scholarly journals Pearson Syndrome: A Retrospective Cohort Study from the Marrow Failure Study Group of A.I.E.O.P. (Associazione Italiana Emato-Oncologia Pediatrica)

2015 ◽  
pp. 37-43 ◽  
Author(s):  
Piero Farruggia ◽  
Andrea Di Cataldo ◽  
Rita M. Pinto ◽  
Elena Palmisani ◽  
Alessandra Macaluso ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Study Group ◽  
Pearson Syndrome

scholarly journals Clomiphene Citrate Priming Increases Sensitivity During Ovarian Stimulation in Poor Ovarian Responders Undergoing In Vitro Fertilization Treatment: A Retrospective Cohort Study

2021 ◽  
Author(s):  
Shan Liu ◽  
Xinyu Liu ◽  
Huanhuan Li ◽  
Minghui Liu ◽  
Yasu Lv ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Ovarian Stimulation ◽  
Retrospective Cohort ◽  
Clomiphene Citrate ◽  
Control Group ◽  
Study Group ◽  
Poor Ovarian Responders ◽  
Gonadotropin Dosage ◽  
Antagonist Protocol

Abstract Background: Since ovarian stimulation was introduced as an assisted reproductive technology, poor ovarian response (POR) management has challenged clinicians. Guidance on optimally managing patients with poor response and/or low sensitivity to ovarian stimulation is still lacking. We aimed to investigate whether a clomiphene citrate (CC) priming protocol could increase ovarian sensitivity in poor ovarian responders. Methods: This single-center retrospective cohort study included 294 patients (374 ovarian stimulation cycles). Of these, 193 cycles were treated by a CC priming antagonist protocol (study group) and 181 by the classical flexible gonadotropin-releasing hormone antagonist protocol (control group). Stimulation data and laboratory and clinical outcomes were compared between the groups. Results: Total gonadotropin dosage and dosage per follicle were considerably lower, the follicle-to-oocyte index was significantly higher, and the gonadotropin duration was shorter in the study group. After adjusting for potential confounders, multivariate regression analysis showed that cumulative ongoing pregnancy remained comparable between the groups (adjusted odds ratio: 0.761, 95% confidence interval: 0.300-1.933, P = 0.566). Age, body mass index, gonadotropin dosage per follicle, and the follicle-to-oocyte index were directly associated with the reproductive outcomes. The result of the sensitivity analysis showed that patients stimulated by the CC priming antagonist protocol were administered less gonadotropin (1,739.09 ± 719.39 vs. 3,114.77 ± 1,171.23, P < 0.001) at a lower gonadotropin dosage per follicle (637.36 ± 373.05 vs. 1286.26 ± 976.66, P < 0.001) and for a shorter duration (6.58 ± 2.23 vs. 9.80 ± 1.90, P < 0.001). Conclusions: The CC priming antagonist protocol offered a convenient and patient-friendly way to increase ovarian sensitivity during ovarian stimulation in poor ovarian responders.

scholarly journals Acupuncture Decreases the Incidence of Post-stroke Dementia: A Taiwan Nationwide Retrospective Cohort Study

2020 ◽  
Author(s):  
Shao-Ang Chu ◽  
Te-Yuan Chen ◽  
Po-Yuan Chen ◽  
Wei-Jie Tzeng ◽  
Cheng-Loong Liang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Acupuncture Treatment ◽  
Lower Probability ◽  
Control Group ◽  
Study Group ◽  
Research Database ◽  
Post Stroke ◽  
Incidence Of Dementia

Abstract BACKGROUND Stroke has been recognized as one of the major causes of adult disability worldwide, and post-stroke dementia may affect up to one-third of stroke survivors. This condition could be prevented if we could recognize and treat it earlier. Acupuncture as a complementary treatment for stroke has been shown to be beneficial for subsequent post-stroke rehabilitation. Our study investigated if acupuncture served additional advantages to decreasing the incidence of post-stroke dementia. METHODS We provide a retrospective cohort study from Taiwan National Health Insurance Research Database. This study compared the incidence of post-stroke dementia between cohorts with and without acupuncture treatment by calculating adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of acupuncture associated with post-stroke dementia using Cox proportional hazard regressions. The study group was composed of 9,547 patients who received first hospitalization for the treatment of stroke between 2002 and 2004; of which, 47,735 comparison patients were defined as the control group. The two groups were followed-up until the diagnosis of dementia presented or until the end of 2007. RESULTS The adjusted HRs of developing dementia among patients with stroke was 4.705 times the average (range, 4.353–5.085), and the incidence of dementia was higher in males. The study group tended to have less incidence of all kinds of dementia after acupuncture treatment, and patients without stroke receiving acupuncture had a lower probability of dementia than those untreated during the follow-up period. CONCLUSIONS This study presents evidence that acupuncture serves as an effective and alternative procedure to lower the risk of post-stroke dementia and the overall incidence of dementia in Taiwanese population.

scholarly journals Prevalence of ovine footrot in Brahmaputra Chars (shoals) in Mymensingh

2016 ◽  
Vol 31 (2) ◽  
pp. 74-83 ◽  
Author(s):  
MM Haq ◽  
MM Rahman ◽  
S Rana ◽  
M Khatun ◽  
K Samaddar
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Management Practices ◽  
Field Survey ◽  
Farm Management ◽  
Housing System ◽  
Study Group ◽  
Housing Environment ◽  
Farm Type

A retrospective cohort study was conducted from July 2012 to August 2013 to determine prevalence of ovine footrot in chars (Shoals) of Mymensingh Sadar Upazila, Bangladesh, centred in Paranganj Union Parishad. A field survey used a prepared questionnaire and investigation of farm management. The prevalence of ovine footrot was 4.2% in the study group of 687 sheep, in 106 farms. The prevalence differed according to farm type and housing system. Prevalence of ovine footrot was higher (9.5%) in farms where sheep and other livestock were housed under the same roof. Prophylactic medication and footbath practice were absent. Common care and management practices were sheep bath, house and floor cleaning, deworming, and therapeutic medication. Highest prevalence (7.0%) was recorded in farms where prophylactic medication and deworming was irregular, and antiseptics were not used in sheep bathing and cleaning of sheep house and floor. The results suggest that improvement of the housing environment and management practices are required to control footrot.Bangl. vet. 2014. Vol. 31, No. 2, 74-83

Tu1788 CLINICAL CHARACTERISTICS AND TREATMENT DIFFERENCES BETWEEN YOUNGER AND OLDER ONSET MICROSCOPIC COLITIS: A MULTICENTER RETROSPECTIVE COHORT STUDY

2020 ◽  
Vol 158 (6) ◽  
pp. S-1161
Author(s):  
Amrit K. Kamboj ◽  
Amandeep Gujral ◽  
Elida Voth ◽  
Daniel Penrice ◽  
Jessica McGoldrick ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Clinical Characteristics ◽  
Microscopic Colitis
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