Antitumor activity of edible marine algae: Effect of crude fucoidan fractions prepared from edible brown seaweeds against L-1210 leukemia

Hydrobiologia ◽  
1984 ◽  
Vol 116-117 (1) ◽  
pp. 145-148 ◽  
Author(s):  
I. Yamamoto ◽  
M. Takahashi ◽  
E. Tamura ◽  
H. Maruyama ◽  
H. Mori
Author(s):  
Hiroyuki Noda ◽  
Hideomi Amano ◽  
Koichi Arashima ◽  
Kazutosi Nisizawa

1981 ◽  
Vol 4 (12) ◽  
pp. 928-932 ◽  
Author(s):  
MOTOKO INOMATA ◽  
FUMIKO FUKUOKA ◽  
AKIO HOSHI ◽  
KAZUO KURETANI ◽  
MINEO SANEYOSHI

2017 ◽  
Vol 22 (4) ◽  
pp. 371 ◽  
Author(s):  
Bui Minh Ly ◽  
Ngo Quoc Buu ◽  
Nguyen Duy Nhut ◽  
Pham Duc Thinh ◽  
Tran Thi Thanh Van

Sulfated fucans are among the most widely studied of all the sulfated polysaccharides of plant origin that exhibit biological activities in mammalian systems. In this report fucoidans from some Vietnamese Sargassumspecies such as S.polycystum, S.oligocystum, S.mcclurei, S. Swartzii and denticaprum were extracted and fractionated on a DEAE-Sephadex A-25 column. On the basis of chemical and spectral analyses, the fucoidan fractions obtained were found to be the sulfated fucogalactans containing sulfate ester groups and uronic acid, and composed essentially of fucose and galactose, as well as a minor amount of other sugars. The polysaccharide fractions were tested for anticancer activity. The primarily obtained results showed that all fucoidan fractions isolated from S. swartziidemonstrate bioactivity effects against cancer cells, while fraction F5 with a highest sulfate content exhibits the strongest anti-invasion activity. This indicates that sulfate content plays an important role in the anticancer activity of the brown algal fucoidans. A laboratory scale pilot for fuco idan production from Vietnamese brown seaweeds has been set with a capacity of 500 g of crude fucoidan per day. 


2020 ◽  
Vol 16 ◽  
Author(s):  
Saidani Karima ◽  
Ziani Nadia ◽  
Touati Naima ◽  
Merzouk Hafida ◽  
Bedjou Fatiha

: The aim of this study was to evaluate the anticoagulant activity of five marine algae from Bejaia’s coast (Algeria). Higher contents of phenolic compounds were obtained with ethanol for Cystoseira humilis, Halopteris scoparia, Padina pavonica and Rhodomela confervoides (8.55±0.29, 7.84±0.47, 6.41±0.14 and 4.16±0.04 mg CE/g of dw, respectively). Whereas, for Sargassum vulgare, the extraction with acetone showed higher content (3.04±0.071 mg CE/g of dw).The determination of sugar content showed that acetone extract of the five seaweeds was the richest in sugar, this rate increasingly dropped in ethanol extract and the fractions A and B. The red algae Rhodomela confervoides showed a significant anticoagulant activity in ethanol extract and the fractions A, B and C, with an elongation up to 407.97±58.12 s in the fraction C, at a concentration of 10 mg/mL. An anticoagulant activity was observed in the fractions A, B and C of all the brown seaweeds. A procoagulant activity was observed in the fractions A, B of Cystoseira humilis and Sargassum vulgare as well as the fraction B of Padina pavonica with an indeterminate period, at 10 mg/mL.


Hydrobiologia ◽  
1990 ◽  
Vol 204-205 (1) ◽  
pp. 577-584 ◽  
Author(s):  
Hiroyuki Noda ◽  
Hideomi Amano ◽  
Koichi Arashima ◽  
Kazutosi Nisizawa

1997 ◽  
Vol 20 (5) ◽  
pp. 541-546 ◽  
Author(s):  
Hideki HARADA ◽  
Tadahide NORO ◽  
Yuto KAMEI

1998 ◽  
Vol 64 (5) ◽  
pp. 847-853 ◽  
Author(s):  
Yukihiro Osumi ◽  
Masanobu Kawai ◽  
Hideomi Amano ◽  
Hiroyuki Noda

2021 ◽  
Vol 68 (3) ◽  
pp. 175-247
Author(s):  
Rachel Einav ◽  
Michael D. Guiry ◽  
Álvaro Israel

Abstract A taxonomic list of macro marine algae (seaweeds) described in the literature for the Red Sea during the years 1756–2020 is presented. The list was prepared using existing published studies, local monitoring reports, as well as “grey” or unpublished lists of seaweeds for the area. Altogether, we examined more than 300 publications and compiled more than 900 taxonomic names, of which 576 correspond to valid species, whilst 355 names were considered synonyms for these species. The phylum Chlorophyta (green seaweeds) was represented by 37 currently accepted genera and 133 species (including 74 species synonyms). The phylum Ochrophyta (Phaeophyceae only; brown seaweeds) was represented by 52 genera, 157 species and 99 synonyms; and the phylum Rhodophyta (red seaweeds) by 130 genera, 286 species and 182 synonyms. The brown seaweed Sargassum appears to be a particularly biodiverse genus in the area represented by 58 species and 26 synonyms. Our study shows the inconsistency and lack of long-term taxonomic studies and recent molecular investigations of seaweeds from nearly the whole Red Sea.


1966 ◽  
Vol 44 (2) ◽  
pp. 209-218 ◽  
Author(s):  
Gordon F. Townsend ◽  
Norma Baxter ◽  
William H. Brown ◽  
Ethel E. Felauer

Antitumor activity has been demonstrated against Ehrlich, L.1210 leukemia, and to a less extent against TA3 mammary carcinoma ascites cells by a group of short chain fatty acids. Activity is confined to the finely suspended ester forms of the acids and seems to be associated with the carboxyl end of the molecule. The compounds appear to have no effect upon the production of normal white blood cells.


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