽  
Preliminary Validation

scholarly journals Virtual reality simulation to teach videolaryngoscopy: a preliminary validation study

2020 ◽  
Vol 125 (1) ◽  
pp. e209-e210
Author(s):  
P. Schoettker ◽  
A. Potié ◽  
A. Dzyuba ◽  
E. Ovcharenko ◽  
N. De Wydt ◽  
...  
Keyword(s):  
Virtual Reality ◽  
Validation Study ◽  
Virtual Reality Simulation ◽  
Preliminary Validation

scholarly journals 1055 A Preliminary Validation Study of a Composite Sleep Health Index: Associations with Psychological Distress, Obesity, and Physical Functioning

SLEEP ◽  
2018 ◽  
Vol 41 (suppl_1) ◽  
pp. A392-A393
Author(s):  
W M Troxel ◽  
A DeSantis ◽  
B Ghosh-Dastidar ◽  
G Hunter ◽  
D Buysse ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Validation Study ◽  
Physical Functioning ◽  
Health Index ◽  
Sleep Health ◽  
Preliminary Validation

scholarly journals An Integrated System for 3D Hip Joint Reconstruction from 2D X-rays: A Preliminary Validation Study

2013 ◽  
Vol 41 (10) ◽  
pp. 2077-2087 ◽  
Author(s):  
Steffen Schumann ◽  
Li Liu ◽  
Moritz Tannast ◽  
Mathias Bergmann ◽  
Lutz-P. Nolte ◽  
...  
Keyword(s):  
Hip Joint ◽  
Validation Study ◽  
Integrated System ◽  
X Rays ◽  
Joint Reconstruction ◽  
Preliminary Validation
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