Chemical Signalling in Beetles

2004 ◽  
pp. 85-166 ◽  
Author(s):  
Wittko Francke ◽  
Konrad Dettner
Keyword(s):  
Chemical Signalling

scholarly journals Bio-Guided Isolation of Antimalarial Metabolites from the Coculture of Two Red Sea Sponge-Derived Actinokineospora and Rhodococcus spp.

Marine Drugs ◽  
2021 ◽  
Vol 19 (2) ◽  
pp. 109
Author(s):  
Hani A. Alhadrami ◽  
Bathini Thissera ◽  
Marwa H. A. Hassan ◽  
Fathy A. Behery ◽  
Che Julius Ngwa ◽  
...  
Keyword(s):  
Red Sea ◽  
Antimalarial Activity ◽  
Axenic Culture ◽  
Trna Synthetase ◽  
Structural Motif ◽  
Natural Habitats ◽  
Signalling Molecules ◽  
Chemical Signalling ◽  
Axenic Conditions

Coculture is a productive technique to trigger microbes’ biosynthetic capacity by mimicking the natural habitats’ features principally by competition for food and space and interspecies cross-talks. Mixed cultivation of two Red Sea-derived actinobacteria, Actinokineospora spheciospongiae strain EG49 and Rhodococcus sp. UR59, resulted in the induction of several non-traced metabolites in their axenic cultures, which were detected using LC–HRMS metabolomics analysis. Antimalarial guided isolation of the cocultured fermentation led to the isolation of the angucyclines actinosporins E (1), H (2), G (3), tetragulol (5) and the anthraquinone capillasterquinone B (6), which were not reported under axenic conditions. Interestingly, actinosporins were previously induced when the axenic culture of the Actinokineospora spheciospongiae strain EG49 was treated with signalling molecule N-acetyl-d-glucosamine (GluNAc); this finding confirmed the effectiveness of coculture in the discovery of microbial metabolites yet to be discovered in the axenic fermentation with the potential that could be comparable to adding chemical signalling molecules in the fermentation flask. The isolated angucycline and anthraquinone compounds exhibited in vitro antimalarial activity and good biding affinity against lysyl-tRNA synthetase (PfKRS1), highlighting their potential developability as new antimalarial structural motif.

scholarly journals Cell fate clusters in ICM organoids arise from cell fate heredity and division: a modelling approach

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Tim Liebisch ◽  
Armin Drusko ◽  
Biena Mathew ◽  
Ernst H. K. Stelzer ◽  
Sabine C. Fischer ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Cell Division ◽  
Cell Fate ◽  
Inner Cell Mass ◽  
Cell Mass ◽  
Cell Lineage ◽  
Cell Fate Decision ◽  
Cell Fate Decisions ◽  
Chemical Signalling ◽  
Fate Decision

AbstractDuring the mammalian preimplantation phase, cells undergo two subsequent cell fate decisions. During the first decision, the trophectoderm and the inner cell mass are formed. Subsequently, the inner cell mass segregates into the epiblast and the primitive endoderm. Inner cell mass organoids represent an experimental model system, mimicking the second cell fate decision. It has been shown that cells of the same fate tend to cluster stronger than expected for random cell fate decisions. Three major processes are hypothesised to contribute to the cell fate arrangements: (1) chemical signalling; (2) cell sorting; and (3) cell proliferation. In order to quantify the influence of cell proliferation on the observed cell lineage type clustering, we developed an agent-based model accounting for mechanical cell–cell interaction, i.e. adhesion and repulsion, cell division, stochastic cell fate decision and cell fate heredity. The model supports the hypothesis that initial cell fate acquisition is a stochastically driven process, taking place in the early development of inner cell mass organoids. Further, we show that the observed neighbourhood structures can emerge solely due to cell fate heredity during cell division.

Male Chemical Signalling to Recruit Females in the Greater Short-Nosed Fruit Bat Cynopterus sphinx

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Anbalagan Rathinakumar ◽  
Murugavel Baheerathan ◽  
Barbara A. Caspers ◽  
Joseph J. Erinjery ◽  
Perumalswamy Kaliraj ◽  
...  
Keyword(s):  
Fruit Bat ◽  
Chemical Signalling ◽  
Cynopterus Sphinx

Chemical Signalling in Brown Bears

2019 ◽  
pp. 163-176
Author(s):  
Melanie Clapham ◽  
Owen T. Nevin ◽  
Ian Convery
Keyword(s):  
Brown Bears ◽  
Chemical Signalling

Bacterial Action and Chemical Signalling in the Red Fox(Vulpes vulpes)and Other Mammals

1978 ◽  
pp. 78-91 ◽  
Author(s):  
ERIC S. ALBONE ◽  
PAULINE E. GOSDEN ◽  
GEORGES C. WARE ◽  
DAVID W. MACDONALD ◽  
NICHOLAS G. HOUGH
Keyword(s):  
Vulpes Vulpes ◽  
Red Fox ◽  
Chemical Signalling ◽  
Bacterial Action

Perceived dominance status affects chemical signalling in the neriid fly Telostylinus angusticollis

2019 ◽  
Vol 158 ◽  
pp. 161-174
Author(s):  
Zachariah Wylde ◽  
Lewis Adler ◽  
Angela Crean ◽  
Russell Bonduriansky
Keyword(s):  
Dominance Status ◽  
Chemical Signalling

Studies on hexactinellid sponges. II. Excitability, conduction and coordination of responses in rhabdocalyptus dawsoni (lambe, 1873)

1983 ◽  
Vol 301 (1107) ◽  
pp. 401-418 ◽  
Keyword(s):  
Electrical Stimulation ◽  
Refractory Period ◽  
Conduction System ◽  
Conduction Time ◽  
Pumping Power ◽  
Chemical Signalling ◽  
Conduction Pathway ◽  
Electrical Impulses ◽  
Effector Response ◽  
Hexactinellid Sponges

Rhabdocalyptus can arrest its feeding current. The response is initiated by mechanical or electrical stimulation, and is coordinated through the sponge by a conduction system, having a precise excitability threshold and conducting on an all-or-none basis. All parts are excitable and conduct. Individuals in colonial assemblages are coordinated. Spontaneous as well as evoked arrests are observed. There is evidence of scattered pacemaker sites. Conduction is diffuse and unpolarized, and occurs with a velocity of 0.26 ± 0.07 cm s -1 at 11 °C. The conduction system is probably the trabecular syncytium. Isolated dermal membrane (‘pure’ trabecular tissue, without flagella or contractile elements) conducts. Mechanical and chemical signalling mechanisms are discussed. It is concluded that they cannot account for the phenomena observed, but that conduction must involve electrical impulses. The effectors responsible for current arrests are almost certainly the flagella of the flagellated chambers. It is assumed that they stop beating on receiving an arrest signal through the conduction pathway. The waveforms of arrests recorded with a thermistor flowmeter are best interpreted in terms of sudden, all-or-none cessation of pumping, with slow, gradual recovery of full pumping power. The flagella probably beat feebly at first on becoming active again following an arrest. The effector response shows a refractory period of 30 s. Responses occur with short latency. Delays are attributable to conduction time. The system is fatigueable. Numerous parallels exist with the behaviour of the stigmatal cilia in the ascidian branchial sac, both in the characteristics of the effector response and in the mechanism of coordination.

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