scholarly journals Tertiary Lymphoid Organs in Rheumatoid Arthritis

2020 ◽  
pp. 119-141 ◽  
Author(s):  
Felice Rivellese ◽  
Elena Pontarini ◽  
Costantino Pitzalis
Keyword(s):  
Rheumatoid Arthritis ◽  
Lymphoid Organs

scholarly journals Tertiary lymphoid organs in systemic autoimmune diseases:  pathogenic or protective?

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 196 ◽  
Author(s):  
William D. Shipman ◽  
Dragos C. Dasoveanu ◽  
Theresa T. Lu
Keyword(s):  
Rheumatoid Arthritis ◽  
Autoimmune Diseases ◽  
Lupus Erythematosus ◽  
Lymphoid Organs ◽  
T And B Cells ◽  
Systemic Lupus ◽  
Disease Pathogenesis ◽  
Systemic Autoimmune Diseases ◽  
Effector Cells ◽  
Secondary Lymphoid Organs

Tertiary lymphoid organs are found at sites of chronic inflammation in autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. These organized accumulations of T and B cells resemble secondary lymphoid organs and generate autoreactive effector cells. However, whether they contribute to disease pathogenesis or have protective functions is unclear. Here, we discuss how tertiary lymphoid organs can generate potentially pathogenic cells but may also limit the extent of the response and damage in autoimmune disease.

Association of vitamin D receptor genotypes with early onset rheumatoid arthritis

2001 ◽  
Vol 28 (1) ◽  
pp. 89-93 ◽  
Author(s):  
J. R. Garcia-Lozano ◽  
M. F. Gonzalez-Escribano ◽  
A. Valenzuela ◽  
A. Garcia ◽  
A. Nunez-Roldan
Keyword(s):  
Rheumatoid Arthritis ◽  
Vitamin D ◽  
Vitamin D Receptor ◽  
Early Onset
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