Triticum aestivum puroindolines, two basic cystine-rich seed proteins: cDNA sequence analysis and developmental gene expression

1994 ◽  
Vol 25 (1) ◽  
pp. 43-57 ◽  
Author(s):  
Marie-Fran�oise Gautier ◽  
Marie-Elisabeth Aleman ◽  
Anne Guirao ◽  
Didier Marion ◽  
Philippe Joudrier
Keyword(s):  
Gene Expression ◽  
Triticum Aestivum ◽  
Sequence Analysis ◽  
Cdna Sequence ◽  
Seed Proteins ◽  
Developmental Gene ◽  
Developmental Gene Expression ◽  
Cdna Sequence Analysis

scholarly journals Correction: RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression

PLoS ONE ◽  
2016 ◽  
Vol 11 (7) ◽  
pp. e0160295 ◽  
Author(s):  
Adam Labadorf ◽  
Andrew G. Hoss ◽  
Valentina Lagomarsino ◽  
Jeanne C. Latourelle ◽  
Tiffany C. Hadzi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Sequence Analysis ◽  
Huntington Disease ◽  
Developmental Gene ◽  
Rna Sequence ◽  
Developmental Gene Expression

scholarly journals RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression

PLoS ONE ◽  
2015 ◽  
Vol 10 (12) ◽  
pp. e0143563 ◽  
Author(s):  
Adam Labadorf ◽  
Andrew G. Hoss ◽  
Valentina Lagomarsino ◽  
Jeanne C. Latourelle ◽  
Tiffany C. Hadzi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Sequence Analysis ◽  
Huntington Disease ◽  
Developmental Gene ◽  
Rna Sequence ◽  
Developmental Gene Expression

scholarly journals Maternal Style Selectively Shapes Amygdalar Development and Social Behavior in Rats Genetically Prone to High Anxiety

2015 ◽  
Vol 37 (3) ◽  
pp. 203-214 ◽  
Author(s):  
Joshua L. Cohen ◽  
Matthew E. Glover ◽  
Phyllis C. Pugh ◽  
Andrew D. Fant ◽  
Rebecca K. Simmons ◽  
...  
Keyword(s):  
Gene Expression ◽  
Psychological Health ◽  
Early Life ◽  
Developmental Trajectory ◽  
Emotional Behavior ◽  
Developmental Gene ◽  
Developmental Gene Expression ◽  
Maternal Style ◽  
Anxiety Depression ◽  
Cross Fostering

The early-life environment critically influences neurodevelopment and later psychological health. To elucidate neural and environmental elements that shape emotional behavior, we developed a rat model of individual differences in temperament and environmental reactivity. We selectively bred rats for high versus low behavioral response to novelty and found that high-reactive (bred high-responder, bHR) rats displayed greater risk-taking, impulsivity and aggression relative to low-reactive (bred low-responder, bLR) rats, which showed high levels of anxiety/depression-like behavior and certain stress vulnerability. The bHR/bLR traits are heritable, but prior work revealed bHR/bLR maternal style differences, with bLR dams showing more maternal attention than bHRs. The present study implemented a cross-fostering paradigm to examine the contribution of maternal behavior to the brain development and emotional behavior of bLR offspring. bLR offspring were reared by biological bLR mothers or fostered to a bLR or bHR mother and then evaluated to determine the effects on the following: (1) developmental gene expression in the hippocampus and amygdala and (2) adult anxiety/depression-like behavior. Genome-wide expression profiling showed that cross-fostering bLR rats to bHR mothers shifted developmental gene expression in the amygdala (but not hippocampus), reduced adult anxiety and enhanced social interaction. Our findings illustrate how an early-life manipulation such as cross-fostering changes the brain's developmental trajectory and ultimately impacts adult behavior. Moreover, while earlier studies highlighted hippocampal differences contributing to the bHR/bLR phenotypes, our results point to a role of the amygdala as well. Future work will pursue genetic and cellular mechanisms within the amygdala that contribute to bHR/bLR behavior either at baseline or following environmental manipulations.

Sign in / Sign up

Export Citation Format

Share Document