On sequential procedures for the point estimation of the mean of a normal population

1988 ◽  
Vol 40 (4) ◽  
pp. 769-783 ◽  
Author(s):  
Ajit Chaturvedi
Keyword(s):  
Normal Population ◽  
Point Estimation ◽  
Sequential Procedures ◽  
The Mean

On Sequential Procedures for the Point Estimation of the Mean Vector

1988 ◽  
Vol 37 (1-2) ◽  
pp. 47-54 ◽  
Author(s):  
R. Karan Singh ◽  
Ajit Chaturvedi
Keyword(s):  
Normal Population ◽  
Stopping Time ◽  
Point Estimation ◽  
Multivariate Normal ◽  
Minimum Risk ◽  
Sequential Procedures ◽  
Multivariate Normal Population ◽  
Bounded Risk ◽  
The Mean ◽  
Mean Vector

Sequential procedures are proposed for (a) the minimum risk point estimation and (b) the bounded risk point estimation of the mean vector of a multivariate normal population . Second-order approximations are derived. For the problem (b), a lower bound for the number of additional observations (after stopping time) is obtained which ensures “ exact” boundedness of the risk associated witb the sequential procedure.

Detection of Circulating Tissue Factor and Factor VII in a Normal Population

1996 ◽  
Vol 75 (05) ◽  
pp. 772-777 ◽  
Author(s):  
Sybille Albrecht ◽  
Matthias Kotzsch ◽  
Gabriele Siegert ◽  
Thomas Luther ◽  
Heinz Großmann ◽  
...  
Keyword(s):  
Tissue Factor ◽  
Normal Population ◽  
Mean Value ◽  
Factor Vii ◽  
Significant Difference ◽  
Age Dependent ◽  
The Mean ◽  
Highly Correlated ◽  
And Gender

SummaryThe plasma tissue factor (TF) concentration was correlated to factor VII concentration (FVIIag) and factor VII activity (FVIIc) in 498 healthy volunteers ranging in age from 17 to 64 years. Immunoassays using monoclonal antibodies (mAbs) were developed for the determination of TF and FVIIag in plasma. The mAbs and the test systems were characterized. The mean value of the TF concentration was 172 ± 135 pg/ml. TF showed no age- and gender-related differences. For the total population, FVIIc, determined by a clotting test, was 110 ± 15% and the factor VIlag was 0.77 ± 0.19 μg/ml. FVII activity was significantly increased with age, whereas the concentration demonstrated no correlation to age in this population. FVII concentration is highly correlated with the activity as measured by clotting assay using rabbit thromboplastin. The ratio between FVIIc and FVIIag was not age-dependent, but demonstrated a significant difference between men and women. Between TF and FVII we could not detect a correlation.

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